Ingabe i-Gluten-Free Diet isebenza kahle eG Gluten Ataxia?
Ngombono, kufanele ukwazi ukuphatha izinkinga ze- gluten ataxia ngokuqeda i-gluten ekudleni kwakho.
Ukucwaninga okwenziwayo kwi-ataxia ye-gluten (ikakhulukazi uDkt. Marios Hadjivassiliou, isazi sezinzwa zezokwelapha eRoyal Hallamshire Hospital eSheffield, eNgilandi owaqala ukucwaninga umqondo we-gluten ataxia) kubonisa ukuthi lokhu kungaba yiqiniso - ungase ukwazi ukuvimba umonakalo wakho uhlelo lwezinzwa ngokulandela ukudla okunamandla okungenalutho kwe-gluten .
Noma kunjalo, okungenani isifundo esisodwa esisodwa esenzelwe iziguli ezine-alexia esicatshangelwayo-ayifuni emuva lokhu - ayizange ithole ukuthuthukiswa okuphawulekayo kwezimpawu ze-ataxia ezigulini ezilandela ukudla okungahambisani ne-gluten (nakuba idatha idinga kuleso siqondiso).
Inkolelo kaDkt. Hadjivassiliou ukuthi ukudla kudinga ukuqina kakhulu ukuze kube nemiphumela emihle kulezi zinkinga zezinzwa. Lokho kuhilela ukukhipha ukulandelela okuningi kwe-gluten ngangokunokwenzeka kanye nokudla okwebala okune-gluten.
Le mbono - ukuthi udinga ukuqeda ukudla kwakho ngokuphelele kwe-gluten, ngisho nokulandelana kwe- gluten okuvame ukutholakala ekudleni okungenalutho olubhalwe nge-gluten - kusekelwa yi-imibiko ye-anecdotal yabantu abane-gluten ataxia nezinye izimo ze-neurological. Lezi zimpawu ze-neurological ezihlobene ne-gluten kubonakala kuthatha isikhathi eside kunokuthi izimpawu zesisu ziphuthumise, futhi kubonakala sengathi ziba ngcono ekudleni okungenayo i-gluten.
Kodwa-ke, akukho ucwaningo lwezekwelapha njengalokhu lusazokwakha le ncazelo, ngakho-ke akuwona wonke odokotela abathengela emcimbini wokusebenzisa ukudla okungenalutho kwe-gluten ukuphatha i-ataxia.
I-Gluten Ataxia ibonisa ukuphendula okuzenzakalelayo ku-Gluten
I-gluten ataxia ibonakala ngokulimala kwangempela kobuchopho okuholela ezinkingeni nge-gait, imilenze, namehlo akho.
Umonakalo uqhubeka, futhi izimpawu zesifo ngokuvamile zibonakala phakathi neminyaka engama-50s, ngokusho komqulu ovumelanisiwe oshicilelwe ngo-2012 oshicilelwe ku- BMC Medicine .
Izimpawu zihlanganisa ukungaqiniseki ezinyaweni zakho, ukuxuba, nezinkinga zokuhamba, izinguquko ezinkulumweni nokubunzima ukugwinya. Ukuxilongwa kuyinkimbinkimbi njengoba kungekho isifo sezokwelapha esamukelekayo se-gluten ataxia.
Nakuba kungenjalo bonke odokotela bavumelana ngokukhona kwe-ataxia ye-gluten, idokhumenti yokuvumelanisa ichaza isimo njengendlela yokusabela ngokuzenzakalelayo ku-gluten "emndenini" ofanayo njengesifo se-celiac (okubandakanya amathumbu amancane) kanye ne- dermatitis herpetiformis (okubandakanya isikhumba).
Ingabe Ukudla Okungenayo I-Gluten Kungasiza Gluten Ataxia?
Izifundo ezimbili kuphela zibuke imiphumela yokudla okungenayo i-gluten kuphela ezigulini ezingasebenzi. Omunye waphetha ngokuthi ukudla kuyasiza ekunciphiseni izimpawu zezinzwa, kuyilapho enye iphetha ngokuthi ubufakazi obunjalo bungenakho.
Esifundweni sokuqala, esenziwa uDkt. Hadjivassiliou kanye nosebenza nabo, abacwaningi babheka imiphumela yokudla okungenalutho kwe-gluten kubantu abangu-43 abane-gluten arixia etholakalayo. Ezinye zalezi ziguli zine- atrophy ephawulekayo etholakala esibhedlela se-celiac kanti abanye abazange bakwenze, kepha ukudla kwabonakala kubasiza wonke umuntu owalandela ngokuqinile.
Kulolu cwaningo, iziguli ezingu-26 zihambisana ngqo nokudla, njengoba kuboniswa imiphumela emibi yokuhlolwa kwegazi ye-anti-gluten antibodies. Ezinye iziguli ezingu-14 zenqaba ukulandela ukudla futhi ngakho-ke zasebenza njengeqembu lokulawula.
Ngaphambi kokuqala kokutadisha, abahlanganyeli babe nokusebenza okufanayo kokuhlolwa kwe-ataxia. Kodwa-ke, unyaka owodwa esifundweni, izimpawu zeqembu lezokwelapha ze-ataxia zithuthuke kakhulu uma kuqhathaniswa neqembu lokulawula. Ukuphuthuma kwezibonakaliso zezinzwa kwenzeka kungakhathaliseki ukuthi umuntu olandela ukudla okungenayo i-gluten wayene-atrophy eneqhwa futhi wayitholwe enesifo se-celiac noma cha.
"Ukuhlolwa kwe-neurophysiological ye-peripheral nerve function kwiziguli ezine-gluten ataxia kanye ne-peripheral neuropathy futhi kubonise ukuthuthukiswa, ukusekela ukuphikisana kwethu ukuthi ukuthuthukiswa eqenjini elihambisana nokudla okungenalo gluten kwakungokoqobo," kusho abacwaningi.
Futhi, ukuthuthukiswa kwenzeke kungakhathaliseki ukuthi iziguli zazihlupheke kangakanani kusukela ku-ataxia, kanti ezinye iziguli ezitholakale zamuva zilahlekelwe yizo zonke izimpawu ze-ataxia futhi zabuyela ekujwayelekile okulandela ukwelashwa ngokudla okungekho gluten, kusho abacwaningi.
Isifundo Sesibili Sihlulekile Ukuthola Umthelela Wezondlo
Esifundweni sesibili, eshicilelwe ngo-2011, iqembu labacwaningi abavela eMayo Clinic lalandela iziguli ezingu-57 ezine-atxia ezilindelekile ze-gluten kanye ne-peripheral neuropathy, ezinye zazo zazivivinya igazi eliphikisana ne-anti-gluten kanti ezinye zazo zinezici eziphikisayo zesifo se-celiac.
Cishe isigamu seziguli zamukelwa ukudla okungekho gluten, kanti enye ingxenye yayingenalo. Kulezi ziguli ezinokudla okungenayo i-gluten, izimpawu zesifo sezinzwa zathuthuka ngo-16%, zahlala zizinzile ngo-37%, futhi zanda kakhulu ku-47%. Eqenjini elingazange lilandele ukudla, i-9% ithuthukisiwe, i-18% yahlala isimeme futhi u-73% wehla kakhulu. Kodwa-ke, lezo zingxabano azifinyelelanga ngokubaluleka kwezibalo.
Abacwaningi babhala bathi: "Kubonakala sengathi izimpawu ze-neuropathic [okungukuthi, ukuxosha emaphethelweni] ezigulini ezingenayo i-chance zingase zithole ithuba elingcono lokuthola (uma likhona) ekudleni okungenayo i-gluten kunezimpawu ezinobuthi." "Asizange sibone ukuthuthukiswa kwe-ataxia ne-gluten-free diet noma iziguli eziphethwe yi-celiac noma ezingekho-celiacs."
Abacwaningi baphetha ngokuthi "ubufakazi obukholisayo bokuthi inzuzo ngokwemiphumela ye-neurologic namanje ayitholakali."
Kukhona futhi imibiko eminingi yamacala ebonisa ukuthi ukudla okungenayo i-gluten kungaxazulula izimpawu ezihlobene negazi kanye nezinye izimpawu zezinzwa kubantu abanesifo se-celiac, nakuba kuleyo mibiko, abacwaningi babenesithakazelo ngokuyinhloko ezimpawu zamathumbu futhi abazange bagxile ezimpawu ze-ataxia .
UDkt. Hadjivassiliou: Ukudla Okungenalutho Kwe-gluten Kumele Kube Mandla
Ukuze usebenze njengokwelapha i-gluten ataxia, ukudla okungekho gluten kufanele kube okuqinile: Awukwazi ukukopela ekudleni okungenalutho kwe-gluten nhlobo , futhi kungase kudingeke uqede imikhiqizo "engenayo i-gluten" enamanje encane inani lokulandelela i-gluten, ngokusho kukaDkt. Hadjivassiliou.
Lokhu kungase kube ukudla okunamandla kunokuba kudingekile ukuqeda umonakalo wamathumbu, "usho kanje. "Kubalulekile ... ukuthi ukuqapha okufuze kwenziwe ngokusetshenziswa kwama-antigliadin antibodies [okungukuthi, ukuhlola igazi kwe-celiac ] nokubuyekezwa kwe-dietetic ukuqinisekisa ukunamathela ngokuqinile ekudleni," kusho uDkt. Hadjivassiliou kanye nabalobi bezobambiswano.
Uma kungekho ukuthuthuka ngemva konyaka ekudleni okungenalutho kwe-gluten, isifundo sasikisela ukuthi ukwelashwa nge-immunosuppressants kanye neminye imithi kungafaneleka.
Imithombo:
Fasano A. et. al. I-spectect yezinkinga ezihlobene ne-gluten: ukuvumelanisa ngokuchazwa kwamagama okusha nokuhlukaniswa. BMC Medicine. 2012, 10:13 ini: 10.1186 / 1741-7015-10-13. Kushicilelwe: 7 Februwari 2012.
Hadjivassiliou M. et al. Ukwelashwa kokudla kwe-gluten ataxia . Journal of Neurology, Neurosurgery and Psychiatry. 2003 Sep; 74 (9): 1221-4.
Hadjivassiliou M. et al. I-Gluten Ataxia. I-Cerebellum. 2008; 7 (3): 494-8.
Rashtak S. et. al. I-Serology ye-celiac isifo se-ataxia esibhekene ne-gluten noma i-neuropathy: indima ye-antiamidated gliadin antibody. I-Journal ye-Neuroimmunology. 2011 Jan; 230 (1-2): 130-4. Epub 2010 Nov 6.