I-Symptom Ejwayelekile Ixoxa Ngokuvamile
Ukukhathala kuyathinta kakhulu abantu abane-rheumatoid arthritis (RA). Abantu abaningi bayazi ukuthi i-RA ihlotshaniswa nobuhlungu obuhlangene nokuqina okuhlangene . Ngokwephutha, abantu bacabanga ukuthi kutholakala kalula kunamalungu noma ngaphezulu okuthintekile okubangelwa ukulinganiselwa ngokomzimba. Iqiniso liwukuthi, i-RA yisifo sesistimu , okusho ukuthi lesi sifo sithinta wonke umzimba, hhayi nje amalunga.
Lokhu kwenzeka ngezinhlobo eziningi zokuvuvukala kwe-arthritis noma ezinye izifo ezivuthayo.
Naphezu komthelela walo kubantu abane-RA, ukukhathala kuyimpawu engabonakali, okwenze kube nzima ukuchaza, ukuxoxa noma ukuxazulula. Ukwengeza kulokho ukuhluka kokukhathala-kuyahlukahluka komuntu kumuntu kanye nangomuntu ngamunye. Ngokusho kwe- arthritis Research and Therapy (2015), ukukhathala kuyinkinga yamaphesenti angama-40 kuya kwangu-80 abantu abane-RA noma i- spondyloarthritis . Ukukhathala kunzima ngamaphesenti angu-75 weziguli ezine-spondyloarthritis nama-50 amaphesenti alabo abane-arthritis ye-rheumatoid.
Ukukhathala Ku-Arthritis Ye-Rheumatoid Kuchazwe Kanjani?
Ukukhathala kuyisimo sokukhathala okuhambisana namandla, ukwehluleka, ukukhathazeka, ukucasula nokulala. Kukhona nesici sokucabanga, ngakho ukukhathala kungaphezu kokukhathala okulula abantu abaningi ababhekana nakho. Ngokukhathala okujwayelekile, isikhathi sokuphumula sanele ukululama.
Kodwa nge-RA noma ezinye izifo ezivuthayo, ukuphumula akukwanele ukuletha ukutakula ekukhatheni okuhambisanayo.
Yini Ebangelwa Ukukhathala E-Rheumatoid Arthritis?
Inhlangano eyaziwayo ikhona phakathi kokukhathala nobuhlungu. Amazinga aphezulu obuhlungu ahambisana nezinga eliphezulu lokukhathala. Ukuhlangana phakathi kwesifo sesifo nokukhathala, noma kunjalo, akusekelwe kahle ezincwadini zezokwelapha.
Abacwaningi bacabanga ukuthi ukukhathala ku-RA kuyinhlangano ehlukahlukene. Nakuba ukukhathala okuhambisana ne-RA kungase kuhlobene nezici ezithile zezifo, kufaka phakathi ubuhlungu, ukuvuvukala , umsebenzi wesifo, nokulimala okuhlangene, kungase kuhlotshaniswe nezici zomsebenzi womzimba, njengokukhubazeka, izinga lempilo elihlobene nempilo, kanye nekhwalithi ukulala. Kungase kube nobudlelwane nezinkinga ezingqondweni noma ezingokomzwelo, futhi, njengokucindezeleka noma ukukhathazeka. Ezinye izici, kuhlanganise nobudala, ubulili, noma isimo somsebenzi kungasiza.
Ekubuyekezeni izifundo ezacatshangelwa ukuthi imbangela yokukhathala ku-RA, enyatheliswa ku- Arthritis Care and Research ngo-2013, iningi lathola inhlangano phakathi kobuhlungu nokukhathala. Izifundo ezimbalwa azizange, mhlawumbe ngenxa yokutadisha. Umsebenzi wokuvuvukala , njengoba kuboniswe isilinganiso se-sedimentation noma i- DAS28 , akubonanga ukuhlangana okucacile nokukhathala ku-RA. Ngezici zomuntu siqu, ubude besikhathi umuntu ayenayo i-RA babonakala behambisana nokukhathala. Ukusebenza ngokomzimba nokukhubazeka, kanye nekhwalithi yokulala, zitholakale zihambisana nokukhathala ku-RA. Ukucindezeleka kwakuyisici esibalulekile ezifundweni eziningi ezazibheka imbangela yokukhathala ku-RA.
Ngakho-ke, kubonakala sengathi ayikho imbangela eyodwa, ebonakalayo yokukhathala ku-RA.
Kungenxa yezici ezithintekayo nezingaphansi, cishe okubandakanya ubuhlungu, ukukhubazeka (ukwehla ukusebenza komzimba), nokucindezeleka.
Ingabe I-Rheumatologists Ikheli Lokukhathala?
Iziguli eziningi azikhulisi ukukhathala lapho zivakashela i- rheumatologist , mhlawumbe ngoba zicabanga ukuthi ziyingxenye yesifo nokuthi lokho okuncane kungenziwa. Ngokusho kwemiphumela yocwaningo eshicilelwe ku- Clinical Rheumatology ngo-2008, kanti iningi labahlengikazi banomuzwa wokuthi ukukhathala kufanele kuqondiswe ngisho nalapho ubuhlungu bulawulwa kahle, abaningi banomuzwa wokuthi abanye ochwepheshe bezokwelapha baphathelene nakho. Imiphumela yocwaningo yembula ukuthi amaphesenti angama-72 ama-rheumatologists akhuluma ngokukhathala ngesikhathi sokubonisana kokuqala kwesiguli, kuyilapho lokho kwehla kwamaphesenti angu-33 ukubonisana okulandelayo.
Ukukhulumisana okungcono mayelana nokukhathala, okwenziwe kokubili ngesineke nodokotela, kuyadingeka ngokucacile.
Yini Engenziwa?
Ngokombono wezokwelapha, ukunciphisa ukuvuvukala ku-RA noma ezinye izifo ezivuthayo kunganciphisa ubuhlungu nokukhathala. Amazinga ayenayo we- cytokines (i-IL-1, i-IL-6, i-TNF-alpha) engakhudlwana ingabandakanyeka, ngakho ukulawula ukuvuvukala kuyinto ebaluleke kakhulu.
Imithombo:
Repping-Wuts et al. Ulwazi lwe-Rheumatologists, isimo sengqondo ukuphathwa kwamanje kokukhathala kweziguli ezine-arthritis ye-rheumatoid (RA). I-Rheumatology yezokwelapha . 2008; 27: 1549-55.
Louati et al. Ukukhathala ukuvuvukala okungapheli - ukuxhumanisa emigwaqweni yobuhlungu. I-Arthritis Research & Therapy . 2015; 17: 254.
Nikolaus et al. Ukukhathala Nezici Ezihlobene Nokukhathala E-Rheumatoid Arthritis: Ukubuyekezwa Okuhlelekile. Ukunakekelwa kwe-Arthritis Nokucwaninga . 2013; I-Vol. 65. 1128-1146.
I-Pollard LC et al. Ukhathala ku-arthritis ye-rheumatoid kubonisa ubuhlungu, hhayi umsebenzi wesifo. I-Rheumatology (Oxford) ka-2006; 45 (7) 885-889.
U-Wolfe F et al. Ukukhathala, i-rthmid arthritis, kanye ne-anti-tumor necrosis factor therapy: uphenyo kwiziguli ezingu-24 831. Journal of Rheumatology . 2004; 31 (11): 2115-2120.