Odokotela basebenzisa kanjani i-Procalcitonin Blood Test Test ukusiza ukuxilonga i-Sepsis
I-Procalcitonin (i-PCT) yi- test yegazi eyenziwa kaningi uma kukhona ukusola ukuthi isiguli singase sibe ne-bacteria sepsis , ukutheleleka okukhulu kwe-systemic okungaba yingozi yokuphila. Ukuhlola kwe-procalcitonin kuyindlela eyodwa yokwenza ukuxilongwa ngokushesha futhi kwenzeke londoloza izimpilo.
Ukuhumusha imiphumela ye-Procalcitonin
Ngomuntu onempilo, i-procalcitonin cishe ayinakuphakanyiswa.
Uma umuntu egula, futhi sekusolakala ukuthi i-sepsis, lebhu ye-procalcitonin izodonseka ukusiza ukuthi inqume ukuthi ngabe ukutheleleka kukhona yini. Kubalulekile ukuqaphela ukuthi i-procalcitonin ayihlolisi uhlobo lokutheleleka; Kunalokho, kubonisa ukuthi kungenzeka ukuthi ukutheleleka kungase kube khona. Uma ukuhlolwa kwe-procalcitonin kulungile, udokotela ubheka ubuvivinyo obengeziwe nokuhlolwa kwesiguli ukuze ahlole ukuthi ngabe kukhona yini ukutheleleka, nokuthi uyayiphatha kanjani.
Uma kucatshangwa ukuthi i-sepsis, ukuhlolwa okungeziwe, njengezibalo zegazi kanye nokubala kwegazi okuphelele (CBC) , kuvamise kwenziwa ukuze kunqunywe ukuthi i-sepsis ikhona yini, futhi kunqume ukuthi yiziphi izinto ezibangelwa ukutheleleka. Kwezinye izimo, i-procalcitonin isetshenziselwa ukuhlukanisa phakathi kokutheleleka okukhulu kwendawo, njengokutheleleka kokuphefumula, kanye nokutheleleka okuye kwaba uhlelo.
Ukutheleleka Kwendawo Kwangaphandle Ne-Infection System (Sepsis)
Ukutheleleka kwendawo kunendawo ethile yomzimba; Izibonelo zifaka ukutheleleka kokuphefumula, ukutheleleka kwezinyo noma ukutheleleka kwethambo.
I-Sepsis iyi-infection ejwayelekile eyenziwe ngegazi futhi iyathuthela kuzo zonke izindawo zomzimba. Yize kungenzeka ukuthi ukutheleleka kwendawo kungasongela impilo, isifo se-sepsis cishe sinamandla kakhulu futhi siqinisekisa ukungenelela kwezokwelapha okukhulu.
Imiphumela ye-Procalcitonin
Ngenkathi imiphumela yokuhlolwa kwe-procalcitonin kufanele ihumushe udokotela noma omunye umhlinzeki wezempilo oqeqeshwe, imiphumela ngokuvamile ihunyushwa kanje:
- I-procalcitonin ye-0-.05 μg / L ilindeleke kumuntu onempilo.
- Amazinga we-Procalcitonin angaphansi kuka-.5 μg / L angase akhombise ukutheleleka, kodwa izinga elinjalo alinakwenzeka ukuthi libe nokutheleleka kwesistimu njenge-sepsis. Ukutheleleka kwendawo, njengezinyo ezithathelwanayo noma ukutheleleka kokuphefumula, kungaba khona.
- Izinga le-procalcitonin eliphakathi kuka -5 - 2 μg / L likhombisa ukuthi ukutheleleka kwesistimu kungenzeka, kepha akutholaki ukuhlolwa kwe-sepsis.
- Amazinga we-Procalcitonin ka-2-10 μg / L akhombisa ukuthi kungenzeka ukuthi i-sepsis ingenzeka.
- Imiphumela ye-Procalcitonin ka-10 μg / L noma ngaphezulu ibonisa amathuba amakhulu okuthiwa i-sepsis noma i-septic shock eyinkimbinkimbi futhi ngokuvamile imithi yokwelashwa i-IV kanye nohlobo lwamanzi luqaliswa ngokushesha.
Imiphumela ye-procalcitonin ingasetshenziselwa ukunquma ukuthi ngabe ukutheleleka kungenzeka kubangelwa amagciwane noma igciwane. Uma ukutheleleka kwaziwa ukuba khona, futhi izinga le-procalcitonin liphansi kakhulu, ukutholakala kwama-bacteria akunakwenzeka, futhi kungenzeka ukuthi ukutheleleka kubangelwa igciwane. Lokhu kungavimbela ukusetshenziswa kwama-antibiotics ngokungadingekile, njengoba amagciwane angaphathwa nge-antibiotic therapy.
Ezinye Izimbangela Zokuphakanyiswa Kwe-Procalcitonin
Ngaphandle kwe-sepsis, kunezizathu ezengeziwe zokuthi kungani umuntu angaba nezinga eliphezulu le-procalcitonin.
Ezinganeni, isibonelo, izinga elivamile egazini liphakeme ngaphandle kokutheleleka. Ukulimala - ikakhulukazi ukuhlukunyezwa okukhulu noma ukuhlinzwa - kungabangela nomphumela ophezulu ngaphandle kokuba khona kwe-sepsis. Eminye imithi, ukushuswa akubangelwa yi-sepsis, futhi ngisho nomdlavuza nakho kungabangela ukuphakama emazingeni e-procalcitonin.
Izimo ezinciphisa izinga le-oksijeni etholakalayo ezakhiweni zomzimba, kungakhathaliseki imbangela, zingabangela i-proalcitonin ephakeme uma kungekho ukutheleleka okwamanje. Lezi zingase zivele kusukela ekunciphiseni ukungena kwe-oksijeni ngenxa ye-asthma noma i-pneumonia kuya ekuboshweni komzimba .
Amazinga we-Procalcitonin aphansi noma angenayo i-Sepsis
Kungenzeka isiguli esine-sepsis ukuletha ngezinga eliphansi le-procalcitonin. Uma ukuhlolwa kwenziwa ngokushesha kakhulu ekuguleni, amazinga angase abe aphansi, kodwa cishe azokhuphuka ngaphezu kwamahora ambalwa noma amahora ambalwa alandelayo.
Amazinga aphansi angatholakala futhi uma kungekho mthombo wokutheleleka obala ngokucacile. Lokhu kungase kwenzeke uma ukutheleleka kunzima ukuthola. Isiguli singenaso izimpawu zokutheleleka uma ukuhlolwa kubonisa ukuthi ukutheleleka kukhona.
I-Procalcitonin ne-Sepsis: Kusho Ukuthini Konke?
Empeleni, izinga le-procalcitonin kuphela libikezela ukuthi kungenzeka ukuthi uhlobo lokutheleleka lukhona. Umphumela we-procalcitonin uyisiqondiso, hhayi ukuxilongwa. Cabanga ngomphumela wokuhlola njengesibonakaliso sokuthi ukuhlolwa okunye kufanele kwenziwe, hhayi ukuxilongwa kwangempela.
Iziguli azitholi ukwelashwa ngokusekelwe ezingeni le-procalcitonin yedwa: lonke izinga lempilo yabo yamanje lihlolwa, futhi ukwelashwa kusekelwe esinqumweni somtholampilo odokotela. Isiguli sihlale sihlolwe ngezibonakaliso ezengeziwe nezimpawu zokutheleleka . Ukuze isiguli esihlolwe ekuqaleni kwesikhathi se-sepsis, futhi sinesilinganiso esiphansi se-procalcitonin, ukuphinda ukuhlolwa esikhathini esizayo kungase kubonise ukuthi i-sepsis ikhona.
Ukubaluleka kweqiniso kwezinga lika-procalcitonin ukuthi kungabangela ukwelashwa kwangaphambili kwe-sepsis, okungahle isengozini yokuphila ngokushesha. Ngomuntu othuthukisa i-sepsis, ukuphathwa amahora ambalwa ngokushesha ngenxa yezinga eliphezulu lika-procalcitonin kungenza umehluko phakathi kokugula okuphendula ngokushesha kuma-antibiotic kanye nokugula okunzima ngokwanele ukudinga ukunakekelwa kwezinga le- ICU .
Ngezinye izikhathi kunzima ukubona ukuthi i-Sepsis ixilise ngoba umuntu obhekene nombuzo angase angaqapheli nokuthi banesifo. Into enjengezinyawo ezincane njengomdlali wezinyawo ingaholela ekuthumeni. Kulezi ziguli ezingazi ukuthi isifo, ukuhlolwa kwe-procalcitonin kuyasiza kakhulu.
Imithombo:
> Chakraborty, i-Sutirtha. Ingabe sidinga i-procalcitonin ye-sepsis? Association American for Clinical Chemistry. Iwebhu. > Februwari > 2015.
> Jin, Ming. I-Procalcitonin: Ukusebenzisa emtholampilo yezokwelapha ukuxilongwa kwe-sepsis. I-Lab Med. 2010; 41 (3): 173-177.
Izikhungo zezempilo zikazwelonke. I-procalcitonin ewusizo ekuqaliseni ukwelashwa kwama-antibiotic kumaguli amaningi okunakekela abagulayo. Iwebhu. Mashi 2013.