I-Tachyphylaxis nokubekezela Kunganciphisa Ukuphendula Nge-Insomnia
Amaphilisi okulala angaba u-godsend: ekugcineni ubusuku bokulala ngemva kokuhlupheka nokulala ngenxa yesikhathi eside kakhulu. Kodwa-ke lokhu kukhululeka kungase kube khona isikhathi esifushane, futhi lokhu kungaba umthombo wokukhungatheka nokuphelelwa yisikhathi. Yini eyenza amaphilisi okulala asebenze kangcono ngokuhamba kwesikhathi? Lolu shintsho lungase lubhekane nesimiso sokwenza imithi kubangelwa i- tachyphylaxis . Funda ukuthi i-tachyphylaxis, uhlobo lokubekezela, lingashintsha kanjani ukusebenza kwephilisi yakho yokulala nokuthi yini engenziwa ngayo.
Ukuguqulwa Kokushintsha kwamaphilisi okulala
Kuvamile ukulala amaphilisi ukuze kancane kancane usebenze kahle uma ukwelashwa kuyaqhubeka. Ekuqaleni, imithi inikeza ukuphumula okumnandi: ubusuku bokulala okungaphazanyiswa. Kodwa-ke, kancane kancane imithi ingase ibonakale iqale ukukuhlupha. Akuphumelelanga kakhulu, kungabonakali ukusebenza njengaye okwenzile. Ungathola ukuthi udinga ukwandisa umthamo ukuze uthole umthelela ofanayo. Kunokuba udinga i-tablet eyodwa kuphela, uthatha amabili. Ngesikhathi esiningi, ngisho nalokhu kukhula kwenzalo akubonakali okwanele. Iphilisi lokulala lingase liyeke ukusebenza ngokuphelele. Yini okufanele uyenze futhi kungani lokhu kwenzeka?
Lokhu kwenzeka ngenxa yenqubo yemvelo ebizwa ngokuthi ukubekezela. Nakuba kungase kuzwakale sengathi kuhlobene nokulutha, akudingeki. Eqinisweni, ukubekezelelana kuvame ukuvela ekuphenduleni ukuqhubeka kwemithi. Libhekisela eqinisweni lokuthi ukuvezwa kwemiphumela kuholela ekuphenduleni kancane kancane kumthamo ofanayo.
Cabanga ukuhamba endlini yakho uphuze isinkwa esisha esiphuthumayo kuhhavini. Ngokushesha ngemva kwalokho, cishe awuqapheli ngisho iphunga. Uma uphuma ngaphandle bese uphindela emuva, noma kunjalo, kuzobonakala futhi. Izinga lephunga alishintshi; impendulo yomzimba wakho kuso, noma kunjalo.
Ngendlela efanako, umzimba wakho kancane kancane ungaphenduli kangako umthamo ofanayo wepilisi yokulala.
Lokhu kungahlotshaniswa nemetabolism. I-metabolism yezidakamizwa ixhomeke ku-genetics yakho, ubudala, ubulili, uhlobo lomzimba, nezinye izici. Uma uthatha izidakamizwa ezithile, lokhu kungabangela ukuthi isibindi sakho noma umsebenzi wezinso ukuguqula, okuthinta ezinye imithi kanye. Esikhathini sobuchopho, amangqamuzana omzimba angashintsha inombolo kanye nokuphendula kwe-receptors. Lokhu kunomphumela obalulekile kumthelela wezipilisi zokulala. Ukuze uphendule ngokuqhubekayo emithini, umzimba wakho ungazama ukunciphisa umthelela ngokuthatha ama-receptors asebenzisana nomuthi. Emva kwalokho, nakuba amazinga omuthi angase afane, impendulo ayikho. Ngokuhamba kwesikhathi, iphilisi elilele libonakala liyeka ukusebenza.
Isikhathi sesikhathi salokhu mpendulo siyahluka. Uma kwenzeka ngokushesha, kubizwa ngokuthi i-tachyphylaxis. Uma ihamba kancane, ingase ibhekiswe njengokubekezela. Lokhu akuhambisani neze nomunye umqondo obizwa ngokuthi ukuxhomeka (lapho izinto ezibonakalayo zisebenza ngokomqondo noma ngokomzimba ukugwema ukuhoxiswa noma eminye imiphumela emibi).
Lokhu kudinga kancane kancane ukwandisa umthamo kungaba yingozi uma kungenziwanga ngokusekelwa udokotela wakho. Ngokuyinhloko, ukusebenzisa amaphilisi okulala ngotshwala kungabhubhisa uma ukuphefumula kuthintekile.
Ukuyeka imithi ngokuzumayo kungabangela ukuhluleka kokulala, okuvame ukuphoqa abantu ukuba baqhubeke nemithi yabo esikhathini eside. Lokhu kungaba kuhle ezinkampanini ezidakamizwa ezikhiqiza izidakamizwa, kodwa mhlawumbe zingabonakali kahle kubantu.
Yiziphi Izinketho Ezikhona Zokugwema Tachyphylaxis Nokubekezela?
Ngenhlanhla, kunezinye izinketho zokugwema i-tachyphylaxis nokubekezela ngokusetshenziswa kwamaphilisi okulala. Uma kunokwenzeka, kungcono ukusebenzisa kuphela amaphilisi okulala esikhathini esifushane (ngaphansi kwamaviki amabili). Akufanele usebenzise imithi eminingi ukusiza ukulala kwakho ngesikhathi esifanayo. Ingozi yokudlula ngokweqile, ikakhulukazi ekusetshenzisweni kotshwala, iyinkinga yangempela futhi engase ibulale.
Kufanele ulandele isiqondiso sodokotela wakho futhi uqiniseke ukudalula yonke imithi oyisebenzisayo ukukusiza ukuthi ulale.
Kwezinye izimo, kungadingeka ukwandisa umthamo noma ushintshe kancane kancane kumuthi omusha. Isimo esihle kunazo zonke kungaba ukuphishekela izinketho ezingelashwa ngemithi yokweleleka. Ngokuyinhloko, ukwelashwa kwengqondo-yokuziphatha yokungabi nabuthongo (CBTi) kuye kwafakazelwa ukuthi kuphumelela kakhulu esikhathini eside ukuphulukisa lesi simo. Ayinayo imiphumela emibi, ayikugodli, futhi ayikho ithuba lokubhekana nemiphumela engafuneki yokubekezela kanye ne-tachyphylaxis.
Umthombo:
Katzung, BG Basic & Clinical Pharmacology. I-9th edition, 2004. iphe. 31, 359. I-McGraw-Hill Companies, Inc. eNew York.
Kryger, MH et al . "Izimiso Nemikhuba Yokulala Imithi." I-ExpertConsult , umagazini wesi-5, ngo-2011.