Uke wathola ukuthi uma uthatha imithi yakho ye- Parkinson yesifo ngezinye izikhathi uzizwa ungavinjelwe, ungabe unamandla futhi unamandla kakhulu? Ingabe ukungazifisi kwakho kungakuthola enkingeni? Ingabe umnakekeli wakho uke wabonisa ukukhathazeka ngezinye 'zokuziphatha' zakho zokuziphatha-ukuziphatha ezivela ngemuva kokuthatha imithi yakho ye-PD? Ezinye imithi ye-dopamine esetshenziselwa ukwelapha isifo sika-Parkinson yenza ukuba uhlakulele ukuziphatha okungajwayelekile okubandakanya ukugembula, ukuchitha, ukudla, ukuxhaphaza ngokobulili, nokujezisa.
Izindaba ezinhle ukuthi izinhlobo eziningi zokulawulwa kwengqondo yokucindezela (ICD) zingaphathwa ngokulungisa amazinga wokulinganisa imithi. Kodwa ngezinye izikhathi ukumane nje ukuguqula amazinga e dose akusebenzi. Yini oyenzayo? Ngeshwa, ulwazi oluthile oluqinile lukhona lapho kumaqhinga wokwelapha ama-ICD e-PD ngaphandle kokulungiswa kwemithi. Nazi ezinye iziphakamiso mayelana nokuphathwa kwama-ICD ku-PD etholakala emithonjeni etholakalayo. Khuluma njalo nodokotela wakho ukunquma ukuthi imuphi ukwelashwa okukuhle kuwe.
Ingabe Usengozini Yama-ICD?
Okokuqala, ingabe usengozini engcupheni yama-ICD? Ingabe uthola i- dopamine i-agonist therapy kanye / noma i-levodopa ephezulu? Ingabe ungowesilisa, onomlando wokucindezeleka, umlando womuntu siqu noma womndeni wokuxhomeka kwezinto ezibonakalayo, ubudala obudala ku-PD, noma ekuqaleni kwe-dyskinesia? Xoxa ngalezi zibonakaliso nodokotela wakho bese ubona ukuthi ungakwazi yini ukuthuthukisa uhlelo lokuqapha nodokotela bakho ukuze ukwazi ukubona noma yikuphi i-ICD evelayo ngaphambi kokuba wena nomndeni wakho nikwenze kabi kakhulu.
Uma usengozini engcupheni noma okwamanje uhlangabezana ne-ICD, cabanga ngezindlela ezivamile zokuqonda ukunciphisa umthelela we-ICD njengokuvimbela ukufinyelela kwemithombo yemali, ukuvimbela amasayithi e-Inthanethi afaka ukugembula noma izithombe zobulili ezingcolile; uthengisa kuphela uma isihlobo noma umngane ekhona, futhi uhlanganyele emaqenjini angu-12 wokuzisiza (njengabagembula, ababolekisi, noma abantu abadliwayo abangaziwa).
Ukushintsha Imithi Kungasiza
Buza udokotela wakho mayelana nokushintsha imishanguzo yakho kusuka kolunye uhlobo lwe-agonist ukuya kolunye (okuvela ku-pramipexole noma i-perdid to ropinirole noma kusuka ku-pramipexole kuya ku-per gold),
Uma ukulungisa amanani noma ukushintsha imithi yakho akusebenzi, cela udokotela wakho ngokuzama 'neuroleptic' njenge-haloperidol noma i-pimozide. Lezi zidakamizwa zinciphisa amazinga e-dopamine ebuchosheni futhi zingasiza ukunciphisa i-ICD. Inkinga ukuthi lezi zidakamizwa kanye nokuthiwa yi-antipyychotics e-atypical efana ne-olanzapine ne-risperidone ingase ibe yingozi nakakhulu ye-PD motor function.
Kube khona ubufakazi obuthakathaka bokuthi i-Quetiapine ne-clozapine baphatha ngempumelelo ukugembula okuphathelene nokugula kanye nokucwasana ngokobulili ku-PD. Inkinga ngalezi zidakamizwa ukuthi ibuhlungu kakhulu izimpawu ze-PD motor futhi zineminye imiphumela emibi kakhulu. I-clozapine inobungozi obuncane be-agranulocytosis futhi ingaba yingozi uma ingatholakali ekuqaleni.
Ukukhushulwa kobuchopho obujulile kuye kwaphakanyiswa njengendlela yokwelashwa kwama-ICD ku-PD kodwa kuze kube yimanje, ubufakazi buhlanganiswe ekusebenzeni kwayo kwama-ICD.
Imithombo:
> Isaias IU, Siri C, Cilia R, De Gaspari D, Pezzoli G, Antonini A. Ubudlelwano Phakathi Kokungabi Nesisindo Nokuhlukunyezwa Kokucindezeleka Emgodini kaPasinson. I-Disv Disord. 2008 Feb 15; 23 (3): 411-5.
Lim SY, Evans AH, iMyasaki JM. U-Ann. Ukulawulwa Kwesisusa Nokukhathazeka Okuhlobene Nezifo ZasePasinson: ukubuyekezwa. I-NY Acad Sci. 2008 Oct; 1142: 85-107.
Ukubuyekeza kwe-Weintraub D. I-Dopamine kanye ne-Control Impulse Control in Izifo zikaParkinson. Ann Neurol. 2008 Dec; 64 Ukusekela 2: S93-100.