Ingabe Ukuphuza Kwesifo Sakho Isibeletho Kungabangela I-IBS Yakho?
Ingabe imithi yakho yokuphuza inhliziyo ingaba negalelo kumpawu zakho ze- IBS ? Abacwaningi babheka ubuhlobo obukhona phakathi kokusetshenziswa kweproton pump inhibitors (i-PPIs) nokukhuphuka kwamagciwane amancane emathumbu (SIBO). Njengoba i- SIBO icatshangwa ukuthi iyimbangela yamanye amacala we-IBS , noma yikuphi ubuhlobo phakathi kwabathathu kubalulekile ukubheka.
Yini i-PPIs?
I-PPIs yimithi esebenza ngokucindezela ukuvimba kwesisu esiswini.
Ziyalelwe ukwelashwa kwezimo ezihlukahlukene zezempilo, kuhlanganise nesifo se-reflux se-gastroesophageal (GERD) nezilonda zamapulpus. Nakuba ama-PPI amaningi adinga ukugonywa kwemithi, kunezinye ezingaphezu kwe-counter. Okulandelayo yizibonelo ze-PPIs:
- Aciphex
- I-Dexilent
- Kapidex
- I-Nexium
- I-Prevacid
- Prilosec
- I-Protonix
- Zegerid
Nakuba ama-PPI ngokuvamile abhekwa njengophephile, asebenzisa ingozi encane ye-pneumonia, kanye nengozi yokutheleleka kwe- C difficile .
Kuyini i-SIBO?
I-SIBO yisimo lapho kunesilinganiso esiningi ngokweqile amabhaktheriya ngaphakathi emathunjini amancane . Lawa ma-bacteria enza ama-carbohydrates odlayo, okuholela ekuvutsheni nokuvuvukala ngaphakathi kwamathumbu. Izimpawu ze-SIBO zifaka:
- Ubuhlungu besisu
- Ukuvimbela
- Uhudo
- Ukuhlukana
- Flatulence
Isixhumanisi phakathi kwe-IBS ne-SIBO sisalokhu siphikisana kakhulu. Lokhu kubangelwa ngenye indlela, kubunzima ngokuhlolwa okuqondile kwe-SIBO.
Ukuxilongwa okucacile kungenziwa ngokuthatha isiko lesisindo esiqondile, noma kunjalo, ngokujwayelekile, iziguli zitholakale zitholakala ngokuhlolwa kokuphefumula kwe-hydrogen , isivivinyo esingaphansi, kodwa esingaqiniseki kangako. Nakuba ezinye zilinganisela ububanzi obuphezulu kakhulu ngokuhambisana phakathi kwe-IBS ne-SIBO, kungenzeka ukuthi i-SIBO idlala indima yegciwane lesiguli se-IBS kuphela.
Enye inkinga ukuthi akuwona wonke umuntu ovumelana neSIBO ukuthi yisifo. Abantu abaningi bangaba nobufakazi be-SIBO ngaphandle kwempawu. Ngakho-ke i-SIBO ingakaqondakali kahle futhi iningi elingashiwo ngakho ukuthi kuyisikhathi esisetshenziselwa ukuhlonza izimpawu zomuntu.
Ucwaningo mayelana nokuxhumana okungenzeka phakathi kwe-PPI Ukusetshenziswa kanye ne-SIBO
Imfundiso yokuthi i-PPI isebenza ekwenzeni ukuthuthukiswa kwe-SIBO isekelwe ekubeni isisu esiswini yisinye sezici ezivikela ukukhuphuka kwamabhaktheriya emathunjini amancane. Ngakho-ke, ukwehla kwesisu esiswini esivela ekusebenziseni kwe-PPI, ngenkathi kukhonza ukuphatha ukugula kwenhliziyo kanye nezilonda, kungase kubangele izinkinga ngaphansi kwenqubo yokugaya .
Ngempela, ucwaningo luye lwathola ukuthi ukwehla kwesisu esiswini kungakhuphula inani lamabhaktheriya emathunjini amancane. Yini engacacile, kungakhathaliseki ukuthi ukwanda lokhu kuholela ekuthuthukiseni i-SIBO nezimpawu zayo.
Kwesinye isifundo, cishe isigamu seziguli ezithatha i-PPIs isikhathi eside zivivinyelwe i-SIBO. Izimpawu zabo zavama ukwanda ngokweqile ngokuhamba kwesikhathi, kanti izimpawu ziqala ngokulula ezinyangeni eziyisithupha zokuqala, kodwa zanda ukuba zilinganise futhi zikhukhumale ngokuhamba kwesikhathi.
Ukuvimbela kanye nokuhuda kwakuyizimpawu eziyinhloko ezibikezelwe, kanti amaphesenti amancane weziguli abika ukuqothulwa nobuhlungu besisu.
Esicwaningweni esincane, abantu ababengenayo i-GERD engeyona i-GERD (NERD) futhi abangazange babike noma yiziphi izimpawu zamathumbu banikwe i-PPI izinyanga eziyisithupha. Ngemuva kwamasonto ayisishiyagalolunye yokwelapha, cishe isigamu seziguli sikhalaza ngokuqhaqhazela, kuyilapho izinombolo ezincane zikhononda nge-flatulence, ubuhlungu besisu, nesifo sohudo. Ngemuva kwezinyanga eziyisithupha ukwelashwa, cishe ingxenye eyodwa yesine yeziguli zahlolwa kahle nge-SIBO ngokuhlolwa kokuphefumula, futhi cishe ingxenye eyodwa yesihlanu yeziguli zahlangabezana ne-IBS yokuxilongwa .
Ukuhlaziywa kwe-meta kule ndaba kutholakala ukuthi kwakukhona ubufakazi bexhumanisi le-PPI / SIBO ezifundweni ezazisetshenziswa amasiko ezinyamazane ukuze zihlolwe i-SIBO, kodwa hhayi kulabo abasebenzisa ukuhlola umoya. Ngokusobala, ucwaningo olwengeziwe luyadingeka, ngokunye ukukhula okuhambisana nokuthi i-SIBO itholakale kanjani.
Okubalulekile
Kuze kube yi-SIBO eqondwa kangcono, noma ukuhlolwa okucacile okuhlolisisa kuthuthukiswa, akukwazi ukuphetha ukuthi kukhona uxhumano lwe-PPI / SIBO / IBS olukhona. Uma unenkinga mayelana nokuxhumeka phakathi kwe-PPI yakho ne-IBS yakho, xoxisana nendaba nodokotela wakho.
Imithombo:
Qhathanisa, D., et.al. "Imiphumela yokwelashwa kwe-PPI yesikhathi eside ekukhiqizeni izimpawu zesisu kanye neSIBO." I- European Journal of Clinical Investigation 2011 41: 380-386.
UJohnson, D. & Oldfield, E. "Imiphumela Ebikiwe Kanye Nezimo Ezibucayi Zokusetshenziswa Kwesikhathi Esiyisikhathi eside se-Proton Pump Inhibitor: Ukuhlakaza Ubufakazi" I-Gastroenterology Clinic ne-Hepatology 2013 11: 458-464.
Bheka, W. & Walter, W. "I-Proton Pump Inhibitor Ukusetshenziswa kanye Nengozi Yokuqothulwa Kwebhaktheriya Emincane Yamathambo: Ukuhlaziywa kwe-Meta" I-Gastroenterology Clinic neHepatology 2013 11: 483-490.
ULombardo, L., et.al. "Ukwanda Kwenyuka Kwezinsizwa Ezincane Zezinambuzane Zezinambuzane Emathunjini Ngaphansi Kweproton Pump Inhibitor Therapy" Gastroenterology Clinical and Hepatology 2010 8: 504-508.
I-Minocha, A. & Adamec, C. (2011) I-Encyclopedia of the Digestive System kanye ne-Digestive Disorders (2nd Ed.) ENew York: Amaqiniso kufayela.