Ngezinye izikhathi i-Plasmapheresis isetshenziselwa ukwelashwa kwezifo eziningana ze-neurological kuhlanganise ne-MS, ikakhulukazi ngesikhathi sokubuyela emuva okunamandla okungaphenduli i- corticosteroids . Kuyinkambinkimbi enhle, futhi imiphumela emibi ayifani.
Kuyini i-Plasmapheresis?
I-Plasmapheresis, eyaziwa nangokuthi ukuguqulwa kwe-plasma, iyinkqubo lapho umshini ngaphandle komzimba womuntu ususa igazi kumuntu bese uhlukanisa ingxenye ye-plasma yegazi - i-plasma ibe ingxenye yegazi noma ingxenye egazini yegazi.
Khona-ke i-plasma ilahlwa futhi ishintshwe ngohlobo oluthile lwamanzi aphuzi, ngokuvamile i-donor plasma noma i-albin solution, ngaphambi kokubuyiselwa kumuntu.
Iyini Injongo YePlasmapheresis?
Umgomo we-plasmapheresis ukukhipha izinto ezilimazayo noma "ezimbi" egazini. Esimweni se-MS, lezi zingasetshenziswa izici zesimiso sokuzivikela ezihlasela isimiso sezinzwa zomphakathi.
Inqubo
Phakathi ne-plasmapheresis, izinaliti zizofakwa ezandleni zombili zombili, noma ngezinye izikhathi zibe kwenye indawo, njengentamo, uma imifino engalweni ingatholakali. Igazi lizoxoshwa emzimbeni wakho ngokusebenzisa inaliti esandleni esisodwa. I- anticoagulant (ngokuvamile i-citrate) ingeziwe egazini ukuyivimbela ukuthi ingagudli. Igazi lakho lizobe lihamba phakathi kwebhulethi libe "isahluli segazi segazi." I-cell separatorator yi-centrifuge ehlukanisa i-plasma kusuka kwezinye izingxenye zegazi lakho, okuyizingxenye zamaselula (ezihlanganisa amangqamuzana egazi abomvu, amaseli egazi amhlophe, namaplatelet).
Izingxenye zamaselula zihlanganiswa ne-plasma yomnikeli esikhundleni futhi babuyele kuwe ngenaliti kwenye ingalo. Kwezinye izimo, lokhu kwenziwa ngeyodwa inaliti futhi ukuhlukaniswa nokuhlaziya kwenziwa ngama-batches amancane.
Uzizwa Kanjani?
Zonke izinyathelo okukhulunywe ngazo ngenhla zenzeka ngokuzenzakalelayo nangokuqhubekayo.
Okuhlangenwe nakho kwesiguli kufana nokuba nezinaliti ezimbili / izinhlanzi ezinezinhlobo ze-IV ezikhona futhi ubukele igazi liphuma ngapha nangapha, ngomshini, futhi emuva ngaphesheya. Inqubo yonke ithatha amahora amabili no-4 ukuqedela.
Abantu bangase bazizwe benesisindo esincane noma esihlosile kusuka enkambisweni. Futhi, abanye abantu babika ukuthi i-anticoagulant yengezwe egazini noma eminye yamanzi okufaka esikhundleni esetshenziswayo imbangela yokufaka izikhonkwane noma izikhonkwane-nezinaliti izinzwa eminwe nasezinzwaneni. Kukhona futhi kungaba ukunambitheka okumuncu emlonyeni. Kungase kube nesicasuli esincane nokukhathala.
Izingozi
Imiphumela emibi emibi evela e-plasmapheresis ayivamile. Into ephawuleka kakhulu yalezi yi-anaphylaxis, okuyisifo esiyingozi kakhulu esibhekene ne-plasma replacement fluid. Lesi esinye sezizathu zokuthi ukushintshaniswa kwe-plasma kwenziwa ngaphakathi kokuhlelwa kokuqapha.
Izifo ezivela e-plasmapheresis azivamile, ikakhulukazi zisebenzisa ubuchwepheshe obusha kanye nokushintsha kwamanzi kagesi. Kodwa-ke, abantu bangase bathambekele ekubambeni okuthile ngemva kwe-plasmapheresis, njengoba amasosha omzimba amaningi asuswa, futhi umuntu angase abe nomzimba omncane ongazivikeli kahle.
Okunye eminye imiphumela emibi ingabandakanya:
- Ukusabela okuncane okubangelwa yi-allergic, okuzizwa sengathi i-chills, i-fever noma i-rash kancane
- Ukuphuma ngokweqile
- Ihluli
- Isingeniso senhliziyo engavamile
- Yehlisa ukucindezeleka kwegazi
- Ukuphelelwa umoya
- Ukugquma noma ukuvuvukala
Ngaphansi
I-Plasmapheresis ngokuvamile inqubo ephephile nebekezelwe kahle. Lokhu kuthiwa, akusetshenzisiwe kaningi e-MS - nje lapho ukuphindaphindiwe kwe-MS okunamuntu kunzima futhi akuphenduli ohlelweni lomuthi lwe-steroid ejwayelekile. I-Plasmapheresis ayisetshenziselwa ukuphatha i-MS eyinhloko noma eyesibili eqhubekayo.
Imithombo
Cortese I et al. Ukubuyekezwa okusekelwe ebukhosini: I-Plasmapheresis enkingeni ye-neurologic: Umbiko we-Therapeutics and Technology Assessment I-Subcommittee ye-American Academy of Neurology. I-Neurology . 2011 Jan 18; 76 (3): 294-300.
I-Fridey JL, i-Kaplan AA. "I-prescription kanye namasu okuguqula i-plasma yokwelapha." Kusesikhathini. Kubuyekezwe Mashi 31, 2010.