I-Testosterone iyi-hormone ye-androgen eyenziwa yi-correx e-adrenal, i-testes (emadodeni), nama-ovari (kwabesifazane). Ngokuvame ukubhekwa njenge-primary hormone yesilisa yesilisa. I-Testosterone igqugquzela ukuthuthukiswa kwezici zesilisa zobuncane (njengokufana nezinwele zomzimba nokukhula komzimba) futhi kubalulekile ekwakhiweni kwesidoda. Kwabesifazane, i-testosterone idlala indima ekuthuthukiseni amaqanda kanye nokuvuthwa kwamaqanda.
Nakuba i-testosterone ibalulekile kubo bobabili impilo yebesilisa nabesifazane, idlala indima enkulu kunazo zonke kubantu.
Abesilisa abanempilo abaye baphuthunyiswa ukukhulelwa banamaphesenti angama-20 amazinga e-testosterone aqhathaniswa nowesifazane onempilo.
Ukungalingani kwe-Testosterone kungabangela ukungabi nabantwana emadodeni nakwabesifazane. Amazinga aphansi e-testosterone emadodeni angabangela ukungabi namuntu. Amazinga aphezulu e-testosterone kulaba besifazane ahlotshaniswa nokuhlukunyezwa kwabesifazane.
Amazinga e-Testosterone angahlolwa ngokusebenza kwegazi. Lokhu kuvame ukuyingxenye yokuhlukunyezwa kwabantwana nabesifazane.
Incazelo yezolimo
I-testosterone iyimithi ekhulu kakhulu ye-steroid ebizwa ngokuthi i-C19-H28-O2. I-Testosterone nayo yaziwa ngokuthi i-17-beta-hydroxy-4-androstene-3-one.
Incazelo ye-Hormonal Supplementation
I-testosterone ye-prescription isetshenziselwa ukuphatha izimo ezihlobene ne-hypogonadism emadodeni, umdlavuza webele emadodeni, futhi ukubambezeleka kokubeletha kubafana.
I-off-ilebuli, ingasetshenziselwa ukuphatha izimpawu zesikhashana, ukukhathala, nokushayela ucansi oluphansi.
Itholakala njengelesi gel, isisombululo sezinhlayiya, i-patch, umjovo, i-pellet (okufanele ifakwe), noma i-capsule yomlomo.
Amagama omdanso ahlanganisa i-Androderm, i-AndroGel, i-AndroGel Ipump, i-Axiron, i-Depo-Testosterone, i-First-Testosterone, i-First-Testosterone MC, i- Fortesta, i-Natesto, i-Striant, i-Testim, i-Testopel, i-Vogelxo ne-Vogelxo Pump.
Isixwayiso : Ungazami ukwengeza testosterone ngokwakho! Kunezinamba zamawebhusayithi athengisa "izithako ze-testosterone," futhi eziningi zingamanga futhi ziyingozi. Ngisho noma isisindo se-testosterone singokoqobo, akuyona into engenabungozi futhi ingaba yingozi noma ibangele ukungabi nabantwana kumadoda nabesifazane.
Ubufakazi obuningi kakhulu bungabangela ukungasebenzi komuntu.
Izinga Kwabesilisa Nabafazi
Uma ngabe amazinga wakho we-testosterone ahloliwe, ukuhlolwa kwegazi cishe kuzohlelwa ukusa.
Kunezinhlobo ezimbili ze-testosterone ezitholakala egazini lakho:
- I-testosterone yamahhala (eyaziwa nangokuthi i-T free) yi-testosterone engahambisani nanoma yini enye.
- I-testosterone ehlanganisiwe yakha iningi lamazinga akho ephelele we-testosterone. Cishe amaphesenti angu-98 we-testosterone egazini lakho libophezeleke kwelinye lamaphrotheni amabili: i-albin noma i-glomin ebophayo i-hormone (SHBG.).
Uma unamazinga akho e-testosterone ahlolwe, udokotela wakho uzobheka kokubili amazinga wakho wamahhala we-testosterone namazinga akho ephelele we-testosterone.
Amazinga wakho we-testosterone wonke afaka kokubili ama-testosterone mahhala nokuboshwe.
Ingqikithi yamazinga we-testosterone ahluka phakathi nosuku. Ziphakeme kakhulu ekuseni futhi zinciphisa ukuya kusihlwa.
Izinga ezivamile ze-testosterone ngokuyinhloko zithembele kulebhu kanye nokuchazwa kwedokotela wakho.
Ngalokho kusho, nansi amanye amanani ajwayelekile.
Kwesilisa oneminyaka engu-19 noma ngaphezulu:
- Isamba se-testosterone kufanele sibe phakathi kuka-240-950 ng / dL
- I-testosterone yamahhala kufanele ibe phakathi kuka-9-30 ng / dL
Ngomfana oneminyaka engu-19 noma ngaphezulu:
- Isamba se-Testosterone kufanele sibe phakathi 8-60 Ng / dL
- I-testosterone yamahhala kufanele ibe phakathi kuka-0.3-1.9 ng / dL
Okukwenza KuMadoda Nabafazi
Ukuthuthukiswa kwesidoda : I-Testosterone ibalulekile ekukhiqizeni isidoda ku-testes. Kuyinto ibhalansi obucayi, noma kunjalo. Bobabili ubufakazi obuncane kakhulu futhi obuningi kakhulu bungabangela ukubala kwezidakamizwa eziphansi.
Okuhlangene nalokho okubizwa ngokuthi "izici zesilisa eziyisibili": Lokhu kufaka ukukhula komzimba nokuqina komzimba, ukujula kwezwi, ukwakhiwa kwesisindo somzimba, ukuphakama kwesisindo samathambo nokusabalalisa kwamafutha emzimbeni.
Abafana namantombazane abancane banamazinga afanayo e-testosterone. Kuphela ngesikhathi sokukhulelwa ukuthi abafana baqala ukukhiqiza amazinga aphakeme kakhulu e-testosterone, okuholela ekuthuthukiseni izici zesilisa zesilisa ngokobulili.
Abesifazane abanamazinga aphezulu kakhulu e-testosterone bangase babe nezinkinga ngezinwele zobuso kanye nokulinganisa iphathini lesilisa.
Amazinga aphezulu e-testosterone nawo ahlotshaniswa ne-acne emadodeni nakwabesifazane.
Okubalulekile ekuthuthukiseni kwamaqanda emaqanda omzimba : Indlela i-testosterone echaphazela ngayo ukuthuthukiswa kwamaqanda kwabesifazane akucaci ngokuphelele. Enye into ekhona manje ukuthi i-testosterone ivimbela ukufa "ngaphambi kwesikhathi" ngaphambi kokuqala kwentuthuko ye-follicular.
I-testosterone emaqanda ama-ovari nawo angenza ukuthi i-follicles izwele kakhulu i-hormone FSH. I-FSH-echaza i-horlicone-evuselela i-hormone-isisiza ukuvuthwa i-oocyte encane ibe yiqanda elivotshwe.
I-sex drive aka libido : Ukuxhuma phakathi kwe-testosterone ne-sex drive kuyaziwa kakhulu. Amazinga aphezulu we-testosterone enza amazinga aphezulu wesifiso socansi.
Ukwakhiwa kwesisindo somzimba : Amadoda angase akhulise ubuningi besisindo kunabesifazane ngenxa yamazinga aphezulu e-testosterone.
Ukubekezelela ubuhlungu : I-testosterone ingasiza amadoda nabesifazane ukulawula amazinga obuhlungu.
Ukufunda nokukhumbula, ikakhulukazi ukuhlakanipha komhlaba : Izisulu ze-Testosterone ekufundeni nasekukhunjweni. Kuhlotshaniswa ngokukhethekile nokuhlakanipha kwendawo.
Amadoda anezinga elingavamile lokuhlolwa kwe-testosterone ayengozini yokufunda ukukhubazeka.
Ukuzwelana kwengqondo : Ukuzwelana kwengqondo kuhilela ukukwazi ukufunda imizwelo yomunye umuntu ngezwi lomzimba nesimo sobuso, ikakhulukazi ushintsho ngamehlo.
Amazinga aphezulu e-testosterone ahlotshaniswa nekhono eliphansi lokufunda abantu. Abesifazane ngokuvamile baphumelela emadodeni ekuvivinyeni ukuzwelana kwengqondo. Inkolelo yokuthi amazinga aphansi e-testosterone yisona sizathu sokuthi abesifazane bangcono kulekhono.
Imithombo:
Camacho EM1, Huhtaniemi IT, O'Neill TW, Finn JD, Pye SR, Lee DM, Tajar A, Bartfai G, Boonen S, Casanueva FF, Forti G, Giwercman A, Han TS, Kula K, Keevil B, Pendleton N, Punab M, Vanderschueren D, Wu FC; I-EMAS Group. "Izinguquko ezihambisana nobudala emisebenzini ye-hypothalamic-pituitary-testicular kumadoda asekhulile namadala asetshenziselwa ukuguqulwa kwesisindo nezindlela zokuphila: imiphumela ye-longitudinal evela e-European Male Aging Study. "I-Eur J Endocrinol. 2013 Feb 20; 168 (3): 445-55. i-doi: 10.1530 / i-EJE-12-0890. Phrinta ngo-2013 Mar.
I-Kolettis PN1, i-Purcell ML2, iParker W3, i-Poston T2, i-Nangia AK3. "I-testosterone yezokwelapha: imbangela ye-iatrogenic yokungabi nabesilisa kanye nenkinga ekhulayo." Urology. 2015 Meyi; 85 (5): 1068-72. i-doi: 10.1016 / j.urology.2014.12.052. I-Epub 2015 Mhlaka 25. http://www.ncbi.nlm.nih.gov/pubmed/25819620
Samplaski MK1, Loai Y1, Wong K1, Lo KC2, Grober ED1, Jarvi KA3. "Ukusetshenziswa kwe-testosterone kubantu abesilisa abangenalutho: ukubeka amaphethini kanye nemiphumela emigqeni yezinja kanye nama-hormonal. "Fertil Steril. 2014 Jan; 101 (1): 64-9. i-doi: 10.1016 / j.fertnstert.2013.09.003. I-Epub 2013 Oct 2.
I-Spritzer MD1, iDaviau ED, iConeeny MK, i-Engelman SM, i-Prince WT, i-Rodriguez-Wisdom KN. "Imiphumela ye-testosterone ekufundeni kwendawo nasenkumbulweni kumagundane amakhulu amadoda. "Horm Behav. 2011, 59 (4): 484-96. doi: 10.1016 / j.yhbeh.2011.01.009. Epub 2011 Feb 2.
I-Surampudi P1, i-Swerdloff RS, i-Wang C. "Ukubuyekezwa kwindlela yokwelapha yesilisa." Uchwepheshe we-Opin Pharmacother. 2014 Jun; 15 (9): 1247-64. i-doi: 10.1517 / 14656566.2014.913022. Epub 2014 Apr 23. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC4168024/
I-testosterone: Ulwazi lwezidakamizwa. I-Lexicomp, Inc. I-UptoDate.com.
I-ID yokuhlola: TGRP; I-Testosterone, Ingqikithi neseFree, iSerum. I-MayoClinic Medical Labatatories.
van Honk J1, Schutter DJ, Bos PA, Kruijt AW, Lentjes EG, Baron-Cohen S. "Ukuphathwa kwe-Testosterone kwenza kube nzima ukuqonda ukuqonda kwabesifazane ngokuya kwesilinganiso sesibili kuya kwesine. "UMt Natl Acad Sci US A. 2011 Feb 22; 108 (8): 3448-52. doi: 10.1073 / pnas.1011891108. Epub 2011 Feb 7.
Wu FC1, Tajar A, Pye SR, Silman AJ, Finn JD, O'Neill TW, Bartfai G, Casanueva F, Forti G, Giwercman A, Huhtaniemi IT, Kula K, Punab M, Boonen S, Vanderschueren D; Iqembu lase-European Aging Study Aging. Ukuphazamiseka kwe-hypothalamic-pituitary-testicular kumadoda amadala kuxhumene ngokulingana nobudala kanye nezimo eziyingozi ezingaguquguqukayo: Isifundo Se-Male Aging saseYurophu. "J Clin Endocrinol Metab. 2008 Jul; 93 (7): 2737-45. i-doi: 10.1210 / jc.2007-1972. Epub 2008 Feb 12.