Ucwaningo lubonisa ukuthi lokhu kuyindlela ecacile futhi ephumelelayo
I-Tirosint ingumkhiqizo ohlukile we-levothyroxine ongu-hypoallergenic futhi ufika ku-capelle elithambile.
Kukhona nokwakhiwa kwamanzi kweTirosint, okuthiwa i-Tirosint-Sol, nakuba kungakatholakali ngenxa yokuvunyelwa kwe-FDA yakamuva.
Ukuthuthukiswa kweTirosint
I-Tirosint yenzelwe abantu abane-allergies ezigciniwe kanye nama-dyes atholakalayo amaphilisi e- levothyroxine .
Ama-capelules ama-gel athambile awaqukethe ama-dyes, gluten, utshwala, i-lactose noma ushukela. Eqinisweni, ngaphandle kwe-T4, iTirosint iqukethe ezinye izithako ezingasebenzi ezingamatshumi amathathu: i-gelatin, i-glycerin, namanzi.
Ngaphezu kwalabo abanesifo somzimba, uTirosint itholakale ngokukhethekile ekwelapheni abantu abane- hypothyroidism abanezimo ezithile zokugaya ezifana nesifo se-celiac , isifo se-Crohn, noma isifo se-atrophic gastritis. Ngenxa yezinkinga zokungenwa kwamathumbu emathunjini, lezi zimo zenza amaphilisi amasiko ajwayelekile e-levothyroxine asebenze kangcono-ngamanye amazwi, uTirosint ubonakala edlula izinkinga ze-malabsorption.
Ngendlela efanayo, i-Tirosint inikeza inzuzo kubantu ababheke amaphilisi e-levothyroxine avamile ngokuphazamiseka kokudla kwasekuseni kanye / noma ikhofi yasekuseni.
Eqinisweni, uTirosint ubonakala ebizwa ngokuthi "ukumelana nekhofi" futhi, ngokusho kwabacwaningi, angasetshenziselwa ukufeza izinga le-TSH elilindelekile (nokunakekelwa kwemithi efanele) kubantu abangathandi noma abangakwazi ukushintsha indlela abayithatha ngayo i-levothyroxine yabo.
Kuyathakazelisa ukuthi ngisho nabantu abangaphuzi ikhofi kungakapheli ihora lokuthatha imishanguzo yabo, ukuhlolwa kwe-TSH kubonisa ukuthi abantu bangase bafinyelele ekumameni okungcono usebenzisa i-Tirosint (kokubili ama-capelules gel nesimo samanzi), uma kuqhathaniswa nevothyroxine kwifomu yethebhulethi.
Imiphumela Ebizayo Yomzimba KaTirosint
Ngokwe-Food and Drug Administration, uTirosint ingabangela izinkinga zenhliziyo, kuhlanganise nesilinganiso senhliziyo esanda, ubuhlungu besifuba, nesifo senhliziyo esingajwayelekile, kanye namathambo abuthakathaka noma ahlambulukile.
Ingozi yakho yokuthuthukisa lezinkinga ze-heart kanye / noma amathambo ingase ibe ngaphezulu uma usukhulile noma uthatha kakhulu iTirosint.
Uma unesifo sikashukela, i-Tirosint ingenza kube nzima ukulawula amazinga kashukela egazini. Kulesi simo, udokotela wakho kumele aguqule umuthi wakho wokwelashwa kwesifo sikashukela futhi akuqaphele eduze.
Uma udokotela wakho ebeka uTirosint, qinisekisa ukuthi ubuyekeze yonke imiphumela emibi, futhi unikeze udokotela wakho uhlu lwazo zonke izidakamizwa zakho zamanje, amavithamini, nezithako.
Ukukhonta kweTirosint
I-Tirosint ayikwazi ukuchotshozwa, ukuhlaziywa noma ukusika, kanti amanani atholakalayo ayishumi afaka:
- 13 mcg
- 25 mcg
- 50 mcg
- 75 mcg
- 88 mcg
- 100 mcg
- 112 mcg
- 125 mcg
- 137 mcg
- 150 mcg
Izinhlelo zeTirosint Iziguli
I-Tirosint idayiswa futhi isatshalaliswa yi-Akrimax Pharmaceuticals futhi ikhiqizwa yi-IBSA Institute Biochimique, inkampani ephethwe yedwa, inkampani yezokwelapha e-Lugano, eSwitzerland. Indawo yokuxhumana yase-US ye-Akrimax iseCranford, eNew Jersey.
Uhlelo Lokusiza Abaguli
Uhlelo lwe-Akrimax Patient Assistance Program luyatholakala ezigulini ezihlangabezana nezidingo ezithile zemali engenayo, futhi labo abafanelekayo bangathola i-Tirosint mahhala kuze kube unyaka owodwa, kanye nokuthunyelwa kwenyanga ngayinye kweTirosint ngeposi kuya kweziguli ezifanelekile.
Iziguli zingakwazi ukubhalisa kabusha ohlelweni emva konyaka owodwa wokubamba iqhaza.
Uhlelo oluqondile
Uhlelo lwe-Akrimax Direct lunikeza iziguli ithuba lokugijima ngokuqondile kwe-imeyili yesiguli se-Tirosint. Ikhemisi eliphatha lolu hlelo (Linden Care) lizonquma ukuthi i-copay yakho yomshuwalense noma intengo yemali iyindlela ephansi kakhulu yokukhetha. Lokhu kuhlanganisa ukubaluleka kwekhuphoni iTirosint okwamanje etholakalayo kuTirosint kuwebhusayithi yeTirosint.
Ungathola imithi yakho ngokulethwa okujwayelekile kwe-USPS mahhala (ngokuvamile kuthatha izinsuku ezinhlanu) noma nge-Federal Express ubusuku obubili noma ukulethwa kwezinsuku ezimbili ngezindleko ezengeziwe.
Izwi elivela
I-Tirosint ingase ibe yinto enengqondo kuwe, ikakhulukazi uma ungabeki ukubekezelela noma ukwemukela ama-levothyroxine wendabuko.
Uma ushintsha kuTirosint, qiniseka ukuthi ulandela eduze nodokotela wakho. Ngemuva kokushintsha ama-formulation, kuzodingeka ube nokuhlolwa kwegazi ngemva kwamasonto ayisithupha ukuqinisekisa ukuthi usezingeni elifanele.
> Imithombo:
> Fallahi P et al. Ukuthuthukiswa kokwelapha kwe-Hypothyroidism ne-L-T4 Ukuququza kwamanzi noma i-Capsule le-Gel Soft: Isibuyekezo. Uchwepheshe we-Opin yeDrug Deliv . Ngo-2017 May; 14 (5): 647-55.
> Ukuphathwa Kwezokudla Nezidakamizwa. Ulwazi lokubekezela. I-Tirosint (i-levothyroxine sodium).
> Vita R, Saraceno G, i-Trimarchi F, i-Benvenga S. Ukubunjwa kwe-Novel ye-L-thyroxine (L-T4) Kunciphisa Inkinga ye-L-T4 i-Malabsorption ngeKafesi Egcinwe Ngefomu Lokusebenza Kwethebhulethi Yendabuko. I-Endocrine . 2013 Feb; 43 (1): 154-60.