I-Doxepin ingasiza ama-hive nokushaya, kodwa imithi nayo inezimo ezimbi eziqinile futhi kudingeka isetshenziswe ngokuqapha. I-Doxepin iyi-drug tricyclic ephikisana nokucindezeleka eyenza i- antihistamine enamandla, eyenza ibe yusizo ekwelapheni ama- hive angapheli nokuluma . I-Histamine ikhiqizwa ngamasosha omzimba wakho njengesivikelo sokuqala ngokumelene nezilonda.
Uma une-allergies, umzimba wakho ungaveza i-histamine kakhulu noma ungadala i-histamine ekuphenduleni i-allergen engenangozi, njenge-pollen. I-Doxepin iyakwazi ukuvimbela i-H1 ne-H2, izinhlobo ezimbili ze-histamine receptors, okwenza ukuthi iphumelele ngokukhethekile ekuphatheni izifo zesikhumba , ngoba kokubili i-H1 ne-H2 histamine receptors ingatholakala esikhumbeni.
I-Doalepin yama-Oral ne-Topical
I-Doxepin itholakale kuphela ngodokotela, kanti umthamo uhlukahluka ngokusekelwe ezimpawu zokuphathwa. Ngemihlathi kanye nokushaya, odokotela abaningi basebenzisa amanani aphansi, njengama-milligram angu-25 kuya kwangu-50 ngaphambi kokulala. Amanani aphezulu e-Doxepin asetshenziselwa ukuphatha ukucindezeleka nokukhathazeka, nakuba kunzima kubantu abaningi ukubekezelela ukulinganisa okuphezulu kwale mithi ngenxa yemiphumela yaso emibi ye-sedation nokulala.
I-Doxepin ingasetshenziselwa ukukhulula izimpawu ze-eczema. Uma umisiwe i-Doxepin ye-eczema, uzonikezwa ukhilimu ongokwesibhakabhaka ongawusebenzisa.
Ezimweni eziningi, ukhilimu usetshenziswe izikhathi ezine ngosuku ngezinsuku eziyisishiyagalombili. Imiphumela emibi ye-Doxepin yezobuciko ihlanganisa ukulala, umlomo owomile, ukuwohloka kwamanzi, ukukhwabanisa, ukukhathala, isizungu, ukushintsha kwemizwelo, ukuvutha nokugxila kwisayithi lesicelo, ukukhula okunamandla, ukomisa nokuqinisa kwisayithi lesicelo, ukugoqa eminwe nasezinzwaneni, nokuvuvukala .
Okufanele Ukwazi Ngaphambi Kokuthatha i-Doxepin
I-Doxepin ithatha isixwayiso sebhokisi elimnyama ngoba lingandisa ingozi yokuzibulala ezinganeni nakubantu abadala asebephethe umlando wokucindezeleka noma ukugula kwengqondo. I-Doxepin inokuxhumana okuningi kwezidakamizwa neminye imithi, ngakho-ke kubalulekile kunoma yimuphi umuntu othatha i-doxepin ukukwazisa udokotela noma umuthi mayelana neminye imithi abayithathayo. Ngenxa yemiphumela emibi eminingi , imiyalelo ye-doxepin ivame ukuqala iphinde ikhule kancane.
Uma uthatha i-Doxepin futhi unqume ukuyeka, kuzodingeka uzisuse kumuthi ukuze ugweme izimpawu zokuhoxisa njenge-nausea, ukuhlanza, isifo sohudo, isisu, izinkinga zokulala, isizungu, ukukhathala nokucasula. Ungayeki ukuthatha i-Doxepin ngokuzumayo noma ngaphandle kokubonisana nodokotela wakho.
Nakuba i-doxepin ingaba usizo kakhulu ekwelapheni imifantu nokuluma, kufanele ithathwe ngokucophelela nangaphansi kokuqapha ngokucophelela udokotela.
> Imithombo:
> Fleischer AB. I-Histamine H1 Antagonists. N Engl J Med. 1994; 331: 1019-1020.
> DuBuske LM. Ukuqhathaniswa Kwemitholampilo Yomlando H1-Receptor Antagonist Izidakamizwa. J Allergy Clin Immunol. 1996; 98: S307-18.
> I-US National Library of Medicine: I-Medline Plus. I-Doxepin Topical. 2016.