Izinto eziyi-8 eziphakamisa i-Platelet Count yakho

Ngokuvamile, inani leplatelet elingaphezu kuka-450,000 amaseli nge-microliter libhekwa liphakeme; lokhu kwaziwa ngokuthi thrombocytosis. Kunezimbangela eziningi ze-thrombocytosis futhi ngenhlanhla, iningi liyingozi futhi ihamba kancane. Ake sihlole ezinye zezimbangela ezivame kakhulu.

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Izinkinga ze-Myleoproliferative

Izifo ezingapheli ze-myleoproliferative (isifo lapho umnkantsha wesenza amangqamuzana amaningi egazi) kungabangela i-thrombocytosis. Lokhu kuhlanganisa i- polycythemia vera , i-thrombocythemia ebalulekile (ET), kanye ne-myelofibrosis eyinhloko.

E-ET, ngokwesibonelo, umnkantsha wamathambo wenza ama-megakaryocytes amaningi, amangqamuzana enza amaplatelethi, okubangelwa i-thrombocytosis. Ngalezi zimo, izinombolo eziningi kakhulu zamaplatelets zenza igazi libe likhulu futhi ligele kancane kancane elingabangela ama-blood clots. Ukwelashwa kuhloswe ukunciphisa inani leplatelet ukunciphisa le ngozi.

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Ukutheleleka

Kuzo zombili izingane kanye nabantu abadala, ukutheleleka kuyimbangela evamile kakhulu yokubalwa kweplatelet. Lokhu kuphakama kungaba okudlulele, nge-platelet kubalwa ngaphezulu kwesigidi esisodwa samaseli nge-microliter ngayinye.

Iningi labantu ababhekana nalokhu liyinkimbinkimbi kodwa iqembu elincane leziguli ezinezinye izingozi zingase zithuthukise ama-blood clots. I-platelet ibalwa ngokuvamile ibuyela emuva evamile ngemva kokuxazulula ukutheleleka, kodwa lokhu kungathatha amasonto amaningana. Kwezinye iziguli, i-thrombocytosis ingaba nomphumela ovukelayo ngemuva kokuba ne-thrombocytopenia (amaplelet aphansi) ngesikhathi sokutheleleka kokuqala.

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Ukwehla kwe-Iron Anemia

Nakuba i-hemoglobin ephansi namangqamuzana amancane egazi abomvu yiwo amanani ajwayelekile e-laboratory ahlobene nokuntuleka kwensimbi ye-anemia, ukuphakama kwenani leplatelet akuyona into engavamile. Ngalesi sikhathi, aziwa ukuthi yini ngempela ebangela le thrombocytosis. Ngokuvamile, kuvunyelwe kahle futhi ixazululwa ngezokwelapha ezifanelekayo zokwengeza.

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Ukungabi nePeni

Inani elithile lamaplatelet lihlala endaweni yethu ngesikhathi esithile. Uma i-pengu isuswa ngokuhlinzwa (i-splenectomy) noma iyeka ukusebenza kahle (i-functional asplenia) njengesifo se-sickle cell, imiphumela ye-thrombocytosis. Le thrombocytosis ivame ukuba mncane ukulinganisa nokubekezelela kahle.

Ngokushesha ngemva kwe-splenectomy, i-thrombocytosis ingaba yinkimbinkimbi futhi ingabangela ukubunjwa kwegazi. Le nkinga yokulandelela i-post-splenectomy ivela cishe ngamaphesenti angu-5 weziguli. Ngokuvamile, ingozi inkulu kakhulu ngenyanga ngemuva kwe-splenectomy.

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Imibandela yokuvuvukala

Izimo ezine-inflammation ezifana ne-rheumatologic disorders, isifo sofuba esibulalayo, kanye ne-vasculitides ingaba ne-thrombocytosis. Ukubalwa kweplatelet ephakeme kwenzeka ekuphenduleni ama-cytokines (amaprotheni amancane akhishwa emaseli asho amanye amaseli ukuthi enze okuthile). Ngokuyinhloko, i-cytokines interleukin-6 ne-thrombopoietin ivuselela ukukhiqizwa kweplatelet.

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Cryoglobulinemia ehlanganisiwe

I-cryoglobulinemia ehlanganisiwe ingabangela ukuphakama okungamanga ku-countlet count. Kule nkinga, ama-cryoglobulins (amaprotheni) egazini abambe ndawonye lapho evezwa emazingeni ashisayo (njengezandla nezinyawo). Lezi zinhlayiya zingabizwa ngamanga njengamaplatelets ngomshini owenza inani eliphelele legazi . Lesi simo sihlobene nokutheleleka kwesifo se-hepatitis C, i-systemic lupus erythematosus, nesifo se-rheumatoid arthritis.

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I-Hemolytic Anemia

Uma i-hemolytic anemia (i-anemia eseceleni kwesibomvu segazi elibomvu) ibangela ukwakheka kwamaseli abomvu abomvu kakhulu, lawa maseli abomvu angase ahlolwe ngokungafanele njengama-platelets ngomshini owenza inani eliphelele legazi. Lokhu kungatholakaliswa ngokubukeza i-blood smear ye-peripheral (i-slide ye-microscope yegazi). Inani elibukwayo lamaplatelet lizobe liphansi namaseli amancane amancane egazi abonakalayo.

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Ukulimala

I-Thrombocytosis ingaba nomphumela wesibili wezinye izifo ezimbi (umdlavuza). Lokhu kwaziwa ngokuthi i-thrombocytosis ye-paraneoplastic. Lokhu kuvame kakhulu emathunjini aqinile njengomdlavuza wamaphaphu, i-hepatocellular (isibindi) carcinoma, umdlavuza wama-ovari, nomdlavuza we-colorectal. Ukubalwa kweplatelet ephakanyisiwe kungabonakala naku- lemonemic myelogenous (CML) engavamile .