Izinhlobo, Ukwelashwa Nokuguqulwa
Umdlavuza we-ovariya uyenzeka kwabasikati abasebasha, kodwa kunezindlela eziningana ezihlukile kwabesifazane abadala.
Abesifazane Abancane nabesifazane Abadala
Nakuba umdlavuza we-ovary epithelial ungenakwenzeka kubantu besifazane abaneminyaka engaphansi kwengu-40 ubudala, kungenzeka futhi kwenzeke kwabesifazane abasebasha. Uma kutholakala kuma-40s wesifazane, noma ngaphambi kokuthi afinyelele kubo, kuvame ukuhlobene nezici zefa kanye ne-BRCA1 noma i-BRCA2 (izakhi ezithinta kakhulu ingozi yombili umdlavuza we-ovarian nesifuba).
Ngisho nasekuqaleni kweminyaka, ikakhulukazi uma kunomlando womndeni walezi zomshukela, ukunakekelwa kwezimpawu eziqhubekayo zesisu nangokomzimba kubalulekile.
Izinhlobo Ezivamile Ze-Ovarian Cancer Kwabesifazane Abasha
Umdlavuza we-Ovarian empeleni kunezifo eziningi zezifo, futhi kunezinhlobo ezingaphezu kwezingama-30 ezaziwayo. Uhlobo ngalunye lukwazi ukuziphatha ngendlela ehlukile futhi luphendule ngokuhlukile kumalungiselelo wokwelashwa. Kunezigaba ezimbili eziyinhloko zomdlavuza we-ovarie ezenzeka ngokuyinhloko kwabesifazane abasebasha: i-germ cell kanye nezicubu ezincibilikisa ucansi. Nansi ukubuka okufingqiwe kwalowo nalowo:
Germ Cell Cell Izidumbu
Lezi zomshukela zivela emangqamuzaneni e-ovary okuhloswe ukuba abe amaqanda futhi awavamile, amele amaphesenti angu-5 kuphela e-cancer. Cishe amaphesenti angu-70 alawo mathambo atholakala ekuqaleni, kepha avame ukuba nezicubu ezikhula ngokushesha. Lezi zicubu zivame ukutholakala kwabesifazane abasekuqaleni kwawo-20. Ama- sub-izinhlobo eziyinhloko kulesi sigaba zifaka:
- i-dysgerminomas
- izidumbu ze-endodermal sinus
- ama-teratomas amancane
Amakhamera we-tumor -Lezi zomshukela zivame ukhiqiza izimpawu ze-tumor-LDH, AFP ne-hCG-ezilinganiselwe egazini. Lezi yizincazelo eziyinhloko ezingasiza ochwepheshe ukuba banqume, ngisho nangaphambi kokuhlinzwa, lokho okungahle kwenzeke khona. Uma ubona i-hCG, kungenxa yokuthi i-hormone evivinywa ukuhlolwa kokukhulelwa.
Njengoba lezi zicubu zingase zifihle leli hrimoni, futhi njengoba esinye sezibonakaliso zomdlavuza we-ovari yisiswini sokubeletha esiswini, lezi zilambu ziqala ngezinye izikhathi zingaboni kahle ukuthi zikhulelwe.
Ukwelapha - Ukwelashwa kuyadingeka ukuze kunqunywe i-subtype ngqo futhi ubone ukuthi umdlavuza usakaze yini. Abesifazane abaningi bakhathazekile ngokuthi ukukhetha ukwelashwa njengendlela yokwelashwa kuyoba nomthelela ekuzaleni kwabo. Nokho, ezimweni eziningi, i-ovary eyodwa kuphela kumele isuswe, ngakho-ke ukuzala ngokuvamile-kungenjalo ngaso sonke isikhathi-kungakwazi ukusindiswa. Kulesi simo, enye i-ovary, tube fallopian, kanye nesibindi ishiyiwe endaweni, futhi ukukhulelwa kungase kwenzeke ngokuvamile. Bavame ukuzwela kakhulu ekhemotherapy futhi ngenxa yalokho bavame ukuphulukiswa, ikakhulukazi uma bethola ezinkathini zokuqala. Ukwelashwa kwe-teratoma engakafiki kuyinkimbinkimbi kunezinye izifo ze-germ cell.
I-Sex Cord I-Stromal Tumors
Lezi zomshukela ziqala emangqamuzaneni amathishu ahlangene abamba ama-ovari ndawonye bese enza ama-hormone afana ne-estrogen, progesterone, ne-testosterone. Zimelela ngamaphesenti angu-6 azo zonke izinhlobo zomdlavuza we-ovarian futhi ikakhulukazi zenzeka kwabesifazane abasebasha. Ngokuvamile, bavame ukukhula kancane kancane. I-subtypes eyinhloko yilezi:
- iseli le-granulosa stromal
- izicubu ze-sertoli-Leydig
Ama-tumor we-Granulosa ase-stromal cells angase akhiqize i-hormone ebizwa ngokuthi i- inhibin, engasetshenziswa njenge-marker marker. Ukutholakala kwezifo ngokuvamile kwenziwa esiteji sokuqala sesifo, futhi ifomu elithi "omdala" (ngokuvamile elitholakala ezigulini ezineminyaka engaphezu kwengu-40) ngokuvamile alinamandla kakhulu. Kodwa-ke, ifomu okuthiwa "i-juvenile" (okuningi kodwa hhayi wonke amacala aphakama eminyakeni yokuqala yokuphila engu-20) ivame ukutholakala ezinyathelweni eziphambili. Ngeshwa, ayiphenduli kakhulu kumakhemikhali.
Ama-tumorous (serousine) ama-Sertoli ne-Sertoli-Leydig cell tumors awavamile. Iningi liyisifo sengculaza esinamandla noma esingenamandla. Iningi litholakala ezinkathini zokuqala futhi linyango kakhulu ngokuhlinzwa kuphela.
Njengoba zikhiqiza i-estrogen noma i-testosterone, izimpawu zokuqala ngokuvamile zinokuthile okuphathelene nokushintsha kwama-hormonal. Lezi zimpawu zingabandakanya ukukhula kwezinwele ebusweni, izwi eliphansi, nokukhulelwa kanye / noma izikhathi ezingavamile.
I-Genetics ne-Hereditary I-Ovarian Cancer
Njengoba kuphawuliwe ngenhla, izakhi zofuzo zidlala indima ebalulekile kwabesifazane abathile abahlakulela umdlavuza we-ovarian esemncane. Khuluma nodokotela wakho. Funda ngesifo somdlavuza we-breast and ovarian . Ukuhlolwa kwe-Genetic manje kuyatholakala.
I-Ovarian Cancer nokuzala
Njengoba kuphawuliwe ngenhla, ukuhlinzeka kungavumela ukuthi amanye ama-ovari ashiywe endaweni. Kubalulekile ukuphawula ukuthi ngisho nangokwesifo esibelethwayo, i-chemotherapy ngezinye izikhathi ingabangela ukuhluleka kwe-ovarian, okuhlala njalo. Ngaphambi kokwelashwa qiniseka ukuthi uthatha isikhathi sokukhuluma nodokotela wakho mayelana nokulondoloza ukuzala kwakho ngaphambi kokwelashwa komdlavuza .
Izwi elivela
I-Cancer isifo esesabekayo, ngisho noma unesinye salezi zicubu, okungathi uma uthathwa kusheshe kuphulukiswa kakhulu. Buza imibuzo eminingi. Funda ukuthi ucwaninga kanjani umdlavuza wakho ku-intanethi . Finyelela emndenini nabangani ukusekela. Kunomphakathi oqinile wabasindile omdlavuza ovarian omdala abasebenza kakhulu emphakathini wezokuxhumana. Abaningi ngisho banamabhulogi lapho bahlanganyela khona ngohambo lwabo lomdlavuza, njengoFran Dresher's Cancer Schmancer. Ngokufanayo, kuneqembu elikhuthele labantu abasha abaye basinda ezincelweni zomdlavuza wazo zonke izinhlobo ezibizwa ngokuthi i-Stupid Cancer: Izwi leCancer Young Young.
Akufanelekile ukuba ubhekane nomdlavuza lapho usencane-noma kunanoma yisiphi isikhathi. Siyabonga ukuthi sifunda kabanzi mayelana nokusinda kanye nezindlela zokusiza abesifazane (namadoda) baqhubeke njalo nangemva kokulashwa komdlavuza. Futhi, uma unezinsuku lapho uzizwa ungalungile, khumbula ukuthi izifundo manje zisitshela lokho esikucabangayo ngaphambili. I-Cancer ishintsha abantu ngezindlela ezinhle , hhayi nje embi!
> Imithombo:
> Isaacs C, Peshkin B. Ukuphathwa kweziguli ezinomdlavuza webele kanye / noma womndeni kanye nomdlavuza we-ovari. Kusesikhathini. Kubuyekezwe 07/05/15.
> National Cancer Institute. I-BRCA1 ne-BRCA2: Ingozi yeCanscer and Testing Genetics. Kubuyekezwe 04/15/15.
> National Cancer Institute. I-Ovarian Germ Cell Tumors Treatment (PDQ). 0212/16.
> Ray-Coquard Mina, Brown J, Harter P, et al. I-Gynecologic Cancer InterGroup (GCIG) ukubuyekezwa kokuvumelanisa kwama-tumor we-ovarian sex cord stromal tumors. I-International Journal ye-Cancer Gynecologic . 2014. 24 (9 Isithathu 3): S42-7.
> Simone C, Markham M, Dizon D. Chemotherapy emathunjini omzimba wegciwane lesandulela ngculazi: Ukubuyekezwa okuhlelekile. I-Gynecologic Oncology . 2016. (i-Epub ngaphambi kokuphrinta).