Ngesikhathi usufuna ukuphumula okusheshayo ngemuva noma ubuhlungu bezintamo, udokotela wakho cishe uzosikisela ukuthatha imithi yokuhlunguphaza ngaphezulu. Kodwa kunezinhlobo eziningana, futhi ukukhohlisa ukwazi ukuthi yikuphi okumele ukhethe, futhi kungani.
Okokuqala ake sikhulume ngalokho okushiwo yi "izinhlobo" zemithi yokuhlunguphaza ngaphezulu. Lezi zihlukaniswa yi-"isithako esisebenzayo," okuyisisetshenziswa samakhemikhali esenza izinguquko, isibonelo, ukukhulula ubuhlungu, ukunciphisa ukuvuvukala, njll, okushiwo kumalebula okupakisha izidakamizwa. (Izithako ezisebenzayo zingabangela imiphumela emibi, futhi, lokhu kungase futhi kuthathe indima esinqumweni sakho sokuthatha imithi eyodwa ngaphezu komunye.)
Njengoba uzobona, izithako ezisebenzayo zingahle zihlanganiswe zibe izigaba zamachiza. Ngokuqondene nezidakamizwa ezibuhlungu ezingaphezu kwe-counter, amakilasi amabili asemqoka yi-NSAID (ama-non-steroidal anti-inflammatories) kanye nama-analgesics (ukukhululwa ubuhlungu). Ngezinye izikhathi umuthi uzosebenza ngezinhloso zombili; ngezinye izikhathi ngeke.
Zonke kodwa izidakamizwa ezichazwe lapha zi-NSAID ezingaphezu kwe-counter, ezinganciphisa ubuhlungu, ukushisa ukuvutha. I-COX-2 inhibitors, olunye uhlobo lwe-NSAID, lingasiza futhi ekunakekeleni izimpawu zakho, kepha lezi zidakamizwa zitholakala ngomuthi kuphela.
Izidakamizwa eziningi zihambisana nohlu olude lwemiphumela emibi, kanti ama-NSAID awafani. Ezinye imiphumela emibi ye-NSAID ingaba yingozi empilweni yakho; Izingozi ezimbili zokuthatha lezi zinhlobo zezidakamizwa ukuhlaselwa yinhliziyo kanye nezilonda zesisu. Nakubili, bobabili banobubi kakhulu.
Futhi ekugcineni, izidakamizwa ezixoxwe ngezansi ziyatholakala njengemithi kadokotela emazingeni aphezulu.
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AspirinI-aspirin mhlawumbe imithi endala yokuvuvukala eyaziwa ngabantu. I-Acetylsalicylic acid, isithako esisebenzayo ku-aspirin, isetshenziselwe ukukhulisa ubuhlungu emakhulwini eminyaka, uma kungenjalo iminyaka eyizinkulungwane (ngezinhlobo ezahlukene.)
Njenge-NSAID, i-aspirin ingagcini nje ekunciphiseni ubuhlungu emuva noma entanyeni, idlala indima ekulawuleni ukuvuvukala, okungaba usizo ngokulandela ukulimala noma ukulimala.
Isithako esisebenzayo ku-aspirin senza umsebenzi wayo ngokubamba ukukhiqizwa kwe-prostaglandins, okuyimakhemikhali amancane emzimbeni, obhekene nokuvuvukala , kanye nobuhlungu.
Nakuba kungavamile, i-aspirin ingaba nemiphumela emibi kakhulu, hhayi okungenani okungenani izinkinga zesisu. Kodwa ngokungafani namanye ama-NSAID, i-aspirin, uma isetshenziswe ngendlela efanele, kungenzeka ngcono impilo enesifo senhliziyo. Khuluma nodokotela wakho mayelana nalokhu uma ungathanda ukwazi okuningi.
Ngenxa yalokho, ochwepheshe abaningi bakholelwa ukuthi kuwo wonke ama-NSAID, i-aspirin iyona engcono kakhulu. I-Pharmacy Yabantu, okuyinto yombili i-website efundisayo kanye nomsakazo wenkulumo enikezwa kwi-National Public Radio ibeka lesi sitatimende:
"Uma sithunjwa esiqhingini sasehlane futhi singathatha ubuhlungu obulodwa kuphela, singakhetha i-aspirin."
Izizathu, zithi, yilokho kanye nokunciphisa ubuhlungu nokunciphisa ukuvuvukala, i-aspirin iyasiza ukunciphisa ingozi yemicimbi ye-cardiovascular such as heart attach or stroke. Futhi, i-People's Pharmacy ithi, ubufakazi bubonisa ukuthi i-aspirin ingenza izinzuzo zokulwa nomdlavuza, futhi.
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IbuprofenU-Ibuprofen uyisidakamizwa esivimba ukuvuvukala abanye abantu abayithatha ukuze banciphise ubuhlungu obukhulu, ukuzwela, ukuvuvukala nokuqina ngenxa ye-arthritis. Ibuprofen nayo isetshenziselwa ukunciphisa ama-muscle aches kanye nobuhlungu bokuphuza ngenxa yokucindezeleka emuva.
Amagama we-Brand ahlanganisa uMotrin, Advil noNuprin.
Njenge-aspirin, ibuprofen iyi-NSAID, okusho ukuthi akugcini nje ukunciphisa ubuhlungu obunzima noma obuyintamo kodwa idlala indima ekuqukethe inqubo (ukuvuvukala) ngokwayo. Izidakamizwa ezivimbela ukuvuvukala nge-ibuprofen njengezithako ezisebenzayo zivimbela ukukhiqizwa kwe-prostaglandins, ngakho-ke ukuvuvukala nobuhlungu.
Imiphumela emibi ingafaka izinkinga zesisu nemicimbi yezinhliziyo.
Ngo-2015, i-FDA, ngokusekelwe ocwaningweni olusha, imise izidingo zamagama kubakhiqizi kumalebhu we-ibuprofen namalebuli weDrug Facts. Lokhu kwakukwazisa umphakathi mayelana nezingozi ezithile ezihlobene nalesi sithako esisebenzayo.
Esinye sezixwayiso ezibaluleke kakhulu kulokhu kubuyekezwa okusha ukuthi ingozi yokushaya isifo noma isifo senhliziyo ikhona kakhulu ekuqaleni kwenkambo yokwelashwa kunokuba ochwepheshe bekholelwa ekuqaleni.
"Asikho isikhathi sokusetshenziswa esingabonakali ngaphandle kwengozi," kusho uJudy Racoosin, MD, MPH, iphini likamqondisi we-FDA's Division of Anesthesia, i-Analgesia, ne-Addiction Products.
Ukuzivikela ekungenikeleni okungahlosiwe (futhi ngenxa yalokho ingozi eyingozi yemiphumela emibi noma engozini) i-FDA iluleka ukubuka izithako ezisebenzayo kwilebula leDrug Facts lemithi ngayinye oyithathayo, futhi uqiniseke ukuthi eyodwa kuphela yayo iqukethe i-NSAID. Ngamanye amazwi, ungathathi i-NSAID engaphezu kweyodwa ngesikhathi.
Esinye isixwayiso ukuthi labo abavele benesifo senhliziyo, noma abaye bahlinzwa ukuhlinzwa komzimba basengozini enkulu yomcimbi we-cardiovascular ehambisana nokuthatha ibuprofen noma enye i-NSAID.
Uma uke wahlaselwa yinhliziyo, ingozi yakho enye (mhlawumbe ngisho nokufa kwayo) iphezulu, futhi.
Kodwa wonke umuntu, kungakhathaliseki ukuthi isimo saso senhliziyo yempilo siyasengozini enkulu ukuthatha ibuprofen, i-FDA iyasitshela.
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I-NaproxenI-Naproxen , enye i-NSAID, isetshenziselwa ukukhulula ubuhlungu ngenxa yesifo se- muscle ne-arthritis. Lokhu kubandakanya i-osteoarthritis kanye ne-arthritis evuvukalayo njenge-spondylitis e-ankylosing. A
Njengazo ezinye izidakamizwa ezilwa nokuvuvukala, i-naproxen isebenza ngokuyinhloko ngokuvimbela ukwakheka kwe-prostaglandins.
Amagama weBrand ahlanganisa i-Aleve ne-Naprosyn.
Qaphela ukuthi ngenkathi yonke i-NSAID (ene-aspirin engahle ibe khona) iphakamisa ingozi yokuhlaselwa yinhliziyo noma isifo sohlangothi, okungenani isifundo esisodwa sibonisa ukuthi i-naproxen iphakamisa okungenani.
Lokhu kungenxa yokuthi naproxen yisidakamizwa esisebenza isikhathi eside, lapho ibuprofen isebenza khona esifushane. Isidakamizwa eside esisebenzayo akudingeki sithathwe njalo, ngaleyondlela sikwembise ingozi encane yemiphumela yecala yemithi.
Lokho kusho ukuthi iwebhusayithi ehloniphekile, i-Drugs.com, ithi imiphumela emibi ehlobene ne-GI yokuthatha ama-NSAID (isib. Izilonda zesisu kanye / noma ukuphuma) kwandisa isikhathi eside uma uthatha lolu hlobo lwezidakamizwa. Baxwayisa umphakathi ukuba uthathe umthamo ophansi kakhulu okudingekayo ukuletha ukukhululeka kobuhlungu.
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I-Tylenol (i-acetaminophen)I-Tylenol iyinxephezelo evame ukusetshenziswa kakhulu emakethe. Kungathathwa ukuphumula okwesikhashana uma unesihlungu sokubuyisa emuva noma emqaleni. Akuyona i-NSAID.
I-Tylenol isisiza ubuhlungu obuyisifo emuva futhi / noma i- arthritis . Kungase kusebenze ngokunciphisa inani lemikhiqizo yobuchopho elithokozisa izibonakaliso zobuhlungu, ngaleyo ndlela, lithinta isistimu yenzwa yomphakathi . Kubuye kube nomphumela wokupholisa ngokuvimbela i- prostaglandins edlala indima esikhungweni esilawula ukushisa.
Kodwa uma unenkinga yesibindi, noma uma udla utshwala obuningi, kufanele uhambe ngokucophelela uma kuziwa eTylenol. Kulula kakhulu ukuthatha okuningi kwalesi sidakamizwa, okungabangela ukuthi ubuthi obunzima noma obubulalayo bubulawe.
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Ingabe Imithi Yobuhlungu Impela Kuwe?Abalobi besifundo se-2017 eshicilelwe emaphephandabeni e- Medicine ukuthi ngenkathi iningi lezikhalazo ezisezintanyeni nasemuva ezilethwe odokotela zihamba ngokuhamba kwesikhathi, zivame ukubuya (ukuphindaphinda.)
Lobudlelwano obubuhlungu nobuvama bunamandla kakhulu, bathi, phakathi kwezimbungulu zokuqala kanye nezalandela. Ngokucacile, isikhathi eside isiqephu sokuqala siphelile, ubuhlungu obunzima bokubuyela emuva buzobuya kamuva. Futhi isikhathi ngasinye lapho sikwenza, kuyoba nzima kakhulu, futhi kungabangela ukukhubazeka okwengeziwe.
Ngale ndlela, ubuhlungu bakho bokuqala obungakwenzela emuva bungenza okungezansi kube nzima, futhi kungase kube nomthelela esimweni esingapheli esingapheli isikhathi eside, ukuze ubuyekeze.
Abalobi babonisa ukuthi ubuhlungu bomgogodla bungenye yezimo eziyisihlanu ezikhubaza e-US
Njengoba unikezwe konke lokhu, ungase ufune ukuqiniseka ukuthi ukuthatha imithi ngenxa yobuhlungu bakho emuva noma entanyeni nhlobo, empeleni, inkambo yakho enhle kakhulu yezenzo.
Olunye ucwaningo lwango-2017, olushicilelwe ku- Annals of Rheumatic Diseases , uma kuqhathaniswa ukuthatha ama-NSAID ngezinhlungu zesikhala ngokungenzi lutho.
Ngenkathi ama-NSAID azisiza ngobuhlungu, kwakungeyona into eningi. Eqinisweni, abalobi baphetha ngokuthi akukhona neze ama-analgesics ajwayelekile asebenza kahle (uma kuqhathaniswa ne-placebo.)
Futhi uma ubeka engozini yokugaya i-GI kanye / noma izilonda, kanye / noma ingozi ephakeme yokuhlasela kwenhliziyo noma isifo sohlangothi, ungase uthande ukucabangela kabusha isu lakho lokusiza ubuhlungu - ikakhulukazi uma ubuhlungu bakho bubucayi.
Isu esisodwa esithandwa kakhulu ongase uzame ukuzivocavoca.
Ucwaningo olwenziwe ngo-2014 olushicilelwe ku- Ochsner Journal lwathola ukuthi ukuqinisa imisipha ephansi emuva nangeminyango (ekhona ngemuva futhi ikusize umcibisholo kunokuba uguqule noma ujikeleze umgogodla wakho) kusiza ukunciphisa ubuhlungu futhi kungakusiza ukuba usheshe udlule izinhlobo eziningi izinkinga zomgogodla. Uma uya kudokotela ngentamo yakho noma ubuhlungu bomsana, cabanga ukuthatha indlela esebenzayo ngokumcela ukuba abe nomuthi ozoyiphilisa.
> Imithombo:
> Dreisinger, T., PhD. Ukuzivocavoca ekuphathweni kwe-Chronic Back Pain Ochsner J. Spring 2014. https://www.ncbi.nlm.nih.gov/pmc/article/PMC3963038/
> I-FDA Iqinisa Isexwayiso Sokuhlasela Kwenhliziyo kanye Neengozi Yokushaya Izidakamizwa Zezidakamizwa Ezingazange Zisuse Steroidal Anti-Inflammatory. Iwebhusayithi ye-FDA. Kubuyekezwe: Sept 2016. https://www.fda.gov/ForConsumers/ConsumerUpdates/ucm453610.htm
> Graedon, J. Aspirin vs. NSAIDs: Yikuphi Okuhle Kakhulu? I-Pharmacy Yabantu. Julayi 2013. https://www.peoplespharmacy.com/2013/07/08/aspirin-vs-nsaids-which-is-best/
> Machado G., et. al. Izidakamizwa ezingekho-steroidal ezilwa nokuvuvukala ubuhlungu bomgogodla: ukubuyekezwa okuhlelekile nokuhlaziywa kwemeta. I-Ann Rheum Dis. Ngo-July 2017. https://www.ncbi.nlm.nih.gov/pubmed/28153830
> Naproxen vs Ibuprofen: Uyini umehluko? Iwebhusayithi yeDrugs.com. Agasti 2016. https://www.drugs.com/answers/naproxen-ibuprofen-difference-3117722.html
> Sinnott P., et. al. Amathrendi ahloliswe ngezinkinga ezibuhlungu nentamo ebuhlungu, ngo-2002 kuya ku-2011. Imithi (Baltimore). May 2017. https://www.ncbi.nlm.nih.gov/pmc/articles/PMC5440123/