Ingabe Kukhona Umehluko Phakathi Kwegama Likabizo kanye Nemithi Yezidakamizwa?
Zikhona yini umehluko obalulekile phakathi kwe-generic levothyroxine kanye nezidakamizwa zamagama egama njenge Synthroid, Levoxyl, Unithroid, ne-Levothroid? Yini okufanele uyazi uma ushintsha phakathi kwezinto ezahlukene noma amaphilisi ajwayelekile we-levothyroxine? Ingabe kukhona uphawu oluthile olungcono kakhulu?
Levothyroxine-Incazelo, nokusetshenziswa
I-Levothyroxine inguqulo yokwenziwa (eyenziwe ngomuntu) ye-hormone ye-thyroid eyinhloko (thyroxine, noma i-T4) eyenziwa futhi ikhishwe yi-gland yakho yegciwane.
I-Levothyroxine inqunywe abantu abane-thyroid engasebenzi, isimo esibizwa ngokuthi i-hypothyroidism.
Igama loBrandi kanye nokulungiswa kwe-Generic ka-Levothyroxine
Ungase ujwayelane negama lomkhiqizo kanye nokulungiselela okwenziwe ngezidakamizwa ezahlukene. Amalungiselelo egama lomkhiqizo ngokuvamile atholakala kuqala. Ngemva kwesikhathi, abanye abakhiqizi bavunyelwe ukwenza umuthi ofanayo. Ngenkathi "izidakamizwa" zifana, izithako ezingasebenzi ezingeziwe ukuze kuthuthukiswe ukumuncwa, ukulondoloza imithi, noma ngisho nokwengeza umbala kungahluka.
Kunezinhlobo ezine ezivivinyelwe kahle, igama lomkhiqizo we-levothyroxine etholakalayo e-United States yokwelapha abantu abane- hypothyroidism (i-thyroid engasebenzi) : Levothroid, Levoxyl, Synthroid, ne-Unithroid. Yize kukhona umehluko wokuthi lezi mikhiqizo zakhiwa kanjani, njengokusetshenziswa kombala wama-dyes nama-fillers, ngayinye yale mithi yegama lomkhiqizo inokwethenjelwa.
I-US Food and Drug Administration (FDA) ivume ukusetshenziswa kwe-generic levothyroxine, okwenziwa manje nezinkampani eziningana zezokwelapha.
Umehluko Phakathi Kokuhlelwa Kwamabhayisikili Nama Generic
Abantu bangabona ukuthi abazizwa kahle uma beshintsha kusuka ekulungiseleleni okuya kwesinye, futhi lokhu akumangalisi. Ngenkathi isakhi samakhemikhali lala mithi sinye, kungaba nezindlela eziningana lapho zihluka khona. Isibonelo, lezi zidakamizwa zingase zihluke ku:
- Yeka ukuthi i-levothyroxine ingakanani kuthebhulethi
- Ngakanani levothyroxine engena emzimbeni
- Inani levothyroxine elijikeleza emzimbeni wakho ngemuva kwesilinganiso
- Izidakamizwa ezahlukene zingaba nezindlela ezihlukile
Ngenkathi amanye amakhemikhali afakwe emithini yezidakamizwa ivame ukubhekwa ngokuthi "i-inert" noma "engasebenzi," ucwaningo luye lwathola ukuthi lezi "izidakamizwa" noma izithako ezingasebenziyo ngezinye izikhathi zingadlala indima ekusebenzeni komuthi othile.
Ukushintsha Phakathi Kwezinhlobo Ezihlukahlukene noma Ukulungiselela Okuvamile kwe-Levothyroxine
Uma udokotela wakho ekushintshile egameni legama levothyroxine-njenge-Synthroid-kuya ku-generic version, ungase ubone izibonakaliso zemithi eminingi noma imithi engekho. Eqinisweni, i-American Association of Endocrinologists incoma ukuthi kufanele usebenzise uhlobo olufanayo lomuthi (noma uhlobo olujwayelekile) lwemithi kukho konke ukwelashwa kwakho. Baqhubeka bethi "isifo se-thyroid sidinga ukwelapha impilo yonke futhi sigcinwe kahle ngokuphathwa okuhambisanayo kanye nomuthi ofanayo we-hormone yegciwane."
Ngaphezu kwalokho, unganikezwa ukulungiswa okujwayelekile kwe-levothyroxine njalo lapho une-prescription yakho igcwalisiwe. Ukukhuluma ngokweqile, lokhu kusho ukuthi udokotela wakho angadinga ukwenza ukuhlolwa kwegazi njalo futhi mhlawumbe ushintshe umthamo wemithi yakho.
Nakuba izimpawu zakho zokuzwa i-crummy zingase zenzeke ngokungahambi kahle noma ngenxa yenye inkinga yezempilo, kungenzeka ukuthi umzimba wakho ubhekene nokwahlukana phakathi kwe-Synthroid ne-levothyroxine ejwayelekile. Kubalulekile ukuthi uxoxe ngalezi zinguquko nodokotela wakho.
Kuthiwani Nge-Levothyroxine Yesizukulwane?
Ngokuvamile, ukulungiselela okwenziwe i-levothyroxine kuvame ukuthi kulungile, ucabanga ukuthi unikezwa imithi efana nayo yonke imithi ngokuhamba kwesikhathi. Izinkinga zingase ziphakame uma ikhemisi yakho ihamba phakathi kwamalungiselelo ajwayelekile ajwayelekile kuye ngokuthi yiziphi izindleko eziphansi kakhulu kubo. Ngenxa yalesi sizathu, odokotela abathile banikezela imikhiqizo yegama lomkhiqizo wedwa ukugwema lokhu kudideka.
Uma uzizwa kahle futhi ukuhlolwa kwegazi kwakho kugxilile kwifomu ejwayelekile ye-levothyroxine, ngazo zonke izindlela, qhubeka usebenzisa lokulungiselela. Kungenzeka ukuthi ubhekene nemiphumela ebuhlungu ngokushintsha umkhiqizo wegama lomkhiqizo ngalesi sikhathi ngesikhathi. Kodwa-ke, kungase kudingeke ukuba wenze umsebenzi obhekene nomsebenzi wokuhlola (futhi mhlawumbe ushintshe ama-pharmacy) ukuqinisekisa ukuthi uqhubeka nokulungiselela okufanayo okwenziwe ngumkhiqizi ofanayo.
Umehluko phakathi kwegama lomkhiqizo kanye namalungiselelo ajwayelekile (noma inkinobho phakathi kwalakho) iye yaboniswa ngokucacile nezingane ezine-hypothyroidism ezikhulelwe ezinzima. Singathanda ukuphikisa ukuthi umshini womama wengane oye wathola esikhundleni sokuzalwa kwengqondo ye-hypothyroidism futhi ukhathalela lo mntwana kubaluleke kakhulu.
Yiqiniso okufanayo kungaba yiqiniso uma ushintshwe kumkhiqizo ojwayelekile we-Levothyroxine kuya ku-Synthroid. Iphuzu elibalulekile ukuthi noma yikuphi ukuguqulwa ekwakhiweni kwezidakamizwa ozithatha kungaholela ekushintsheni kulokho umzimba wakho owemukela khona ukusebenza nawo.
Izimpawu Zokwelapha Ukungenakukhululwa Ngu-Levothyroxine Naphezu kwe-TSH evamile
Uma izimpawu zakho ze-thyroid nje zingabonakali ukuthi ziyasabela ekwelapheni, umbuzo wokuqala ozowubuza ukuthi ngabe ubona udokotela ogxile ekuhluphekeni kwegciwane . noma okungenani unesithakazelo esiqinile. Udokotela othakazelayo uzobona ukuthi kunezinhlobo eziningi ze-nuances ekwelapheni, eziningi ezicabangayo ngokucophelela. Uma kungenjalo, kungadingeka ushintshe odokotela noma okungenani uthole umbono wesibili . "Isayizi eyodwa ifaka konke" ukucabanga akusebenzi nezinkinga ze-thyroid .
Kungakhathaliseki ukuthi igama lomkhiqizo noma uhlobo lomuthi we-levothyroxine umuntu owamukelayo, abanye abantu bayaqhubeka bezwa izimpawu ze-hypothyroidism ngisho nalapho i-TSH yabo ijwayelekile. Kwabanye abantu, ukufakwa kwe-T3 kuya ku-T4 "i-monotherapy" kungaholela ekulawuleni kangcono izimpawu kanye nekhwalithi yokuphila. Zibuze le mibuzo uma ukulungiselela kwakho kwe-thyroid kungabonakali okwenzayo.
Ngezansi Ngezinto Ezihlukahlukene Zokulungiselela I-Levothyroxine
Ngenkathi izifundo zingatholi umehluko omkhulu emkhatsini wegama lomkhiqizo kanye nokulungiselela okwenziwe i-levothyroxine, kubalulekile ukuqhubeka nokusebenzisa ukulungiswa owawukusebenzisa (noma ukushintshela kulowo ohlela ukuhlala esikhathini eside) njengoba umehluko ungaba khona. Ukusuka endleleni, isidakamizwa sitholakale emathunjini akho, ukuthi ingakanani imithi amangqamuzana akho "abona," izithako ezingasebenziyo zingadlala indima yakho futhi ekugcineni uzizwa kanjani.
Kungenzeka ukuthi abakhiqizi bemikhiqizo yegama lomkhiqizo bayaziqhayisa ngezinzuzo zemikhiqizo yabo, kodwa izifundo zokwenza usuku zihluleka ukubonisa izinzuzo zokulungiselela olunye phezu kwesinye, okungenani esithombeni esikhulu. Nguwe kuphela owazi umzimba wakho. Uma ungazizwa kahle ekulungiselelweni okujwayelekile noma ngabe ukuhlola kwakho kwegazi kubonisa ukuthi kufanele ube, kungase kudingeke ukushintshe ekulungiseleleni igama lomkhiqizo. Ukuhlola kubheka impendulo kumuthi wabantu abaningi, kodwa abantu abahlali. Kukhona imibiko eminingi ye-anecdotal yabantu abaye batshintsha ukufometha-futhi bazizwe bengcono ngenxa yomshini-ukuxosha noma yikuphi ukungafani ngokuphelele.
Njengombhalo wokugcina, kungenzeka ukuthi uzwile ngemithi yemvelo ekhishwe imvelo . Naphezu kweqiniso lokuthi odokotela abaningi baphazamiseka lapho bezwa ngalezi zidakamizwa, bayasebenza kwabanye abantu. Iphuzu elibalulekile ukuba ngummeli wakho. Nguwe kuphela owazi ukuthi uzizwa kanjani ngokulungiswa kwakho kwe-thyroid, kungakhathaliseki ukuthi igama lomkhiqizo, uhlobo olujwayelekile, i-T3 eyengeziwe noma umkhiqizo okhishwe emvelo. Thola udokotela ozosebenza nawe futhi akulalele, eqaphela ukuthi uzizwa kanjani, kunokuba imiphumela yocwaningo lwamuva, ibaluleke kakhulu.
> Imithombo
- > Carswell, J., Gordon, J., Popovsky, E., Hale, A., no R. Brown. I-Generic neBrand-Name L-Thyroxine ayinayo i-Bioequivalent yezingane ezine-Hypothyroidism eyingozi kakhulu. I-Journal ye-Endocrinology Clinic ne-Metabolism . 2013. 98 (2): 610-7.
- > Kasper, uDennis L .., u-Anthony S. Fauci, noStephen L .. Hauser. Izimiso zikaHarrison zeMithi yangaphakathi. I-New York: Imfundo ye-Mc Graw-Hill, 2015. Phrinta.
- > Romanelli, R., Kimball, V., Dutcher, S., Pu, X., noJegal. Umhlinzeki kanye neziguli ezithintekayo ze-Generic Levothyroxine Ukuchaza: Isifundo esisekelwe e-Electronic Health Records. The Annals of Pharmacotherapy . 2017 Apr 1. (Epub ngaphambi kokuphrinta).