Uhlobo Lwe-Arthritis Ngokuvamile Lungaqondakali njengeGout
I-calcium pyrophosphate disease deposition (CPPD) uhlobo lwe-arthritis. Kubangelwa ukufakwa kwamakhekhedi e-calcium phosphate emahlanganisweni futhi kunezici ezifanayo kumuthi. Ukuhlaselwa kwe-CPPD kungenzeka ngokuzumayo futhi kubangele ubuhlungu obukhulu, ukuvuvukala nokukhubazeka.
I-CPPD yaziwa ngamanye amagama afaka ukuhlaziya , igama elidala lisasetshenziswa emikhakheni eminingi yezokwelapha, ne- chondrocalcinosis , ekhuluma ngokuqondile ngemali ye-calcium ekhulayo ezindaweni ezihlangene.
Izimpawu
Nge-CPPD, ukubunjwa okuqhubekayo kwe-calcium emajoyini kungabangela ukuphazamiseka kwesinye isikhathi sempawu zamathambo ezinokuvutha kuhlanganise nobuhlungu, ukuqina, ukuvuvukala, ukukhathala, umkhuhlane wezinga eliphansi, nokuvinjelwa kokunyakaza.
Ingozi yokuhlaselwa kwe-CPPD ivame ukwanda ngeminyaka. Ngokwezibalo ezivela e-American College of Rheumatology, ukuthuthukiswa kwamakristalu e-calcium kwenzeka cishe amaphesenti amathathu abantu abadala eminyakeni yawo-50. Leli nani likhuphuka libe ngamaphesenti angu-50 ngesikhathi umuntu efinyelela ku-90.
Akuwona wonke umuntu owenza i-CPPD crystal izobona izimpawu. Ezingamaphesenti angu-25 abenzayo, iningi lizoba neziqephu ezibuhlungu ezibandakanya amadolo noma ukuzwa ubuhlungu nokuvuvukala ama- ankle , izimbambo , izandla , izigqoko , noma amahlombe . Ukuhlaselwa kwe-CPPD kungadlulela ezinsukwini ezimbalwa kuya emavikini amaningana.
Ukuhlaselwa kwe-CPPD kungase kubangelwe ukugula okukhulu, ukuhlinzeka, ukuhlukunyezwa, noma ukucindezeleka ngokweqile. Phakathi neminyaka, lesi sifo singabangela ukuwohloka kwamalungu okuqhubekayo, okuholela ekukhubazekeni kwesikhathi eside.
Cishe amaphesenti amahlanu alabo abagulayo bazoba nesifo samathambo esihlala njalo-njengesimo esithinta amalunga omzimba (okusho amalunga afanayo ezinhlangothini ezahlukene zomzimba, njengama-wrists noma amadolo).
Ukuxilongwa
Ukuxilongwa kwe-CPPD kuvame ukulibaziseka ngoba izimpawu zivame ukuphutha ngamanye ama-arthritis kuhlanganise ne- osteoarthritis , i-arthritis ye-rheumatoid, ne-gout (isifo esibonakala ekwakheni ama-crystals e-uric acid).
Ukuxilongwa kuzovame ukufaka isifiso soketshezi oluhlangene oluhlangene kanye nokuhlaziywa kwe-crystalline deposits ebhodini.
Udokotela angase futhi ahlele ukucabangela ukuhlolwa okufana ne-ultrasound, ukuskena kwe- computed tomography (CT) , noma ukukhipha i-imaging magnetic resonance (MRI) ukusiza ukukhomba izibalo ezihlanganisiwe ezungeze ukujoyina.
Ukwelapha
Ngokungafani ne-gout, lapho ama-crystals e-uric acid angaqedwa ngayo ngemithi, amakristalu afaka phakathi i-CPPD engenayo i-insoluble (okusho ukuthi ayikwazi ukuchithwa).
Ngakho-ke, ukwelashwa kugxile ekunciphiseni izimpawu nokugwema ukuhlasela okuzayo. Izinketho zokwelapha zihlanganisa:
- Izidakamizwa ezingezona ukuvuvukala (non-steroidal anti-inflammatory drugs) (NSAIDs) ukulawula ubuhlungu nokuvuvukala
- Ama-Colcrys aphansi (i-colchicine) , evame ukusetshenziswa ku-gout, kubantu abangakwazi ukubekezelela ama-NSAID
- I-Cortisone (i-steroid) imijovo engxenyeni ethintekile ukuze inikeze ukukhululeka okwesikhashana, okwesikhashana kokuvuvukala
- I-plaquenil (i-hydroxychloroquine) noma i- methotrexate (i-MTX) ezimweni ezimbi kakhulu ukukhubaza impendulo yomzimba nokunciphisa ukuvuvukala
Ukuhlinzwa kungacatshangwa ukususa ubuningi obubalwe kusukela ekuhlanganyeleni, nakuba kusacatshangwa ukuhlolwa ngedatha elinganiselwe ukusekela ukusetshenziswa kwayo.
> Imithombo:
> I-American College of Rheumatology. "I-Calcium Pyrophosphate Deposition (CPPD)." I-Atlanta, Georgia; ibuyekeziwe ngoMashi 2017.
> Schlee, S .; I-Bollheimer, L .; Bersch, T. et al. "I-Crystal Arthritides: I-Gout ne-Calcium Pyrophosphate Arthritis / Ingxenye 1: I-Epidemiology ne-Pathophysiology." I-Gerontol Geriatr. 2017. INGABE: 10.1007 / s00391-017-1197-3.