Ukuhlolwa kusetshenziselwa ukuxilonga isifo se-celiac kanye nokuzwela kwe-gluten
Ukuhlolwa kwegazi kwe-AGA-IgG ingenye yephaneli lezinhlanu zokuhlolwa kwegazi le-celiac ezisetshenziselwa ukuhlola nokuhlola isifo se-celiac . Ibuye isetshenziselwe ukusiza ukubona ukuzwela okungenayo i -celiac gluten , nakuba ucwaningo lwezokwelapha lubonisa ukuthi akuyona into enembile ngaleyo njongo.
I-AGA imelela ama-antigliadin antibodies, okuyi-antibodies eqondile akhiqizwa ngumzimba ngokuphendula nokuxhumana ne-gliadin, ingxenye ye- molecule ye- gluten .
I-IgG imele i-immunoglobulin G, engama-molecule-anti-antibody.
Isivivinyo segazi se-AGA-IgG esihle sibonisa ukuthi umzimba ungase uphakamise ukusabela kwesimiso somzimba wamagciwane ekungeneni kwe-gluten, kodwa kubhekwe njengokuncane kakhulu kunezinye izivivinyo zegazi. Kodwa-ke, ukuhlola okuhle kwe-AGA-IgG kungabonisa isifo se-celiac esigulini esinokukhubazeka kwe-IgA , okuyinkinga ngesimiso sakho somzimba sokuzivikela omzimba esikushiya ukwedlula ukutheleleka.
Ukusetshenziswa
Njengoba i-AGA-IgG yokuhlolwa kwegazi ingabonisa ukuthi umzimba wakho uphendukela ku-gluten (ngisho noma lokho kungasetshenzisiwe okutholakala esihlokweni se-celiac), abanye odokotela basebenzisa lolu luhlolo njengethuluzi lokubasiza ukuba bahlolisise ukuzwela kwe-gluten okungenayo i-celiac.
Noma kunjalo, ucwaningo lwezokwelapha alubonanga ukuhlolwa ukusebenza konke lokho. Esifundweni sika-2015 eshicilelwe ku- Clinica Chimica Acta (I-International Journal of Clinical Chemistry) , odokotela baqhathanisa imiphumela yokuhlolwa kwegazi kubantu abanezinsolo zokungaboni kahle kwe-gluten ezingenaso celiac nemiphumela evela kubantu abanesifo se-celiac nabantu abangenaso isimo.
Ngemva kokuhlola idatha, baphetha ngokuthi i-AGA-IgG ukuhlolwa kwegazi akuyona ukuhlolwa okubucayi kakhulu kokungaboni kahle kwe-gluten, okusho ukuthi ilahlekelwa abantu abathile abanesimo ngempela. Imiphumela yokuhlola ye-AGA-IgG ingasiza ekuxilongweni, abacwaningi bathi, kodwa kuphela uma imiphumela ihlanganiswa nezinye izici.
Iyiphi enye i-AGA-IgG esetshenziselwa yona?
Izinga eliphezulu le-AGA-IgG litholakale kwezinye izingane ezixilongwa nge-autism. Kwesinye isifundo, izingane ze-autistic ezazinamazinyo emathunjini zinamazinga aphezulu e-AGA-IgG kunabantwana be-autistic ngaphandle kwezinkinga zokugaya ukudla.
Isivivinyo se-AGA-IgG singasetshenziselwa ukusiza ukuxilonga i- ataxia ye-gluten , isimo somzimba esizimele lapho umzimba wakho uphendukela ekungeneni kwe-gluten ngokuhlasela ingxenye yengqondo yakho. I-gluten ataxia ingabangela ukulahlekelwa kokuhlanganiswa okuthinta umthamo wakho, ibhalansi yakho, ngisho namahlo akho.
Umbiko wokuvumelana ovela kubaphenyi abaphezulu emkhakheni wezifo ze-celiac kanye nokungazweli kwe-gluten okungewona i-celiac uncoma odokotela ukuba bahlole ukuhlolwa kwegazi kwe-AGA-IgG ngekhonsathi nezinye izivivinyo zegazi uma bebheka ukuthi i-gluten ataxia.
> Umthombo:
> Infantino M. et al. Ukuchithwa kwesifo se-anti-gliadin antibodies kuziguli ezingezona i-celiac gluten senitivity (NCGS): Indlela ephindwe kabili yezibalo. Clinica Chimica Acta (I-International Journal of Clinical Chemistry). 2015 Sep 22. pii: S0009-8981 (15) 00426-X.
> Isikhungo Sezifo Ezigulayo eCeliac e-Columbia University. I-Serologic ne-Genetic Testing (i-fact sheet).
> University of Maryland Center for Celiac Research. Izifo ze-Celiac Imibuzo Ebuzwa Ngokujwayelekile (i-fact sheet).