Okudingeka Ukwazi Ngale Mithi Ye-Interferon
I-Rebif (i-interferon beta 1-a) ingenye yezinhlobo eziningi zokwelashwa eziguqulwa yisifo ekuphatheni i-MS yokubuyisela kabusha (RRMS). Njengamanye ama-interferon therapies, i-Rebif inganciphisa inani lokubuyiselwa kabusha komuntu onama-RRMS anesilinganiso sesithathu. Lokhu kuhle, kodwa kukhona izinto ezibalulekile zokwazi mayelana neRebif, kufaka phakathi izinzuzo zayo ngaphezu kweminye imithi kanye nokungahleleki nemiphumela emibi engase ibe khona.
Izinzuzo kanye Nokwamukela Ukuthatha Rebif
Izinaliti zeRebif zincane kakhulu futhi zijova zingaphansi kwamagama-ngamanye amazwi, inaliti kufanele ingene ngaphansi kwesikhumba, okungaba buhlungu kakhulu kunezijova ezijulile. Ngakolunye uhlangothi, u-Rebif une-pH ephansi, ngakho-ke yinto enamandla futhi engenza kube buhlungu kancane uma ifakwe. Futhi, i-Rebif idinga ukuthathwa kathathu ngesonto, kanti amanye ama-interferon adinga ukujova kanye kanye ngesonto.
Uma u-Rebif, kuzodingeka ube nomsebenzi wegazi njalo ukuze uhlole izibalo ezingaphansi kwegazi kanye nezinkinga zesibindi futhi kuzodingeka uqashwe ngokucophelela ngokucindezeleka. Kuhle ukuphawula ukuthi ukucwaninga ukuphakamisa ukucindezeleka kuyingozi kakhulu ngeRebif kunemithi efanayo.
Ukwengeza, i-Rebif ilula ukuhamba nayo: Iza kuma-syringes asetshenzisiwe (ayikho ukuxuba) futhi ayigcinwa ebanda efrijini.
Imiphumela emibi engenzeka
Imiphumela emibi yeRebif ifana neyenye imithi yokwelashwa e-interferon.
- Izimpawu Ezifana Nezikhuhlane. Lokhu kufaka phakathi umkhuhlane, izikhukhula, ukujuluka, ama-muscle aches, nokukhathala okuhlala amahora angu-8 noma ngaphezulu. Lezi zimpawu ngokuvamile zimbi nakakhulu ngemva kokujola kokuqala futhi ziyancipha kancane kancane ngomjovo ngamunye. Enye indlela ongase ukwazi ukugwema ukubhekana ngayo nezimpawu ezifana ne-Rebif ezinjenge-friwu ukuqala ngomthamo ophansi futhi ukwandise umthamo ogcwele kancane kancane emavikini ambalwa. Ukuthatha ibuprofen noma i-acetaminophen amahora ambalwa ngaphambi nangemva kokuthi ujobe i-Rebif nakho kungasiza ekunciphiseni izimpawu.
- Amabala Abomvu. Ungase ubone lezi zivalo esikhumbeni sakho lapho ufaka khona inaliti. Amachashazi angahlala amasonto amaningana futhi ezimweni ezingavamile ahlahlele zibe izilonda, okuthiwa i-injection-site necrosis. Ukushintshanisa izindawo lapho uzibeka khona izibhamu kungasiza ekunciphiseni ingozi yokwenza isikhumba.
- Ukulimala kwesibindi. Abanye abantu abathatha iRebif baye babhekana nezinga eliphezulu le-enzyme yebindi yegazi nesibindi sokuvuvukala kwesibindi. Udokotela wakho uzoqapha impilo yesibindi sakho njalo ngesikhathi uRebif kodwa futhi kufanele ubheke izibonakaliso zenkinga ekhona. Uma uqaphela ukuthi uqala ukulimaza kalula noma ukuthi isikhumba sakho noma abamhlophe bamehlo akho baqala ukubheka yellow, bheka udokotela wakho ngokushesha.
- Izinguquko egazini. I-Rebif inganciphisa inani lamaseli abomvu namhlophe egazini lakho, futhi kubangele ukunciphisa inani lamaplatelets, okusiza iwashi legazi).
- Ukuphendukela kwe-allergenic: Nakuba kungavamile, abanye abantu baye babhekana ne-Rebif ngemuva kwesilinganiso sokuqala noma ngisho nangemva kokulinganisa okuncane.
Kungase kungabi ephephile kumuntu onenkinga yokuthumba ukuthatha uRebf, futhi abesifazane abakhulelwe kufanele bangasebenzisi lesi sidakamizwa: Izifundo zezilwane ziye zathola ukuthi zingalimaza izingane. Uma usuRebif futhi ufuna ukukhulelwa, udokotela wakho angase ayeke ukuthatha Rebif izinyanga ezintathu kuya kwezinyanga ngaphambi kokuba uqale ukuzama ukukhulelwa.
Imithombo:
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I-National MS Society. " Izifo-Ukuguqula Imithi Ye-MS ." 2016.
Iqembu le-PRISMS Yokufunda. "I-PRISMS-4: Ukusebenza Kwesikhathi Eside E-Interferon-Beta-1a ekubuyiseleni i-MS." I-Neurology 2001; 56: 1628-1636.
I-Panitch H, i-Goodin DS, uFrancis G, et al. "Okungahleliwe, Ucwaningo Lokuqhathaniswa Kwe-Interferon Beta-1a Imigomo Yokwelapha ku-MS: I-EVIDENCE Trial." I-Neurology 2002; 59: 1496-1506.
Smith B et al. Ukubuyekezwa kwezidakamizwa: Izifo-Ukuguqula izidakamizwa ze-Multiple Sclerosis: Ukubuyekeza kokugcina 1 Umbiko. "Portland (OR): University of Oregon Health and Science; 2010 Aug.