Ungase ufune ukuba izinso zakho zihlolwe uma uthola ukuthi une-Hep C
Naphezu kwegama layo, lesi sifo esibhedlela i-hepatitis C ("isibindi sesifo sofuba" esibonisa ukuvuvukala kwesibindi), isifo esiningi esihlasela izitho ezingaphezu kwesibindi. Igciwane lesandulela ngculazi elingapheli lingakwazi ukuphazamisa izinhlelo ezincane zomzimba, kuhlanganise nezinso, isikhumba, isimiso se-hematological, ngisho nokudala isifo se-autoimmune nesifo sikashukela. Uma kuziwa ezinso, isifo sofuba C sivame ukuthinta "isihlungi" sezinso, (esibizwa ngokuthi "glomerulus") ngezindlela ezihlukahlukene, ekwakheni izinqubo ezahlukene zezifo.
Lokhu kuqaphela ukuthi i-hepatitis C ingaba nethonya elikhulu ekusebenzeni kwezinso futhi kubangele ukuthi isifo sezinso ngumyalezo obalulekile wokuthatha ekhaya, kokubili udokotela olawula uhlelo lokugula kwesifo sofuba, kanye neziguli. Lisitshela ukuthi iziguli ezine-hepatitis C kufanele zihlolwe ngezinkinga ezingase ziphakamise isifo sezinso. Ngakolunye uhlangothi, iziguli ezethula isazi sezinkanyezi ezinezibonakaliso noma izimpawu ezithile zingase zidingeke ukuba zisebenze ngenxa yesifo sofuba C.
I-Hepatitis C kanye nokulimala kwezinso
Enye incazelo ejwayelekile yokuthi kungani isifo se-hepatitis C sithinta izinso yilona hlangano phakathi kwegciwane lesifo se-hepatitis C kanye nokuthambekela kokuvusa ukuvutha emithanjeni yethu yegazi (okuthiwa "vasculitis"). Lokhu ukuvuvukala kuzovame ukubandakanya izinso futhi kukwazi ukubeka ukusabela okuvuthayo kusihlungi sezinso.
Ngamanye amazwi, ezimweni eziningi, akuyona isifo esiqondile sohlobo lwe-hepatitis C olulimaza umsebenzi wezinso , kodwa empeleni impendulo yomzimba ku-hepatitis C eyenza umonakalo.
Umsebenzi wezinso ungase ube "umonakalo wokubambisana" wempi ehlasela phakathi kwegciwane le-hepatitis C kanye nesistimu yomzimba wethu, kanye neziguli ezihluphekile ezishiye ngezinkinga ezihlukahlukene zezinso.
I-Hepatitis C Yenzani Izinso?
Uma lezi zindlela ezingenhla ziqalisiwe, izinso ziqala ukulimaza.
Indawo engavamile yokulimala yi-filter yezinso, ebizwa ngokuthi i-glomerulus (izinso ngayinye inezigidi zalezi zingxenye ezincane). Isizathu salokhu kwenzeka ngoba lesi sihlungi sibheke ibhola elincane lemithambo yegazi. Njengoba kuphawuliwe ngenhla, igciwane lesifo sofuba lesi-hepatitis C sinomkhuba wokubangela i-vasculitis, ukulimala komzimba emithanjeni yegazi. Ngakho-ke, lokhu kuhlanganiswa kwemithambo yegazi ngaphakathi kwe-glomerulus kufinyeleleke ku-hit enkulu.
Odokotela ngokuvamile bahlukanisa isifo sofuba esihlobene nesifo sofuba kulezi zigaba ezilandelayo:
- I-cryoglobulinemia ehlanganisiwe - lolu uhlobo oluthile lokuvuvukala kwemithambo yegazi / i-vasculitis. Imikhumbi yegazi ingashiswa ezindaweni eziningi, hhayi kuphela ezintsheni. Ngakho-ke, isiguli esithintekile singaba nezimpawu ezivela ezifweni zezinso, ukuya ezinhlungu ezihlangene, ukuqhuma. Uma izinso zithintekile, isiguli singase sibheke igazi emcimbini, futhi udokotela angakwazi ukuthatha amaprotheni (into okungavamile ukuba engekho) kumcibisholo womchamo uma i-glomerulus iye yonakaliswa kakhulu.
- I-Polyarteritis nodosa - ngenkathi ehlotshaniswa nokulimala kwezinso ze- hepatitis B , i-polyarteritis nodosa manje ibikwa futhi nge-infection ye-hepatitis C. Lolu uhlobo oluhlukile lokuvuvukala okukhulu kwezinso zegazi.
- I-nephropathy engenalutho - okungenzeka ukuthi i-hepatitis C ingabangela ukuthi le nhlangano isagcinwa ngokugcwele. Siyazi ukuthi igciwane le-hepatitis B lingenza futhi lokhu kuguqulwa ezintsheni '.
Ngabe Oyedwa Unomphefumulo Wokwazi Ukuthi Ukwazi Yini Ukuba Unesifo Sezinso?
Ungase ungabi njalo! Ngaphandle kwezimpawu ze-hepatitis C, izimpawu ezithile zezinso zingase zibe khona noma zingekho futhi akuyona into engavamile ukuba nesifo esithulile, engazi ukuthi isiguli siyini. Njengoba kuchaziwe ngenhla, iziguli zikwazi ukubona igazi emcimbini, kodwa lokho kungase kungabi njalo njalo. Ngokufanayo, amaprotheni emcimbini angeke abonakale (noma avele njengenhlanhla "emthini emcimbini"), noma kuthiwa kunezinye izifo ongase ube nazo (njenge-hypertension noma isifo sikashukela).
Akudingeki ukuthi, ayikho yalezi zithole ezanele ukuthola noma ukuphikisa ukulimala kwezinso eziphathelene nesifo se-hepatitis C. Kodwa-ke, udokotela omuhle uzokwenza ukuhlolwa kwezinso zezinso ' (njenge-serum creatinine, i-GFR, njll) kwisiguli esinesifo sofuba, kanti isazi sezinkanyezi esilawula isiguli nganoma yiziphi izici ezibalwe ngenhla kufanele ziqale ukubheka i-hepatitis C njengendlela imbangela engaba khona. Ngokuqondile, kunezinye izivivinyo ezimbalwa ezingasiza:
- Ukuhlola okuthile okuthiwa "i- cryoglobulins. "
- Ukuhlolwa kwesici se-Rheumatoid
- Ukuhlola amazinga okuQinisekisa
Njengoba lesi sifo senzeke ezingeni elincane futhi singafika "ama-flavour" ahlukile, i- biopsy yezinso ngokuvamile iyindlela kuphela yokuqinisekisa ukuthi kwenzekani.
Izifo Zezinso Kusuka C Hep C Ukwelashwa
Ngamafuphi, phatha imbangela . Ngakho-ke, kulabo abathola ukuthi banomonakalo omkhulu wezinso okungase kuhlanganiswe ne-hepatitis C, ukwelashwa kufanele kugxile ekwelapheni kwesifo sofuba. Nokho, akuzona njalo njalo. Akuzona zonke iziguli ezine-hepatitis C okuyiwona ozokhethwa ukwelashwa njengoba izinga lokuphendula lihluka futhi imiphumela emibi yokwelapha kufanele igcinwe engqondweni.
Iziguli ezithile zingase zidlulele "iphuzu lokungabuyeli" uma kuziwa kokubili ukulondoloza isibindi noma umsebenzi wezinso. Izinso zivame ukungenawo amandla amaningi okuvuselela. Ngakho-ke, uma ukulimala okunzima kakade kwenzeka kakade ezintsheni, akunakwenzeka ukuthi isiguli singaphilisa umsebenzi wezinso ngisho nangokwelashwa kwesifo sofuba C. Kungakhathaliseki ukuthi, kungaba khona izizathu ezizwakalayo (ngenxa yesibindi nezinye izitho), ukuze uphathe i-hepatitis C.
Iphuzu elibalulekile lokukhunjulwa ukuthi ukutholakala kwesifo sezinso ngokwawo kuguqula ukukhetha kokwelashwa kwesifo sofuba C. Lokhu kungenxa yokuthi ukwelashwa kuvame ukuhluka ngokusezingeni lokulimala kwezinso. Khuluma nodokotela wakho mayelana nendlela engcono yokwelapha.
> Imithombo:
> N Perico, D Cattaneo, B Bikbov, G Remuzzi. I-Hepatitis C Ukutheleleka Nezifo Eziphuthumayo Zama-Renal. CJASN January 2009 vol. 4 cha. 1 207-220.
> Patrice Cacoub, MD. Ukubonakaliswa okungeziweko kwegciwane lesandulela ngculaza elingapheli. I-Adv Adv Infect Dis. 2016 Feb; 3 (1): 3-14.
> Isikhokelo se-HCV: Izincomo zokuhlola, ukuphatha nokuphatha isifo sofuba esibhedlela i-American Association for the Study of Liver Diseases kanye ne-Infectious Diseases Society of America.