I-saline ye-hypertonic engenayo ingenye yezindlela zokwelapha ezintsha zomshoshaphansi we-cystic fibrosis (CF). Iqembu labacwaningi base-Australia lithola izinzuzo ze-hypertonic saline lapho beqaphela ukuthi abagibeli abaphethe i-CF babe nemiphumela engcono kunabantu abaneCF abangazange bangene. Abacwaningi bakholelwa ukuthi ukufaka imfucumfucu yamanzi olwandle usawoti ngesikhathi sokushushumbisa kwakuyisizathu sokuthi abashayeli bezinambuzane babenezinkinga zokuphefumula ezimbalwa kunabalingani babo abangenayo imfucumfucu, futhi isifundo siqinisekisile lokho okutholwe.
Abacwaningi bashicilela imiphumela yocwaningo lwabo ngo-2006, futhi kusukela ngaleso sikhathi, i-hypertonic saline iye yatholakala njengendlela yokwelashwa kubantu abaningi abane-CF.
Kuyini i-Hypertonic Saline?
I-saline evamile iyisombululo samanzi usawoti equkethe uketshezi ofanayo nosawoti njengamanzi ethu emzimbeni. I-saline yama-hypertonic yinoma yisiphi isixazululo samanzi usawoti esiqukethe uketshezi olukhulu kasawoti kunokwenza okune-saline evamile, ngakho-ke ukwanda kasawoti kunamanzi omzimba wethu. Isixazululo esivamile saline ngu-0.9% usawoti. I-salin hypertonic esetshenziswa ekwelapheni kwe-CF i-7% usawoti.
I-hypertonic saline ihlinzekwa kubantu abane-cystic fibrosis kabili nsuku zonke.
Indlela Esebenza ngayo
Ama-flux adlulisa ngaphakathi nangaphandle kwamangqamuzana ngenqubo ebizwa ngokuthi i- osmosis , lapho ukuphuma kwamanzi oketshezi oluthile kunamanzi okugeleza kwekhanda ukuze kuhlangane nama-fluid nge-concentration ekhishwa kasawoti. Ngokusho nje, i-osmosis isho ukuthi amanzi alandela usawoti.
Ngokwelashwa kwe-CF, umshini obizwa nge- nebulizer aerosolizesisombululo se-hypertonic saline. Inkungu ye-saline ifakwa futhi ihlezi emoyeni. Ngenxa yokuthi u-hypertonic saline unolwazi oluningi kakhulu kunoketshezi oluvamile emzimbeni, ludonsa amanzi kusuka kumangqamuzana angena emoyeni. Amanzi axubana ne-mucus obukhulu emoyeni, okwenza kube mncane futhi kube lula ukukhwehlela noma ukuxhuma.
(I-Expectorate iyinhloko yezokwelapha ukukhwehlela ngaphandle.)
Ukucwaninga ukuhlola ukusetshenziswa kwe-saline hypertonic kubantu abane-cystic fibrosis kusikisela ukuthi lokhu ukwelashwa kungase kuholele ekuthuthukiseni okuncane emisebenzini yamapulmoni nokuhlaselwa okuncane noma okukhudlwana. Noma kunjalo, umphumela wezokwelapha uhluka phakathi kwabantu, futhi abanye abantu bangase bathole ukukhululeka okungaphezu kokunye.
Imiphumela emibi
I-hypertonic saline ayiyona imithi, kodwa ibangele ukushintsha emzimbeni okungaba nemiphumela engafanele. Abanye abantu abasebenzisa i-hypertonic saline baye bathola ukwanda kokukhwehlela, ubuhlungu obukhulu bomlomo noma ubuhlungu besifuba obubangelwa ukucasula izicubu.
Akuyona Amanzi Ase-Salt Saline Just? Ingabe Ingenziwa Ekhaya?
Cha. Ukuhlushwa kasawoti kufanele kube okucacile, futhi lokhu kungaba nzima ukufeza isisombululo sokwenza izinto. Okubaluleke nakakhulu, isixazululo kufanele sibe yinyumba ukuvimbela ukungenisa amabhaktheriya angase asongele ukuphila emoyeni.
Imithombo:
> Chesnutt MS, Prendergast TJ. Ukuphazamiseka kwezipulmonary. Ku: Papadakis MA, McPhee SJ, Rabow MW. ama-eds. Ukuxilongwa Kwezokwelapha Nokwelashwa Kwamanje 2016 . ENew York, NY: McGraw-Hill; 2016.
UDonaldson, SH, no-al. "Ukukhishwa kweMucus kanye nokusebenza komfutho ku-Cystic Fibrosis ene-Hypertonic Saline". 2006. I- New England Journal of Medicine 354 (3): 1848-1851. 4 Agasti 2008.