I-Metastases yilokho okwenza umdlavuza ube yingozi. Ukukhula kwamaseli okungalawuliwe kuphazamisa ukusebenza komzimba ovamile. Ezinye izitho, njengezitho zamagciwane , ziqhubeka nokusebenza kahle, ngisho nalapho umdlavuza usakazeka kabanzi. Ngakho-ke, i-lymph node isakazeka yiyona ndlela eyingozi kakhulu yomdlavuza we-prostate umdlavuza. Ngakolunye uhlangothi lwesigubhu isibindi, esivumela kakhulu.
Ukubaluleka kwamathambo asetsheni, indawo ejwayelekile kunazo zonke zomdlavuza we- prostate , isho cishe indlela engamakhilomitha emkhatsini we-metastase ye-node kanye ne-metastases yesibindi. Ngenhlanhla, i-metastases yesibindi iyingqayizivele kakhulu uma umdlavuza we-prostate utholakala kuqala. Izidakamizwa zesibindi ngokuvamile zenzeka ngemva kweminyaka eminingi yokwelashwa okuqhubekayo.
Izinto ezithinta ingozi yezinhlobo ze-Cancer Prostate
Uma ukhuluma ngomdlavuza we-prostate, ngoba igama elithi "umdlavuza" livame ukudala ukwesaba okukhulu, kufanele kuhlale kukhunjulwa ukuthi izinhlobo eziningi ziphansi futhi azikaze zisakazeke. Lezi zigaba ezincane ze-"cancer" zihlukile futhi zimelela isigaba esihluke ngokuphelele sezifo ezingenakukwazi ukuthola imithi. Kodwa-ke, lapho ukhuluma ngohlobo lomdlavuza wesifo sofuba olukwazi ukusabalalisa, izici ezilandelayo zithonya ukuthi kuyingozi kangakanani:
- Isayithi sokusabalalisa, yiliphi isakhiwo esakhele ama-metastases
- Izinga lokusabalala, inani elikhulu lomdlavuza libuhlungu kakhulu.
- Isilinganiso sokukhula kwesisindo se-tumor siboniswa yisikhathi se-PSA sokuphindaphindiwe
- Ukusebenza kokwelashwa okukhona, isici esihlobene nenani lezokwelapha zangaphambilini ezame zamehlo
Njengoba kuphawuliwe ngenhla, isibindi asibekezeleleke kakhulu ekuhlaselweni kwamathambo kunothambo noma i-lymph nodes. Ngaphezu kwalokho, ngenxa yokuthi izidakamizwa zesibindi zivame ukuvela emadodeni anezifo eziphambili, amazinga okukhula kwe-tumor ajwayelekile.
Futhi, ukwelashwa okuvame ukusetshenziswa njengokwelapha i-hormone kanye ne-chemotherapy sekuvame ukuvivinywa kakade. Ukutholakala kwe-metastase yesibindi, ngakho-ke, ukuthuthukiswa okukhulu kakhulu.
Ukuthola ama-Metastase we-Liver
Amagciwane we-foster ngokuvamile aqale ukusola lapho ukuhlola kwegazi lwe-hepatic ye-panel kungavamile. Ukuphenya ngezizathu zokuhlolwa okungavamile kwegazi kuvame ukuholela ekusebenzeni kwe-CT scan noma i-MRI scan, eholela ekusenikeni kwe-metastase esibindi. Ngaphandle kwalokho, ukuskena kungathatha izindawo ezingavamile esibindi kuhlelo olujwayelekile lokuskena kwesikhashana olwenziwa njengengxenye yohlelo lokuhlola okujwayelekile.
Izinketho zokwelapha
Ukwelashwa kwamahomoni noLupron, iZytiga, no-Xtandi, noma i-chemotherapy ne-Taxotere, i-Jevtana ne-Carboplatin, yiyona ndlela evamile yokwelashwa kwe-metastasis yesibindi. Kodwa-ke, lezi zelako kungenzeka ukuthi zazama futhi zilahlekelwa ngempumelelo. Njengoba ukuhluleka kwesibindi kufana nokufa, umdlavuza we-prostate ukukhula esibindi kufanele umiswe, kungakhathaliseki ukuthi lesi sifo sihamba kanjani kuwo wonke umzimba, okungukuthi, amathambo nama-lymph nodes.
Izifundo zingafundiswa emdlalweni wekoloni ngoba izibalo zesibindi ezivela emdlalweni we-colon metastatic zivamile kakhulu.
Ukwelashwa komdlavuza we-colon okuvame ukusetshenziswa kuhlanganisa ukuhlinzeka, ukushiswa kwemisebe nokuvinjelwa kokunikezwa kwegazi kwesibindi ngokufaka umthamo we-arteries, konke okuphumelelayo okuguquguqukayo. Muva nje, ama-microsphres asebenzayo avunyelwe umjovo ekuhlinzekeni kwegazi kwesibindi. I-microspheres ibizwa ngokuthi i-SIR-Spheres. Babonise ukusebenza okuphawulekayo ngemiphumela emibi kakhulu ebekezeleleke.
Umdlavuza we-prostate nomdlavuza we-colon banokufana okufanayo nemisebe. Ngakho-ke, kunengqondo ukucabangela ukuthi i-SIR-Spheres izoba nomthelela wokuvimbela ukuqhuma komdlavuza wesibeletho esibindi.
Ngokomkhuba wami, siye sancoma ama-SIR-Spheres kumagciwane omdlavuza wesifo sofuba we-prostate metastases. Imiphumela iye yakhuthaza ngokuthuthukiswa okuphawulekayo kokuphila kuqhathaniswa nesipiliyoni sethu sangaphambilini kweziguli zomdlavuza we-prostate ezine-metastases yesibindi. Umphumela weziguli eziyisithupha eziphathwe nge-SIR-Spheres zihlelwe ukuthi zizobikwa ngesethulo ku-2016 Symposium ye-Cancers-ASCO Symposium.