I-glaucoma ye-Neovascular iyinhlobo ye- glaucoma engabhubhisa kakhulu engabangela ukuphuphutheka uma ingaphathwa kahle. I-glaucoma ye-neovascular ihlelwa njenge-glaucoma yesibili, njengoba ibangelwa ezinye izimo zezempilo. Abantu abaningi abahlakulela i-glaucoma bahlakulela lesi sifo kancane kancane, esikhathini esiyiminyaka. Noma kunjalo, i-glaucoma ye-neovascular ingenzeka ngokuzumayo.
Ubani Osesengozini?
Abantu abasengozini enkulu yokuthuthukisa i-glaucoma ye-neovascular kubandakanya labo abanesifo sikashukela , umfutho wegazi ophakeme, i-cholesterol ephezulu, noma enye inkinga yempilo. Iningi labantu abanama-glaucoma enesifo somzimba basakhulile.
"Glaucoma yezinsuku ezingu-90"
Ngezinye izikhathi i-glaucoma ye-neovascular ibizwa ngokuthi "i-glaucoma yezinsuku ezingu-90" ngoba iqala cishe kwezinsuku ezingu-90 ngemuva kwesinye isenzakalo se-ischemic vascular. Umcimbi we-ischemic vascular umcimbi lapho izicubu zingase zenze ukungabi khona kwegazi ngokuzumayo noma ukukhipha kancane kwegazi kanye ne-oxygen endaweni ethile. Iningi labantu abane-glaucoma ye-neovascular will have one of the events that preceded:
- i-retinopathy esebenzayo yesifo sikashukela
- isifo se-carotid isifo
- i-retinal blood isitsha ukufakwa
- amasosha wokutakula
Ngemva komcimbi we-ischemic, izicubu ngokushesha zilahlekelwa umoya-mpilo. Izisindo ezisesweni lithumela izibonakaliso ukuze zikhule izitsha ezintsha zegazi (inqubo ebizwa ngokuthi i-neovascularization) ngomzamo wokuletha oksijeni nokondla izicubu.
Kodwa-ke, le mishaya yegazi entsha isuke ibuthakathaka futhi ibuthakathaka futhi ijwayele ukuvuza igazi. Le mpendulo iveza izici zamasosha omzimba ezibangela ukuvuvukala.
Ngenxa yokuthi i-backside ye- iris icebile ngemithwalo yegazi, lezi ziqu ezitsha ziqala ukukhula lapho. Imikhumbi emisha ikhula phakathi komfundi futhi ingene engxenyeni engaphambili ye-iris futhi ekugcineni ibe engxenyeni yeso, lapho i- cornea ihlangana ne-iris.
I-angle yeso ihlose imishini yokusebenza, okuyinto ipayipi yokudonsa yezinhlobonhlobo ezihlunga bese igcoba i-intraocular fluid ngaphakathi kweso.
Lezi zitsha ezintsha zegazi kanye nezinye izicubu ezinomzimba zizovala le pipe yokukhipha bese kubangela ukuvalwa kwe-angle. Lapho i-angle ivaliwe, ukucindezeleka kweso kuphakama kakhulu, kubangele umbono obonakalayo nesiso elibomvu, elibuhlungu. Kuthatha cishe izinsuku ezingu-90 ukuze le nqubo ivele-ngakho-ke igama elithi "i-glaucoma yezinsuku ezingu-90."
Ukwelapha Okusheshayo
Ngokushesha, ukwelashwa okunamandla kuyadingeka ukuze ugweme ukuphuphuthekisa. I-glaucoma ye-neovascular iphathwa ngokunciphisa ukucindezeleka kweso ngokushesha futhi kunciphisa ukuvuvukala. Uma ukuvuvukala kwenzeka engxenyeni engaphambili yeso, izicubu ziba nzima, zenze izinkinga eziningi. Lapho nje ingcindezi nokuvuvukala kunciphisa, odokotela abaningi benza isithombe se-pan-retinal (i-PRP). I-PRP yinkinga enkulu ye-retina ye-peripheral ukubhubhisa i-retina ischemic ukuze lezo zimisha zegazi ezintsha ziyeke ukukhula. Lokhu ngokuvamile kubangele ukuguqulwa kwemithambo yegazi. Ngenxa yokuthi i-PRP ibhubhisa ingxenye ye-retina, iziguli kungenzeka zanciphisa umbono we-peripheral . Ngokuvamile, umbono ophakathi uhlala ungaguquki.
Izwi elivela
Izindlela ezintsha zokwelashwa ziqala ukusebenzisa izintatheli zokutakula, eziqukethe izidakamizwa zokulwa nama-antiangiogenic, njenge-Avastin.
Lezi zidakamizwa zishintsha impendulo yesimiso sokuvikela omzimba ukuyeka ukukhula komkhumbi wegazi omusha nokuvuvukala. Izifundo zibonise ukuxazulula okusheshayo kwale mikhumbi kodwa ngezinye izikhathi isimo sizophinde sibuye uma ngabe imbangela engezansi ayibhekiswe. Ngenxa yalokhu, izidakamizwa ze-antiangiogenic zisetshenziswa ngokuhlanganyela ne-PRP. Ngokushesha nje lapho izinkinga zamehlo ziphathwa, imbangela eyinhloko kufanele iqondiswe, ngokuvamile ngesifo sikashukela, isifo somfutho wegazi ophakeme, isifo somswakama we-carotid, noma ezinye izinkinga zamathambo.
Umthombo:
Ukwengeza Ukubuyekezwa Kwe-Optometry, I-Handbook of Ocular Disease Managment, Edition Edition. Glaucoma Neovascular, iphe 36A-38A, 15 Ephreli 2011.