Kuvunywa ukuthi umuntu onabantu abangu-133 unesifo se-celiac , isimo sezakhi zofuzo esibangela ukulimala emathunjini noma ngabe kunini lapho edla i- gluten , amaprotheni athola ukolweni, ibhali kanye ne-rye.
Kodwa-ke, abacwaningi bamanje nje babone ukuzwela okungenayo i -celiac gluten njengendlela ehlukene, isimo esicacile, kanti abanye emkhakheni wezokwelapha balinde ukuqinisekiswa kwalezo zinsuku ezintsha zokwenza ucwaningo ngaphambi kokwamukela ukuzwela kwe-gluten njengendlela yokuxilongwa.
Kungenzeka futhi ukuthi akuyona i-gluten emva kwakho konke-kunalokho, kungase ibe enye into kakolweni nakwezinye izitshalo eziqukethe i-gluten ezibangela ezinye noma zonke izimpendulo kubantu "abano-gluten" -senhliziyweni.
Njengoba kunikezwe konke lokho, kanye nokuthi akukho ukuhlolwa okuvunyelwe kokwezwela kwe-gluten , akunakwenzeka ukusho ngokuqinisekile ukuthi bangaki abantu abangaba ne-gluten-sensitive. Abacwaningi balinganise ukuthi kungaphansi kuka-0.6% wabantu (noma abayisithupha kubo bonke abantu abangu-1 000) noma abaphakeme ngaphezu kuka-6% wabantu (ayisithupha kubo bonke abantu abangu-100), kodwa akukabikho uphenyo olucacile izinombolo.
Kodwa-ke, abacwaningi abathathu abavelele emkhakheni - uDkt. Alessio Fasano, uDkt. Kenneth Fine, noDkt. Rodney Ford - usanda kukhuluma nami futhi bacabanga ukuthi yiziphi amaphesenti. Vele uqaphele ngaphambi kokuthi ufunde ukuthi amaphesenti ashoyo asekelwe ekucwaningeni kwawo (ikakhulukazi angashicilelwa), futhi awabonakali umbono ozokwelapha wezokwelapha.
UDkt. Fasano: Ukuzwela kwe-Gluten Kungathinta u-6% kuya ku-7%
UDkt. Fasano, umqondisi we-University of Maryland Center for Celiac Research, washicilela isifundo sokuqala ebheka isisombululo se-gluten ukuzwela nokuthi ihluke kanjani nesifo se-celiac. Wabuye wabamba iqhaza kulolu cwaningo oluphetha ngokuthi lesi sifo sesifo se-celiac singesinye kubantu abangu-133.
Ngokusho kukaDkt. Fasano, ukuzwela kwe-gluten kungabathinta abantu abaningi kakhulu kunesifo se-celiac. Ulinganisela ukuthi cishe u-6% kuya ku-7% wabantu base-US bangase babe nokukhathazeka kwe-gluten, okusho ukuthi abantu abayizigidi ezingu-20 e-United States kuphela babe nesimo.
Izimpawu zokuzwela kwe-gluten kule ndawo zingabandakanya izinkinga zokugaya, ukukhanda ikhanda, ukukhwabanisa nezibonakaliso zesikhumba ezifana ne-eczema, ubuchopho bobuchopho nokukhathala, kusho uDkt. Fasano. Cishe ingxenye eyodwa kwezintathu kwalabo abatholwa ukuthi yi-gluten-sensitive sensitive report ubuchopho bubuchopho kanye nezinsizwa njengezimpawu, uthi.
Odokotela. I-Ford, i-Fine Say Percentage ingaba yiPhakeme kakhulu - ifike ku-50%
UDkt Ford, udokotela wezingane e-Christchurch, eNew Zealand kanye nomlobi weThe Gluten Syndrome , uthi ukholelwa ukuthi iphesenti labantu abanobucayi obukhulu kungaba ngcono kakhulu-okungenzeka kube phakathi kuka-30% no-50%.
"Kunabantu abaningi kakhulu abagulayo," usho kanje. "Okungenani u-10% u-gluten-sensitive, futhi cishe ufana no-30%. Ngangifaka intamo yami eminyakeni eminingi edlule lapho ngithi okungenani u-10% wabantu yi-gluten-sensible." Ozakwethu bezokwelapha bathi ukuzwela kwe-gluten akuzange ' siphila. Singase sithole ukuthi singaphezu kuka-50% uma sigcina sigxile kwinombolo. "
UDkt Fine, i-gastroenterologist eyasungula futhi iqondisa insizakalo yokuhlola ukuzwela kwe-gluten, i- Enterolab , iyavuma ukuthi ukuzwela kwe-gluten kungenzeka kuthinte ingxenye yesigamu.
UDkt Fine usolwa ukuthi u-10% kuya ku-15% wabo bonke abantu baseMelika banama-antibodies wegazi (noma i- AGA-IgA noma i- AGA-IgG antibodies) eya ku-gluten, okuzokhombisa ukuthi amasosha omzimba ayasabela kumaprotheni.
Omunye amaphesenti amakhulu aseMelika anezinkinga ezizimele, isifo sofuba esingamangalisa , isifo esibuhlungu esibuhlungu kanye / noma ubuchopho obukhulu, obubeka engozini enkulu yokuzwela kwe-gluten. Abantu abangaba ngu-60% kuya ku-65% abanemibuzo yokuhlolwa kwe-gluten nge-Enterolab, uDkt Fine uthi.
Okwamanje, abangaba ngu-20% kuya ku-25% wabantu abangenazo izimpawu kuthiwa benokuzwela kwe-gluten okusekelwe emiphumeleni yokuhlola yakwa-Enterolab, uDkt Fine uthi.
"Lapho senza lezi zibalo, sakhula nenani elilodwa cishe kokubili yi-gluten-sensitive," usho kanje.
Phakathi naleso sikhathi, uDkt Fine uthi ukholelwa ukuthi inani elilinganiselwa ku-133 labantu abanesifo se-celiac singase sibe phezulu kakhulu - "Ngicabanga ukuthi kufana nesinye esingu-200. Ngikwazi ngokugcwele okufundwayo kwaba ngu-133 kodwa okwamenywe nokukhethwa okuncane. " Ezinye izifundo ziye zafaka izifo zesifo se-celiac cishe kubantu abangama-200 kubantu abayi-250, kanti uDkt Fine uthi ucabanga ukuthi lezo zinembile kakhulu.
Yenzani Le Nomboro Yokuzwela KweGluten?
Njengamanje, la maphesenti angabonakala abantu abangase abe nokuzwela kwe-gluten abhekisela ekucatshangeni okuyingxenye yalaba odokotela nabacwaningi - lezi zifundo azikwenziwanga nje ukufakazela ukuthi zinembile yini noma zifinyeleleke kakhulu.
Imithombo:
I-Czaja-Bulsa G. Ukungahloniphi kwe-Celiac Gluten - Isifo Esisha Esine-Gluten Inxerance. Ukudla okunomtholampilo (e-Edinburgh, eScotland). 2015 Ngo-Apr; 34 (2): 189-94.
UFasano A. et al. Ukuzivocavoca kwe-Gut Permeability kanye ne-Mucosal Gene Immune Expression in Two Gluten-Associated Conditions: Izifo Ezibucayi Ne-Gluten Ukuzwela. BMC Medicine 2011, 9:23. i-doi: 10.1186 / 1741-7015-9-23.
Fasano A. et. al. Isibuko sezinkinga ezihlobene noGluten: Ukuvumelana ngokuSishayamagama Esisha nokuHlelwa. BMC Medicine. BMC Medicine 2012, 10:13 ini: 10.1186 / 1741-7015-10-13. Kushicilelwe: 7 Februwari 2012