Kungenzeka ukuthi ube nezinga "elivamile" le-TSH futhi usazizwa ungavuli
Uma ususelwa esikhundleni se-hormone ye-thyroid futhi unesimo se-hormone se-thyroid eshukumisayo (TSH) esisezingeni elijwayelekile-okwamanje usenayo ibanga lezimpawu ezihlobene ne -roid-ungase ube esinye seziguli ze-thyroid ezihlushwa i- hypothyroidism engaphansi .
Abantu abangamaphesenti angama-15 ase-US abane-hypothyroidism, noma i-thyroid engasebenzi, bayazizwa bengaphili kahle naphezu kokuba baphathwe lesi sifo, ngokusho kocwaningo luka-2016 olwanyatheliswa kuyi- Journal of Clinical Endocrinology ne-Metabolism .
Lokhu kusho ukuthi abantu abayizigidi eziyi-1.5 kuya kwezi-1.8 baseMelika njengamanje bathatha ukwelashwa kwe-hormone ye-thyroid banezimpawu eziqhubekayo ze-thyroid engasebenzi. Uma ucabanga ukuthi ulungele le ncazelo, kubalulekile ukuba nengxoxo nodokotela wakho mayelana namazinga aphezulu we-TSH kanye nokukhethwa kwezidakamizwa ze-thyroid.
Yini Echotshozwa Hypothyroidism?
Leli gama libhekisela ku-hypothyroidism ezingeni lamaselula okusho ukuthi usenayo izimpawu ze-hypothyroidism ezifana nokukhathala, ukunyuka kwesisindo , ukucindezeleka, i-fibromyalgia / imisipha kanye namazinyo ohlangene nezinhlungu, ukulahlekelwa izinwele noma izinwele ezinomile / ezomile , ukungaboni kahle , ukuqothuka, ubuchopho obuchopho ngaphezulu-naphezu kokuthatha inani eliphakanyisiwe lokushintshwa kwegciwane futhi ube nezinga "lejwayelekile" legazi le-TSH. Ngeshwa, amazinga ajwayelekile e-TSH egazi alayishwa kakhulu odokotela abaningi kunamaguli wesiguli lapho behlulela ngokwanele ukwelashwa.
Kunezizathu ezimbili lokhu okungenzeka. Okokuqala, odokotela abathile bakholelwa ukuthi ukuhlinzeka ngehomoni ye-thyroid ngokwanele ukuze uthole isiguli phakathi kwamanqanaba ajwayelekile ajwayelekile e-TSH anele.
Esesibili, ngokusobala isizathu esivame kakhulu ukuthi ukwelashwa okujwayelekile kwe-Synthroid, Levoxyl, Levothyroid, Eltroxin, noma i-Euthyrox (i-levothyroxine ejwayelekile) kungenzeka ukuthi akwanele ukuba abanye abantu bazizwe kahle. I-Levothyroxine ibanga lezokwelapha imithi ye-T4, lapho umzimba kufanele uguquke ube yi-T3, i-hormone esebenzayo.
I-T4 ayisebenzi. Kodwa-ke, abanye abantu bangase balwe nobunzima bokuguqula i-T4 ibe ngamanani alinganayo we-T3, beshiya ngezimpawu eziqhubekayo ze-hypothyroid.
Uma ungazizwa kahle nge-levothyroxine monotherapy, ungase ufune ukuzama "ukwelapha okuhlanganisayo" okuyimithi equkethe kokubili T3 no-T4. Ngisho noma lokhu kusekelwa yi-American Thyroid Association, odokotela abaningi abanalo ulwazi abalutholayo.
Izinga le-TSH
Abanye be-endocrinologists bakholelwa ukuthi i-TSH engaphansi kwe-2 ilungile kakhulu kubantu abaningi ukuba bazizwe kahle futhi bagweme ukuba nezimpawu ze-hypothyroid noma ze-hyperthyroid. Kukhona futhi ucwaningo olubonisa ukuthi amanani ngaphezu kwe-TSH ye-2 angase abuye amele amazinga angavamile .
(QAPHELA: Amazinga e-TSH avame ukugcinwa aphansi kunamaphesenti angu-1 kwalabo abasinda emdlavuza we-theroid-inqubo ibizwa ngokuthi ukucindezelwa kwegciwane-ukusiza ukuvimbela umdlavuza ukuphindaphinda.)
- I-TSH Ngaphansi kuka .3 - Lokhu kubhekwa ukuthi kungenzeka i-hyperthyroid (i-hormone ekhulu kakhulu ye-thyroid) kuma-labs amaningi e-US Ungase ube nokukhathazeka, ukuthola kunzima ukulala, izinwele eziphuma ngaphandle, isifo sohudo, nezinye izimpawu.
- I-TSH 1 kuya ku-2 -Izinga eliphezulu elivamile labantu abaningi. Lona ububanzi be-TSH lapho iningi labantu lizizwa lihle kakhulu. Ngezinye izikhathi kubhekwa "phansi kakhulu" odokotela abangenalwazi.
- TSH .3 kuya ku-4.5 - "Ibanga lokubhekisela" ngokusho kwamanye amazinga ebhodi. Abanye abantu bazizwa kahle kulolu hlu, kepha abaningi bahlushwa izimpawu ze-hypothyroidism ezingeni eliphansi lapho i-TSH ingaphezulu kwe-2.0. A
- TSH 4.5 kuya ku-10 - Kucatshangwa "ama-subclinical hypothyroidism" amazinga, kodwa ngokumangalisayo, odokotela abathile ngeke baphathe ngisho nalawa mazinga futhi bangabonakali izimpawu ze-hypothyroidism ezizwa iziguli kuleli zinga kuze kube yi-hypothyroidism ngokwayo. Abantu abaningi banezibonakaliso kula mazinga.
- TSH Ngaphezulu kuka-10 - Kucatshangwa ukuthi i-hypothyroid efanelwe ukwelashwa odokotela abaningi.
Ungase Udinge i-T3 ukuze uzizwe kahle
Abanye abantu abazizwa kahle nge-levothyroxine / T4 kuphela izidakamizwa (njenge-Synthroid) futhi bazizwa bebheke kakhulu-bathatha i-T3.
Abanye baye baphumelela ukwengeza i-T3, njenge-Cytomel noma nge-compounded, i-T3 ekhishwe isikhathi, ku-levothyroxine yabo. Ekugcineni, abanye baye baphumelela ngezikhali , ukukhishwa kwe-hormone yemvelo yemvelo . Kunezinketho eziningi ze-hormone yokushintsha esikhundleni se-thyroid .
Kuyathakazelisa ukuthi Kusabhekwa njengengxabano yokusebenzisa i-T3 kubantu abane-hypothyroidism nge-innovative encane noma engamalungu omhlaba wezokwelapha, naphezu kocwaningo olubonisa ngokucacile isidingo se-T3 kwiziguli eziningi zegciwane. Abantu abaningi banezinga elijwayelekile noma elincane eliphansi le-TSH, nokho namanje, bahlupheka beqhubeka nezimpawu ze- hypothyroidism . Kulezi zimo, ukungezwa kwe-T3 kusize ukukhulula ukucindezeleka, ubuchopho obuchopho , ukukhathala nezinye izimpawu. Lolu lwazi mayelana ne-T3 luyinto eguquguqukayo futhi lunomthelela omkhulu kubantu abangazizwa kahle ezindlini zabo zokwelashwa zamanje! Ukuze uthole olunye ulwazi, bheka umbiko wami ogcwele kulolu cwaningo.
Indlela Yokuguqula Ingxoxo Ngodokotela Wakho
Uma usuhlushwa izimpawu ze-hypothyroidism naphezu kokwelapha, isinyathelo sakho sokuqala ukuyiloba lokhu ngendlela ongabuyekeza ngayo kalula nodokotela wakho. Ithuluzi elihle lokusiza yi- hypothyroidism yokuhlola izibonakaliso , okunikeza uhlu lwezinto eziyingozi kanye nezimpawu ongazithatha kudokotela wakho ukuze usize uthole ukuxilongwa, noma wenze ingxabano ukuthi izimpawu zakho ze-hypothyroid azixazululwa ukwelashwa kwakho kwamanje.
Ngaphambi kokuba uxoxe nodokotela, ngiphinde ngikusize ukuthi ufunde imibuzo eyisithupha ebaluleke ngempela okufanele ubuze udokotela wakho mayelana ne-hypothyroidism yakho, kanye nemibandela esemqoka umuntu osanda kuthola ukuthi une- hypothyroidism evame ukubuza-njengokuthi kungakanani kuthatha ukuzizwa ungcono ngemuva kokuqala ukwelashwa, izingozi zempilo yesikhathi eside, kungakhathaliseki ukuthi uzothola i-goiter, ukukhathala nokuzuza kwesisindo nendlela yokulwa nabo, nokuningi.
Uhlomile ngolwazi kanye nohlu lwakho lokuhlola, kufanele uhlale phansi futhi uxoxe nodokotela wakho ngezinga lakho elihle le-TSH , nokuthi ngabe kufanele yini ucabangele ukungezwa kwe-T3 ekwelashweni kwakho kwe-hormone esikhundleni sakho.
Ungase futhi udinga izinhlamvu ezithile ukuze udokotela wakho alalele futhi aqonde. Ukusiza, kunezincwadi ezehlukene engiziphakamisela kuzo zonke iziguli ze -roid. Bheka I-Bookstore ye- Thyroid ngemibono.
Uma udokotela wakho engeke akhulume izinketho noma wenqaba ukucubungula ukwelashwa kwe-T3, khona-ke uzodinga ukuthola udokotela ofuna ukuba ngumlingani wakho ebuhleni.
> Umthombo
> USarah Peterson, u-Elizabeth A. McAninch, u-Antonio C. Bianco. Ingabe i-TSH evamile efana ne-"Euthyroidism" ku-Levothyroxine Monotherapy? I Journal of Clinical Endocrinology & Metabolism , 2016; jc.2016-2660 DOI: 10.1210 / jc.2016-2660