Ucwaningo alukhombisi, kodwa isixwayiso se-FDA sibonisa ukuthi kungenzeka ukulahlekelwa umuzwa wokuphunga lapho usebenzisa imikhiqizo ethile yeZicam.
Isixwayiso, esakhishwe ngoJuni 16, 2009, sithi bonke abathengi kufanele bayeke ukusebenzisa yonke imikhiqizo engaphakathi kwe-Zicam efaka i-zinc. Ngesikhathi sokuxwayiswa okukhishwe, i-FDA yayithole izikhalazo ezingaphezu kuka-130 ukuthi imikhiqizo elandelayo ye-Zicam yabangela ukulahlekelwa umuzwa wokuhogela:
- I-Zicam Cold Remedy Nasal Gel (15ml)
- I-Zicam Cold Remedy Swabs (ukubala okungu-20)
- I-Zicam Cold Remedy Swabs, Usayizi Wezingane (20 ukubalwa)
Ngesikhathi esifanayo, i-FDA ithumele incwadi kumkhiqizi wemikhiqizo, i-Matrixx Initiatives, Inc., ekwazisa ukuthi le mikhiqizo ayikwazi ukudayiswa ngaphandle kwemvume ye-FDA, engenayo (imikhiqizo okwamanje ithengiswa ngemithi yokwelapha ekhaya ). Ngaphezu kwalokho, imikhiqizo ayizange ibe nezixwayiso ezifanele mayelana nobungozi bokulahlekelwa umuzwa wokuphunga emaphaketheni abo kanye namalebula.
Lesi sixwayiso sisekelwe kumbiko wabathengi kuphela. Labo abakholelwa ukuthi baphelelwa umuzwa emva kokusebenzisa le mikhiqizo kumele baqale babone umsebenzi wabo wezempilo bese bexhumana ne-FDA.
Ukuphepha
Kuye kwaqhutshwa izifundo ezimbili eziphawulekayo futhi zanyatheliswa eziphathelene nokukhishwa kwe-anosmia (ukulahlekelwa umuzwa wokuhogela). Owokuqala wenziwa nguDkt. Burton Slotnick futhi wahlola umphumela we-zinc sulfate, ohluke kwi-ginccon zinc eZicam, esikhungweni sephunga emantwini.
Lelo cwaningo lathola ukuthi ukulahlekelwa okwesikhashana kunomqondo wokuhogela lapho amagundane anikezwa ukuphakama okukhulu kwe-zinc sulfate.
Ucwaningo lwesibili lwalwenziwa noDkt. Slotnick kanye neqembu labacwaningi kodwa lisekelwe ngokuyingxenye yi-grant evela kuMatrixx. Lolu cwaningo lwamuva luvivinye umphumela we-zinc gluconate, isithako esisebenzayo kuZicam, kumagundane.
Imiphumela yalolu cwaningo ibonise ukuthi ukulahlekelwa okuyingxenye kanye nesikhashana nje kunomqondo wokuhogela kwamagundane lapho kunikelwa amanani amaningi kakhulu (okuphakeme kakhulu kunomthamo ojwayelekile kubantu). Kodwa-ke, umonakalo wabuyiselwa phakathi kwamasonto ambalwa.
Kubalulekile ukukhomba ukuthi zombili lezi zifundo zenziwa ngamagundane; Kumele siqaphe lapho sisebenzisa imiphumela yokuhlolwa ezilwaneni kubantu. Ngenxa yokuthi akubanga nezezifundo ezinkulu ezihlolisisa le ndaba eyenziwa kubantu, asikwazi ukusho ngokucacile ukuthi umkhiqizo ubangele noma awubangeli i-anosmia kubantu.
Ukusebenza
Ayikho i-Zicam noma i-Cold-Eeze elawulwa yi-FDA, kodwa bobabili bathi banciphisa ubude bomkhuhlane. Umkhiqizi uthi lokhu kuqinisekiswe ekucwaningweni yi-Cleveland Clinic, indawo yokucwaninga. Kodwa-ke, ngokusho kocwaningo, imiphumela ye-zinc esiswini yokufiphaza emakhazeni avamile ayisaqondakali.
Izinhloko ezidlule
Amakhulu abantu ahileleke enkantolo ngokumelene nabakhiqizi bama-gels aseZicam namaCold-Eeze, bathi balahlekelwa umuzwa emva kokusebenzisa umkhiqizo, oye waxazululwa ngoJanuwari 2006. Kukhokhwa kwezigidi ezingu-12 zamaRandi, le nkampani ayivumeli ukungalungi noma ukungena ukuthi imikhiqizo yabo ibangele ukulahlekelwa umuzwa wokuhogela.
> Imithombo:
> McBride K, uSlotnick B, uMargolis FL. Ingabe ukusetshenziswa kwe-Intranasal ye-Zinc Sulfate Kukhiqiza i-Anosmia ku-Mouse? Isifundo se-Olfactometric ne-Anatomical. Chem Senses. 2003 Oct; 28 (8): 659-70.
> Mossad, Sherif B. "Izifo Eziphefumulayo Eziphezulu Zokuphefumula." Umkhankaso wokuLawula izifo zeCleveland Clinic 29 Julayi 2005. 03 Nov 2006.
> Slotnick B, Sanguino A, Umyeni S, uMarquino G, uSilberberg A. Ukunyuka kanye ne-Epithelium e-Olfactory ku-Amagundane athathwa nge-Zinc Gluconate. I-Laryngoscope. 2007, 117 (4): 743-9.
> "Ukuxwayiswa kwiZicam Intranasal Zinc Products ezintathu." I-FDA Updates Updates 16 Juni 09. Ukuphathwa kwe-US nokuDrug. 16 Juni 9.