Ukwelashwa Kwe-Asthma Nge-Inhlanganisela I-Steroids Plus I-LABA Engayifakiwe
Yiziphi Imikhiqizo Yokuhlanganiswa Njengo-Advair, i-Symbicort, i-Dulera ne-Breo?
I-Advair, i-Symbicort, i-Dulera, ne-Breo yimithi yokulawula ehlanganisa izidakamizwa ezimbili zibe yinye inhaler (ngokwemithi yezokwelapha: i-steroids engabhalisiwe ne-agonist esebenza isikhathi eside). Ucwaningo oluthile lubonisa izinzuzo ezingenzeka zokuhlanganisa le mithi ibe yi-inhaler eyodwa ngokuphambene nokuyibeka ngokwahlukana.
Ukwengeza, izifundo ezimbalwa ziphakamisa ukuthi kungenzeka ukusebenzisa umkhiqizo ohlangene njenge-inhaler yakho kuphela kokubili kokulawula kanye nezimpawu eziyingozi, kodwa kufanele uxoxe ngalokhu nodokotela wakho we-asthma ngaphambi kokuzama lokhu.
Izinzuzo ze-Advair, i-Symbicort, i-Dulera, ne-Breo
- Kungcono kakhulu
- Ukwandisa ukuhambisana nezidakamizwa
- Okubizayo kancane
- Amanani amancane we-steroid engatholakali enganciphisa imiphumela emibi
Izinkinga ze-Advair, i-Symbicort, i-Dulera, ne-Breo
- Ukuzivumelanisa nezimo ezincane ekulandiseni
- Uma usebenzisa imithi ukuze unciphise izimpawu ezinzima, ungathola umthamo ophezulu kakhulu we-steroid kunalokho okwenziwe njengamanje.
Imikhiqizo Yobumbano Ifana ne-Advair, i-Symbicort, i-Dulera, ne-Breo Work?
Imikhiqizo yokuhlanganiswa efana ne-Advair ne-Symbicort iqukethe imithi emibili esebenzayo eyenza ukuphatha i-asthma yakho ngokuhlukile:
- I-steroid engenalutho: Izenzo emoyeni wamaphaphu ukuncipha ukuvuvukala.
- I-LABA : Inikeza ukuhlukunyezwa kwegazi ngokuziphumuza imisipha ebushelelekile emaphashini nokwenza ukuhamba kwemimoya ibe nzima, ngaleyo ndlela kunciphise izimpawu.
Izibonelo
- I-Advair : Iqukethe i-steroid Fluticasone (i-Flovent) ne-LABA Salmeterol (i-Serevent)
- I-Symbicort : Iqukethe i-steroid, i- Budesonide (i-Pulmicort) ne-LABA Formoterol (Foradil)
- I-Dulera: Iqukethe i-Mometasone ye-steroid ne-LABA Formoterol
- I-Breo: Iqukethe i-steroid Fluticasone futhi i-LABA Vilanterol
Imiphumela emibi yemikhiqizo efana ne-Advair, i-Symbicort, i-Dulera, ne-Breo
Njengezinye izidakamizwa eziningi, amaphesenti amancane kuphela weziguli azithola imiphumela emibi. Imithelela engaba khona ngokuvamile ifana nalezo zombili i-steroid ephazamisekile ne-LABAs. Yonke inhlanganisela ye-steroid kanye ne-LABA ithwala isixwayiso se-"Black Box" kwamanye ama-LABA kanye nemiphumela emibi engaba khona ye-steroid engasebenzi.
Lesi sixwayiso sisekelwe emininingwaneni evela kwesinye sezifundo zakuqala ezihlola ama-LABA azwakala ukufa kwabantu abangu-13 kwabangu-13,176 abagulayo baphathwa nge-LABA kwamasonto angu-28 ngokubhekene nokufa kweziguli ezithola indawo yokuhlala (azitholanga i-LABA) 3 ku-13 179. Ngenkathi le nombolo incane kakhulu futhi kunezinkinga eziningana nezifundo eziholela esixwayisweni, i-FDA yabona ukuthi ihlakaniphile iziguli ezizokwaziswa.
Ngokwesimo esiyingqayizivele ukuya kwesifo se-asthma esinamandla esinezela i-LABA kubonakala sengathi iphumelela kakhulu kunokuphindaphindiwe umthamo we-steroid engatholakali futhi yindlela yokwelashwa ekhethiwe yalesi sizathu. Njengoba kukhonjisiwe ngaphambili, inhlanganisela iye yavumela ezinye iziguli ukuba zifinyelele ukulawulwa ngamazinga aphansi futhi zinciphise ingozi yemiphumela emibi ngenxa yesilinganiso esincane. Izincomo zamanje lapho kuqaliswa ukwelashwa kuvumela i-steroid engenayo isilinganiso esiphakathi noma isitifiketi esincane se-dose kanye ne-LABA.
Ingabe Ingxube Ye-Asthma Inhalers Ingasetshenziswa Njenge-Asthmatics Inhaler Yodwa?
Noma kunini lapho udinga imithi eyodwa kuphela, mhlawumbe ithuba elingcono lokuthatha imithi ngendlela efanele. Kodwa-ke, kunezizathu eziningi zokuthi kungani i-asthmatics isebenzisa okungaphezulu kweyodwa inhaler.
Kodwa-ke, isifundo eshicilelwe eLancet sibonisa ukuthi iziguli ezinomqondo ohambelana nesifo sofuba esibi kakhulu zingenza kangcono nge-inhaler eyodwa uma kuqhathaniswa ne-inhalers ehlukene yokondliwa nokuhlengwa. Amamethrikhi amaningana abalulekile athuthukiswe kuleli qembu njengengozi yokuhlaselwa kwesifo se-asthma, ukunakekelwa esibhedlela, noma isidingo sokunakekelwa okuphuthumayo. Ucwaningo lwesibili lubonakala lusekela le nqubo.
Njengoba kunikezwe ukuthi amaphesenti amakhulu eziguli ze-asthma awasebenzisi njalo imithi yabo yokulawula i-asthma ngokunembile, lokhu kungase kube inketho esikhathini esizayo. Kodwa-ke, le nqubo okwamanje ayisekelwe yi-US Asthma Guidelines ngakho kudingeka uqiniseke ukuthi uxoxisana nomhlinzeki wakho we-asthma ngaphambi
Isifingqo
Imikhiqizo yokuhlanganiswa ingaba ithuluzi eliwusizo lweziguli ezingakwazi ukuphumelela ukulawula i-asthma yazo kwi-steroid engatholakali yedwa. Wena nodokotela wakho kudingeka nikhulume ngezingozi kanye nezinzuzo ze-combination combination futhi qinisekisa ukuthi wazisa udokotela wakho nganoma yisiphi isifo se-asthma yakho.
> Imithombo:
Nelson HS. Ukwelashwa Kokuhlanganiswa Kwama-agonists A-Long acting Agents kanye ne-Corticosteroids Engenayo I-Management of Chronic Chronic Asthma. Imibiko Yezifo Zezifo Eziphuthumayo Nama-Asthma 2005, 5: 123-129.
I-National Heart, Lung, ne-Blood Institute. Kufinyelelwe: Mashi 4, 2016. Umbiko wePhaneli Yabahloli 3 (EPR3): Izinkombandlela Zokuthola Ukuhlolwa Nokuphathwa Kwe-Asthma