I-hormone ye-antidiuretic, noma i-ADH, i-hormone eveza i-hypothalamus futhi ikhishwe yi-gland pituitary. Umsebenzi oyinhloko ukugcina ingcindezi yegazi, ivolumu yegazi namanzi amathishu.
Abesifazane abane- polycystic ovarian syndrome , noma i-PCOS, basengozini yokucindezeleka kwegazi futhi bangase babe nokungalingani kwe-ADH.
Eyaziwa nangokuthi i-vasopressin, i-ADH ikhuthaza ukuchotshozwa kwemisipha ebushelelezi futhi ibangela umzimba ukuba ugcine amanzi, usiza ekuvimbeleni ukuphelelwa amandla kwamanzi.
I-ADH ishicilelwe lapho amaseli akhethekile ebuchosheni noma enhliziyweni ebona ushintsho ekuhlungeni kwegazi noma kwegazi.
Uma ikhishwe, i-ADH ihambela izinso lapho ibonisa amangqamuzana athile ukuthi aphinde avuse amanzi emcinini agcinwe ezintsheni, avimbele amanzi ukuba alahleke ngokuchama. Lokhu kwandisa kokubili ivolumu yegazi nomfutho wegazi.
Izinga le-ADH elishintshileyo
Amazinga aphezulu e-ADH angabangela ukugcinwa kwamanzi. Isimo esaziwa ngokuthi i-Syndrome ye-Inappropriate Anti-Diuretic Hormone secretion (SIADH) ikhiqiza i-ADH eyengeziwe ukuze ikhishwe uma ingadingeki.
Amazinga aphakeme kakhulu e-ADH angase abe nomphumela ohlangothini wemithi ethile, noma obangelwa isifo noma isisu emaphashini, hypothalamus noma gland pituitary.
Ngakolunye uhlangothi, ukuphuza utshwala kuvimbela ukukhululwa kwe-ADH, okwenza ukwanda komchamo wokukhiqiza umchamo nokuphelelwa amandla kwamanzi.
Izimpawu zokungalingani kwe-ADH zihlanganisa ukucwenga, ukuhlanza, ukuhlukunyezwa kwemisipha, ukudideka nokuxuba.
Ukuhlolwa kwe-ADH
Udokotela wakho angalawula ukuhlolwa kwe-ADH uma uzwa ukoma ngokweqile, ukuvuthwa okuvamile noma ukuphelelwa amandla kwamanzi , noma ube namazinga ajwayelekile egazi le-sodium. Uhlolo lingabuye lwabizwa nge-AVP noma i-arginine vasopressin.
Ukuthola isilinganiso esilungile se-ADH, noma kunjalo, kungaba yinkimbinkimbi, ngoba i-molecule encane kakhulu enomzuzu omfushane.
Ngezinye izikhathi odokotela basebenzisa i-copeptin njengesivumelwano se-ADH. I-Copeptin iye yaxhunyaniswa ne- atherosclerosis kanye nesifo senhliziyo, futhi ingasetshenziswa ukukhomba ukuhlaselwa kwenhliziyo ekuqaleni.
I-ADH ne-Heart Heart
Ucwaningo lwamuva olushicilelwe kuyi- Journal of Ovarian Research lwathola amazinga aphezulu e-copeptin adlala indima ebalulekile ekuphenduleni komzimba kanye nokuthuthukiswa kwesifo sokuqina kwesifo somzimba ku- insulin ukumelana , abesifazane abano-hyperandrogenemic ne-PCOS.
Olunye ucwaningo oluthola, kulaba besifazane abane-PCOS, amazinga we-copeptin aphezulu kuneziguli ezikhulu kakhulu kunezilinganiso ezijwayelekile, futhi uncoma ukuhlolwa kwe-copeptin ukuhlola ingozi ye-cardiovascular in patients PCOS.
Imithombo:
Karbek B, Ozbek M, Karakose M, et al. I-Copeptin, umaka wokuzikhethela we-arginine vasopressin, ukhonjiswe ngengozi yengqondo kumagulane ane-polycystic ovary syndrome. J Ovarian Res . 2014 Mar 14; 7:31. i-doi: 10.1186 / 1757-2215-7-31.
I-Taskin MI, i-Bulbul E, i-Adali E, i-Hismiogullari AA, i-Inceboz U. Amazinga ajikelezayo obestatin futhi aphethwe ngabesifazane abakhulu kakhulu nabangenabo abane-polycystic ovary syndrome. I-Eur J Obstet Gynecol I-Biol ephikisayo . 2015 Jun; 189: 19-23. i-doi: 10.1016 / j.ejogrb.2015.03.006.