Iningi Ngokujwayelekile Lisebenzisa Imithi Yokuhlunguphaza Emhlabeni
I-Acetaminophen (igama lomkhiqizo we-Tylenol) yisidakamizwa esetshenziswa kabanzi esithathwa njengokuphephile uma isetshenziswe ngendlela efanele. Kubalulekile ukuba i-acetaminophen isetshenziswe ngendlela eqondisiwe. Ithuba lemiphumela emibi engathandeki kakhulu kakhulu lapho kulandelwa izinkomba. I-Acetaminophen iyatholakala kwimikhiqizo njengeyodwa yithako esebenzayo, nasemikhiqizweni eminingi lapho engeyona eyisithako esisebenzayo kuphela.
Kuyinto edumile yokuphulukisa ubuhlungu futhi eziningi, uma zingenjalo, izindlu zinezikhwama zemithi. Nazi izinto ezingu-10 okufanele wazi futhi uziqonde mayelana ne-acetaminophen.
Ukusetshenziswa
I-Acetaminophen imithi esetshenziselwa ukuphumula ubuhlungu nokunciphisa umkhuhlane.
I-Acetaminophen ihlukaniswa njenge- analgesic ne-antipyretic. Yilapho isetshenziselwa ukuphulukisa ubuhlungu obukhulu kunazo zonke kanye nokunciphisa umkhuhlane emhlabeni. I-Acetaminophen ayinayo izakhiwo eziphikisayo noma kunjalo. I-Acetaminophen isetshenziselwa ukuphatha izinkinga eziningi zezempilo, kuhlanganise nobuhlungu be-arthritis .
Ukutholakala
I-Acetaminophen iqukethe imikhiqizo engaphezu kuka-100 ehlukene nemikhiqizo yenhlanganisela. I-Acetaminophen iqukethe ukubunjwa okungenakubalwa, imikhiqizo ebandayo, amalungiselelo wesono, nokuningi (isib. Sinutab, Midol, Ultracet, Dristan). Ukutholakala okubanzi kwe-acetaminophen, okuthengiswa ngaphezulu kwe-counter kanye nemikhiqizo kadokotela, yenza kube yinye yezidakamizwa ezivame kakhulu ezihlotshaniswa nokubulawa kwesibindi noma ngengozi.
Uma uthatha imikhiqizo eminingi equkethe i-acetaminophen futhi idlulele inani eliphakeme elivunyelwe nsuku zonke, imiphumela emibi kanye nemiphumela engase ibe yingozi kungenzeka.
Ulwazi lwesilinganiso
I-dose yansuku zonke evumelekile ye-acetaminophen ingama 4 amagremu (noma 4000 mg) kubantu abadala kanye ne-90 mg / kg ezinganeni.
I-Acetaminophen iyatholakala njengethebhulethi, ithebhulethi enokwethenjelwa, i-capsule, i-caplet, i-geltab, i-gelcap, ithebhulethi ekhulisiwe okwesikhashana, noma ukumiswa okwesikhashana okumele kuthathwe ngomlomo noma ngaphandle kokudla.
Itholakala futhi njenge-suppository. Amandla njalo iTylenol aqukethe 325 mg we-acetaminophen ngephilisi ngalinye. Amandla engeziwe iTylenol aqukethe 500 mg we-acetaminophen ipilisi ngayinye. Kubantu abadala, amaphilisi ayisishiyagalombili angaphezu kwamandla e-acetaminophen yiwona ophezulu ovunyelwe ngosuku. Uma udlula leyo mali, ubungozi obungozi obukhulu.
Ngo-2011, i-FDA ihlongoze izinguquko ezingeni eliphakeme le-acetaminophen. Ngo-Agasti 30, 2013, uJohnson & Johnson umemezele ukuthi isixwayiso sizovela esikhwameni sezikhumba ze-Extra Strength iTylenol esithengiswa e-US kusukela ngo-Okthoba walolo nyaka nakwamanye amabhodlela eTylenol ezinyangeni ezalandela. Isixwayiso kwakuwukukwazisa umthengi ukuthi izidakamizwa ezingaphezu kwamakhompiyutha aqukethe i-acetaminophen zingabangela ukuhluleka kwesibindi ngokuzumayo uma kuthathwa okuningi.
Umphumela wokubamba
Kumele uqaphele umphumela wokuqoqa lapho uthatha imikhiqizo ehlukahlukene equkethe i-acetaminophen. Njengoba kuchazwe ngaphambilini, imikhiqizo eminingi iqukethe i-acetaminophen. Kungumthwalo wakho ukwengeza inani le-acetaminophen ukuthi uyingenisa nsuku zonke. Ngisho noma uthatha i-acetaminophen kusuka kumkhiqizo ongaphezu kweyodwa, engeza inani eliphelele ukuqinisekisa ukuthi awudluli umthamo ovunyelwe nsuku zonke.
Isibonelo, uma uthatha uNorco 10-325 ngosuku, okulingana no-650 mg acetaminophen kusukela i-Norco eyodwa iqukethe 325 mg i-acetaminophen.
I-Norco iqukethe i- hydrocodone ne-acetaminophen . Uma, ngaphezu kukaNorco ubuhlungu, uthatha imithi ebanda noma ye-sinus equkethe i-acetaminophen, kufanele wengeze inani elifakiwe (ie, engeza i-acetaminophen kokubili eNorco nemithi ebandayo) ukuze uqiniseke ukuthi uhlala ngaphakathi umkhawulo wokuqongelela. Ilebuli ku-Tylenol itusa ukuthi ungathathi umkhiqizo ongaphezu kweyodwa ngesikhathi equkethe i-acetaminophen ukuqinisekisa ukuthi ngeke udlulele amanani angavumelekile.
I-Acetaminophen no-Alcohol
Ukuphuza utshwala ngenkathi uthatha i-acetaminophen akukwaziswa. Uma uphuza utshwala obuthathu noma ngaphezulu nsuku zonke noma ube nesifo sesibindi sesibindi, cela udokotela wakho uma ungathatha i-acetaminophen.
Ukuhlanganiswa kotshwala kanye ne-acetaminophen kungalimaza kakhulu isibindi, kanye nemiphumela engaba yingozi.
Imiphumela Ezingenakwenzeka
I-Acetaminophen imiphumela emibi ingaba yingozi. Yazi uma kufanele ushayele udokotela wakho kunokuba ucabange ukuthi inkinga izophela. Iminye imiphumela emibi ingase ibe izibonakaliso zokuphendula okweqile noma isimo esidinga ukwelashwa ngokushesha, njengokuthi:
- Rash
- I-Hives
- Itching
- Ukuvuvukala
- Ukuthuthumela
- Ukuphefumula okunzima
- Kunzima ukugwinya
Ngo-2013, i-FDA yaxwayisa mayelana nokusabela okungathí sina kwesikhumba okungenzeka nge-acetaminophen. Ngokusho kwe-FDA, " uStevens-Johnson Syndrome kanye ne- necrolysis eyingozi ye-epidermal yizo ezimbili zokwenza isikhumba esibi kakhulu ezihlobene nezimo ezingavamile ku-acetaminophen. Ngokuvamile zidinga ukunakekelwa esibhedlela futhi zingabangela ukufa." Ukusabela okwesithathu kwesikhumba, i-pustulosis ejwayelekile ejwayelekile, ngokuvamile ixazulula ngaphakathi kwamasonto amabili okuyeka imithi. Izixwayiso mayelana nalezi zindlela zesikhumba zenezelwe ekhelini le-acetaminophen. Ngisho noma uthathe i-acetaminophen ngaphandle kwenkinga, ukusabela isikhumba esibi kungenzeka noma kunini.
Yazi Izimpawu Zokuqapha
Izimpawu ezihambisana nokudlula ngokweqile kwe-acetaminophen zingaba sína futhi zidinga ukwelashwa ngokushesha. Izimpawu ezihlobene nokudlula ngokweqile kungenzeka ukuthi kungengozi noma cha futhi kufaka phakathi:
- I-nausea
- Ukuvota
- Ukulahlekelwa kwesifiso
- Ukudideka
- Ukuphunga
- Ukukhathala okukhulu
- Ukusuka okungavamile noma ukulimaza
- Ubuhlungu esiswini (ikakhulukazi ingxenye engakwesokudla)
- Isikhumba noma amehlo aphuzi
- Izimpawu ezifana ne-flu
- Uhudo
- Ukushaya kwenhliziyo okungavamile
Kufanele Uthabathe Kude Nini I-Acetaminophen
Zikhona izincomo kanye nemihlahlandlela yokuthi kufanele uthathe isikhathi eside kangakanani i-acetaminophen uma uziphatha ngokweqile. Izincomo ziphakamisa ukuthi ungathatha i-acetaminophen izinsuku ezingafika ku-3 uma uphatha umkhuhlane, futhi kuze kube yizinsuku ezingu-10 uma uphatha ubuhlungu. Uma izimpawu ziqhubeka ngaphesheya kwaleso sikhathi, xhumana nodokotela ukuze ubone ukuthi kufanele uqhubeke ne-acetaminophen noma ushintshe uhlelo lwakho lwezokwelapha.
Sebenzisa ngesikhathi sokukhulelwa
I-Acetaminophen ihlukaniswa njenge-FDA Isigaba B sokukhulelwa, okungukuthi, akunakwenzeka ukuthi lesi sidakamizwa singalimaza ingane engakazalwa. Uma ukhulelwe, ungathathi i-acetaminophen ngaphandle kokuxoxa nodokotela wakho. I-Acetaminophen idlula ubisi lwebele. Nakuba kubhekwa njengokuphephile ukusebenzisa ngesikhathi sokuncelisa, xoxa nodokotela wakho.
Izwi elivela
Uma kuthathwe ngokusho kwemiyalelo, imiphumela emibi evela ku-acetaminophen ayivamile. Umphumela omubi kunayo yonke ukulimala kwesibindi. I-toxicity yezinso nayo kungenzeka. Umonakalo wokulimala kwesibindi ukwanda nge:
- Amanani amakhulu we-acetaminophen
- Ukusetshenziswa okungapheli kwe-acetaminophen
- Ukusetshenziswa okuhambisanayo kwe-acetaminophen ngotshwala noma ngezinye izidakamizwa okungase kubangele ukulimala kwesibindi
Iqiniso lokuthi i-acetaminophen ithengiswa njenge-over-the pain reliever akusho ukuthi akunemiphumela emibi, kuhlanganise nezinye ezingase zibe nzima kakhulu. Njenganoma yimiphi imithi izinzuzo nezingozi kufanele zilinganiswe. Ngenkathi imithi iphumelela kakhulu njengendlela yokuhlenga ubuhlungu kwabanye abantu, imiphumela yocwaningo eyashicilelwe eLancet (March 2016) iphakamisa ukuthi i-acetaminophen ayinamandla nakakhulu kune-placebo yokwelapha ubuhlungu be-hip noma i-knee kusuka ku-osteoarthritis. Uma uzothatha i-acetaminophen, unake iziqondiso nezixwayiso zokuphepha.
> Imithombo:
> Acetaminophen. Drugs.com. Kushintshiwe ngoMashi 2017.
> Acetaminophen. I-MedlinePlus. Ibuyekezwe ngo-08/15/2014.
> Da Costa et al. Ukuphumelela kwezidakamizwa ezingezona ukuvuvukala ezingelaphekiyo zokwelapha ubuhlungu emadolweni naseqhenqeni i-osteoarthritis: ukuhlaziywa kwe-network meta-analysis. I-Lancet. Ishicilelwe ku-intanethi ngo-03/07/2014.
> I-FDA Ixwayisa nge-Acetaminophen Risk ejwayelekile. I-FDA. 08/01/2013.