I-IBD ingathinta amadoda nabesifazane ngokuhlukile
Ngokuvamile, abesifazane bahlakulela izimo ezithintekayo ezizimele noma izivikeli zamasosha omzimba kunamadoda. Ngenkathi isifo sofuba esivuvukalayo (IBD) , esibhekwa njengesimo somzimba sokuzivikela, sibonakala sithinta izinombolo ezilinganayo zamadoda nabesifazane , izifundo ezithile zibonise ukuthi i-IBD ingathinta amadoda nabesifazane ngokuhlukile. Ikakhulukazi, isifo sikaCrohn esikude kakhulu-siboniswa ukuthi sinezinto ezihlukahlukene kakhulu ngokuthinta kanjani amadoda nabesifazane ngezindlela ezahlukene.
Kodwa-ke, kukhona ucwaningo oluthile olubandakanya ukuthi isifo sofuba esiswini sithinta kanjani ubulili. Kungenzeka ukuthi ama-hormone nezinye izici ezithile zobulili zibamba iqhaza endleleni ezinye izifo, njenge-IBD, ezithinta ngayo amadoda nabesifazane ngokuhlukile, kodwa kwezinye izimo zingase zihlobene nokuthi amadoda nabesifazane (nabafana namantombazane) bathola kanjani ukwelashwa izifo.
Esinye sezizathu zokuthi i-IBD ingase ihluke kanjani emadodeni nakwabesifazane kungenxa yokuchazwa kwezici ezingase zibe yingozi. Abacwaningi abasasazi ukuthi yini ebangela imbangela ye-IBD , kodwa kunezinye imibono mayelana nokuthi yini engabangela lesi sifo kwabanye abantu. Izibalo ezihlobene ne-IBD ziye zaqanjwa, kodwa akuwona wonke umuntu onalezi zakhi zofuzo eziqala i-IBD, okusho ukuthi kukhona okuthize (noma ukulingana okuningana) okwenza ukuba kuthuthukiswe. Lezi zimbangela zingase zibe yendalo, njengento ethile abantu abaye bayibonakala ngayo ngesikhathi sokuphila kwabo, noma kungaba okuthile emzimbeni, njengama-hormone.
Kungenzeka ukuthi kukhona izinto ezinjalo esebenza ndawonye eziholela ekuthuthukiseni kwe-IBD kwabanye abantu.
Ama-antibiotics kanye neengozi ye-IBD kubafana nabesilisa
Enye yalezi zinto ezingabangela i-IBD ihlanganisa nokusetshenziswa okuphindaphindiwe kwama-antibiotic. Ucwaningo olulodwa lwathola ukuthi abafana bangase bahlakulele i-IBD kaningi ngemuva kokuthola ama-antibiotic njengengane kodwa enye isifundo sathola ukuthi abafana banqunywe ama-antibiotic ngaphezu kwamantombazane.
Lokhu kusho ukuthi akusaziwa ngokuqinisekile uma abafana bengaba namathuba amaningi kunamantombazane ukuthuthukisa i-IBD ngemuva kokusetshenziswa kwamagciwane ngonyaka wokuqala wokuphila. Ucwaningo lubuye lubonise ukuthi isifo sikaCrohn sitholwa kaningi, ngamaphesenti angu-75 amacala, ngemva kokuthola izingane noma izingane eziningi izifundo zokulwa namagciwane ngesikhathi beyingane.
Ngokuvamile, amadoda angase ahlakulele ukutheleleka ngama-parasites, isikhunta, amabhaktheriya, namagciwane kunabesifazane. Kucatshangwa ukuthi amadoda anenkinga eningi ngokuthola izifo ezithathelwanayo kunabesifazane ngenxa yokuphendula kwe-immune ephansi. Isivikelo somzimba sokuzivikela komzimba sibonakala sisabela ngendlela ehlukile emadodeni kunokuba senzeke kwabesifazane ngenxa yokuhlukahluka kwamahomoni wesilisa nowesifazane. Amahomoni angamadoda angabangela ukuthi amasosha omzimba asebenze kangcono ukulwa nokutheleleka. Ngaphezu kwalokho, kungase kube nesici sesibili emsebenzini, lapho ama-hormone wesilisa nawo anethonya kumagciwane afanele ukulwa nezifo. Kungenxa yalezi zizathu ukuthi amadoda nabafana bangagula ngezifo kaningi futhi lokhu kungabangela isidingo sokwelashwa ngama-antibiotics.
Isithasiselo nengozi ye-IBD kwabesifazane nabesifazane
Njengoba isithasiselo sisusiwe , ngokusebenzisa ukubizwa okuthiwa i-appendectomy, kungenye into engaba khona enobungane obunzima ne-IBD.
Ngemuva kokuthi isithasiselo sisusiwe, ucwaningo luye lwabonisa ukuthi kukhona umkhuba ongena engozini yokwanda kwesifo sikaCrohn kodwa kunciphisa ingozi yokulonda i-ulcerative colitis. Ingozi eyanda kakhulu yesifo sikaCrohn yayiphakeme ngisho nakakhulu kwabesifazane kunabesilisa, futhi yahlala ngaleyo ndlela iminyaka engama-20 u-appendectomy.
Abesifazane Nengozi Yezikhumba
Uhlobo olulodwa lwesibonakaliso esingeziwe emathunjini esithinta inani elikhulu labantu abane-IBD yizinkinga zesikhumba. Ngokuyinhloko, kunezimo ezimbili zesikhumba ezihlobene eduze ne-IBD, i- erythema nodosum ne- pyoderma gangrenosum . Ucwaningo olulodwa lubonise ukuthi kunezici eziningana ezabonakala zihambisana nezindlela zokuthuthukisa esinye sezimo zesikhumba.
Ngaphandle kokuthola ukuthi une-IBD esemncane, futhi enesifo sikaCrohn, esinye isilungiso esandisa ukwanda kwalezi zimo zesikhumba kwaba ubulili. Abesifazane babe nethuba lokuthuthukisa i-erythema nodosum ne-pyoderma gangrenosum kunamadoda ane-IBD. Ukwelashwa kwangaphambilini ngemithi ye- biologic kubonise ingozi ephansi yalezi zimo zesikhumba kulolu cwaningo.
Amadoda Ane-IBD kanye Nengozi Yokugula Kwesibindi
Uhlobo lwesifo sesibindi esivame kakhulu emadodeni kunabesifazane yi- primary sclerosing cholangitis (PSC). I-PSC ivame kakhulu kubantu abane-ulcerative colitis kunabantu abanesifo sikaCrohn. Umuntu ojwayelekile ne-PSC uyindoda eneminyaka ephakathi ubudala futhi ene-ulcerative colitis, nakuba i-colitis ngezinye izikhathi ingatholakali ngaphambi kokuba i-PSC itholakale. Abesifazane abanama-PSC ngokuvamile abanayo i-IBD. I-PSC yisimo esingavamile, kanti ngenkathi sinzima futhi singadinga ukufakelwa kwesibindi, iziguli eziningi zihamba kahle ngemva kokwelashwa.
Umehluko Ngemva Kokuhlinzwa Kwabesilisa Nabafazi
Ngezici eziningi ze-IBD, amadoda nabesifazane babonakala befana ngokufanayo: iminyaka yokuxilongwa kanye nesikhathi sokuhlinzwa kokuqala esimweni se-Crohn's disease, isibonelo. Kodwa-ke, emva kokuhlinzwa komthengisi, isifundo esisodwa sathola ukuthi abesifazane banesikhathi esifushane (iminyaka engu-4.8) kunamadoda (iminyaka engu-6.5) ngaphambi kokuba isifo sikaCrohn siphinde siphume. Abesifazane nabo baboniswa amathuba amaningi okudinga imikhakha ye-ileocecal (okuyinto ukususwa kwengxenye yokugcina yamathumbu amancane ) ukuphatha isifo sabo se-Crohn kunamadoda.
Izifo zePeriyard In Men and Women
Indawo ye- perianal ingxenye yecala elingemuva elizungeza i- anus . Isifo sikaCrohn ikakhulukazi singathinta le ndawo yomzimba futhi kubangele izinkinga ezifana ne- fistula (okuyinto umhubhe ongajwayelekile phakathi kwemigodi emibili yomzimba) nezilonda. I-fistula ithinta amadoda nabesifazane nge-IBD ngokulinganayo kodwa isifundo esisodwa sibonise ukuthi ezinye izimo ze-perianal (njengezilonda) zivame kakhulu kubantu besifazane abanesifo sikaCrohn kunabesilisa.
Ingabe Kunesimo Sezinsizakalo zobulili Ezifundweni?
Kunezinto ezimbalwa ezingase zenzeke ezingase zilandele ezinye umehluko ucwaningo lubonisa ukuthi i-IBD ithinta kanjani amadoda nabesifazane ngokuhlukile. Lezi zinto zidinga ukucatshangelwa ukuze ziqonde umehluko weqiniso phakathi kwe-IBD emadodeni nakwabesifazane, kodwa ngokuvamile kunzima ukuhlukanisa phakathi nokucwaninga kocwaningo. Kwezinye izimo kucatshangwa ukuthi amadoda nabesifazane bangakhetha ukwelashwa okuhlukile ngoba abesifazane abaneminyaka yobudala abanenkinga bangase babe nokukhathazeka ngokuthi indlela ye-IBD yokwelapha ingathinta kanjani ukukhulelwa . Abesifazane bangase baphoqele ukukhetha ukwelashwa ngemithi uma behlela ukukhulelwa.
Ngaphezu kwalokho, kunezifundo ezithile ezibonisa ukuthi abesifazane abane-IBD bangase baphathwe noma baphathwe ngemithi ehlukene kunamadoda, banama-colonoscopies ambalwa, futhi bangase bangabi namathuba okuphuza imithi njengoba kunqunywe. Kwezinye izimo, kunokukhathazeka ukuthi ukuhlukana okuyisisekelo kwezenhlalo kumadoda nabesifazane kungathinta imiphumela yocwaningo, okwenza isihloko sibe nzima ukutadisha.
Izwi elivela
Isifo sikaCrohn kanye nesifo sofuba esiswini sithinta amadoda nabesifazane ngezibalo ezifanayo kepha kungase kube khona umehluko uma kuziwa ukuthi lezi zifo zithinta kanjani ubulili. Ezimweni eziningi akuqiniseki ukuthi kungani ezinye izinkinga noma ukubonakala kwamathumbu emzimbeni we-IBD kuthinta isondo esisodwa ngokuphindaphindiwe kunokwenza okunye. Nakuba kungasizwisisi ukuthi kungani lokhu kwenzeka, imiphumela yezifundo ezenziwe ku-IBD kwamadoda nabesifazane kungasiza ekuhloleni nasekuphatheni lezi zifo uma kwaziwa ukuthi izinkinga ezithile zivame kakhulu kunesidlangalaleni esisodwa kunomunye.
> Imithombo:
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> García-Gómez E, González-Pedrajo B, Camacho-Arroyo I. "Indima yama-hormone e-sex steroid ekusebenzisaneni kwamagciwane." I-Res Int Res . 2013: 928290.
> Peyrin-Biroulet L, Loftus EV Jr, Tremaine WJ, et al. "Izifo ze-Crohn's Crohn's findings ngaphandle kwe-fistula eqenjini elisekelwe kubantu." I- Inflamm Bowel Dis 2012 2012, Jan: 18: 43-48. Ini: 10.1002 / ibd.21674.
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> Wagtmans MJ1, Verspaget HW, Lamers CB, van Hogezand RA. Ukungezwani kobulili emkhakheni wezokwelapha we-Crohn's disease. " Am J Gastroenterol, 2001; 96: 1541-1546. ini: 10.1111 / j.1572-0241.2001.03755