Yiziphi Izinyathelo Ezinhle Zokwelashwa Kwe-Gastric MALT Lymphoma?
Iyini i-gastric MALT lymphoma futhi iphathwa kanjani?
Sibutsetelo
I-Gastric MALT lymphoma uhlobo lwe-non-Hodgkin Lymphoma (NHL) ethinta isisu. Ukuze ufunde kabanzi mayelana nezimpawu nokuhlolwa kwalolu lymphoma, bheka isihloko mayelana neMALT Lymphoma .
Ukwelapha
Lezi zindlela zokwelapha ezilandelayo zingasetshenziselwa izitho zangasese ze-MALT lymphomas:
- Ukwelashwa kwe-Helicobacter pylori ukutheleleka (ama-antibiotics)
- Ukwelashwa kwamafutha
- Ukuhlinzwa
- I-Chemotherapy
Kwezinye izimo, ukuqeda ukutheleleka kwesisu okukhona kungenzeka kube yilokho okudingekile, kanti ukwelashwa okunamandla okuvame ukuvame ukwelapha ngokweqile i-MALT lymphoma. Kulezi ziguli ezinesisindo sokuqala se- H. pylori- esiphezulu se-gastric MALT lymphoma, ukwelashwa kokuqala kwe- H. pylori okulandelwa ukubhekwa kungaba isinyathelo sokuqala ngaphambi kwanoma iyiphi i-radiotherapy. Amaphesenti angaba ngu-20 kuya kwangu-30 iziguli aziphenduli ekuqedeni ukwelashwa noma ukubonisa ukuphindaphinda ngesikhathi sokulandelela, noma kunjalo.
Ama-antibiotics
Eziningi uma zingekho amacala amaningi e-MALT lymphoma esiswini zihlotshaniswa kakhulu nokutheleleka ngeH pylori. I-H. pylori yi-bacterium eyaziwa ukuthi ibangela izidumbu zesisu kanye nezilonda zesisu . Njengoba nje i-bacterium ingalimaza isilonda sokuvikela esiswini kanye namathumbu ukuze kubangele izilonda, kucatshangwa ukuthi kungabangela nokuvuvukala esiswini okungathi kungaholela emdlalweni.
Njengoba cishe isigamu sabantu besimanje segciwane lala mabhaktheriya, ukutheleleka okunjalo kubonakala kungabangela izinkinga kubo bonke abantu, kanti mhlawumbe ezinye izici ezifana nokuzalwa nokuphila okudingekayo, ngokuhambisana nokutheleleka kwe-H pylori, ukudala izinkinga.
Ezigulini ezine-MALT lymphoma ezivivinya ama-H pylori, imishanguzo ye-H pylori ingase ilawule ngokuphelele umdlavuza .
Ezigulini ezingaba ngu-3 kwabangu-4 abanezifo zakuqala, ukwelashwa kwe-H pylori kungabangela ukuxazulula okuphelele kwesisu. Lesi sifo sihlala silawulwa ezigulini eziningi. Labo abanempendulo ephelele bangase bathole ukulandelwa okuqhubekayo, noma ukubhekwa, nge- endoscopies . Naphezu kokuxoxwa okuphelele, abanye abantu bazoqhubeka nokuhlolwa okuhle kwe-PCR ku-H. pylori.
Kutholakale ukuthi abanye abantu abahlola ukungalungi nge-H. pylori ukutheleleka baphendula ekwelashweni ngama-antibiotic nge-remission ephelele, ngakho-ke kungase kuthiwe cishe noma ubani onesisindo somzimba we-MALT lymphoma kufanele aphathwe ngama-antibiotics ukuze aqede uHl. Pylori.
I-Radiation Therapy
I-radiation iyindlela yokwelashwa ye-MALT lymphoma uma uH pylori engekho, noma uma ukwelashwa kwe-H pylori kwehluleka. Kunikezwa ama-radiation aphansi aphansi, futhi lezi zilinganiso cishe zihlale zilawula i-lymphoma. Ukwelashwa kwe-Radiotherapy, yedwa, kungafinyelela izimpendulo eziphelele ezingaphezu kwezi-95% zeziguli , futhi iziguli eziningi zihlala zilawulwa esikhathini eside.
Ukuhlinzwa
Ukwelashwa kuyindlela yokwelapha ngokuphumelelayo kwe-MALT lymphomas yesisu futhi imiphumela yokulawula isikhathi eside ezigulini eziningi. Izingozi zokuhlinza ziphakeme kunezemibala, futhi ngakho-ke ukuhlinzwa akuvame ukusetshenziselwa ukwelashwa.
Njengama-radiotherapy, ukuhlinza ngokuvamile kuvame ukulawula nokuphulukisa i-MALT lymphomas engalinganiselwe esiswini.
I-Chemotherapy
I-Chemotherapy ngokuvamile isetshenziselwa isisu sokuqala esiswini seMALT lymphomas lapho ukwelashwa kwendawo kungakwazi ukulawula izifo, noma uma lesi sifo siphindela. Ukuze uthole ukwelashwa kwesisu esisezingeni eliphezulu, i-chemotherapy iyindlela yokwelapha. Imithi yokwelapha eyahlukene iyasebenza kulezi zithophomas ezikhula kancane.
Immunotherapy
I-rituxan (rituximab) i-antibody yamonoclonal ephumelelayo ezinhlobonhlobo ze-lymphoma kuhlanganise nesisu somzimba we-MALT lymphoma. Njengoba nje imizimba yethu yenza ama-antibodies alwe nama-bacterium kanye nama-virus, i- Rituxan impela "umuntu owenza i-antibody " elwa nokulwa namagciwane omdlavuza.
Njengoba nje ama-antibodies ethu esiqaphela amabonakaliso angavamile ebusweni bama-bacteria, le mithi ibona uphawu oluthile phezu kwamangqamuzana athile abe nomdlavuza.
Ukubhekana nokusekela
Ngokuthakazelisayo, isisu somzimba we-MALT lymphoma ngumdlavuza onokwelapha kakhulu onomqondo omuhle kakhulu. Lokho kusho, ukuthi kungesabisa ukuthi kutholakale ukuthi kunomdlavuza. Ngaphezu kwalokho, ukwelashwa kungahambisana nemiphumela emibi, ikakhulukazi ukukhathala. Finyelela kumndeni wakho nabangani , futhi vumela abantu ukukusiza. Ungahlola futhi lezi zeluleko abantu abaye bazithola bewusizo ekubhekaneni ne-lymphoma .
Imithombo:
UGisbert, J., no-X. Calvet. Ukubukeza isihloko: ukungaqondakali okuvamile okulawulwa kwe-Helicobacter pylori-ehlobene nesisu esiswini se-MALT-lymphoma. I-Pharmacy ejwayelekile kanye Nezokwelapha . 2011. 34 (9): 1047-62.
Nakamura, S., noT. Matsumoto. Isu Lokunakekela I-Lucphoid-Associated Lymphoid Tissue Lymphoma ye-Gastric Gastric. Imitholampilo ye-Gastroenterology eNyakatho Melika . 2015. 44 (3): 649-60.
Nakamura, S., Sugiyama, T., Matsumoto, T. et al. Imiphumela yomtholampilo yesikhathi eside yesikhumba esiswini se-MALT lymphoma ngemuva kokuqothula u-Helicobater pylori: isifundo sokulandelwa kwamalungu angama-429 eJapane. Gut . 2012. 61 (4): 507-13.