Ukutshala imali isikhathi esithathayo ukuze ufunde izinto eziyisisekelo zokuthatha i-Aleve noma i-naproxen kungakusiza ukugwema imiphumela emibi nezinkinga.
I-Aleve ( isithako esisebenzayo naproxen) imithi engeyona-steroidal anti-inflammatory (NSAID) esetshenziselwa ukukhululeka kobuhlungu, ukunciphisa umkhuhlane, nokuncipha ukuvuvukala. Ngenxa yesenzo sayo sokulwa nokuvuvukala, i-naproxen-noma ngabe ishiwo noma ithengwe phezu kwe-counter- ingasiza njengengxenye yokwelapha kwakho noma ubuhlungu bokubuyela emuva noma isimo somgogodla ohlobene nomgogodla; lokhu kuhlanganisa kokubili i- spondylitis e-ankylosing (uhlobo lwe-arthritis evuthayo) ne-osteoarthritis.
I-Naproxen ingathengwa ngaphezulu kwe-counter esitolo sakho semithi yasendaweni njenge-Aleve brand, noma njenge-generic. Kodwa ngokusekelwe ezimpawu ozenzayo, udokotela wakho anganquma ukuthi umthamo ophakeme ungase uhleleke. Uma kunjalo, angakunika umuthi.
Ungayithatha Kanjani I-Naproxen?
Uma uthatha i-naproxen engaphezu kwe-counter for the pain, izikhombisi-ndlela zokupakisha zizoncoma iphilisi elilodwa amahora angu-8 kuya kwangu-12 uma nje unayo izimpawu. Ilebuli izokutshela ukuthi kuhle ukuthatha amaphilisi amabili ngaphakathi kwehora lokuqala, kodwa ukuthi akuhlakaniphile ukuthatha okungaphezu kokubili kunoma yisiphi isikhathi sehora lesishiyagalolunye kuya kwezingu-12, noma amathathu kunoma iyiphi ihora le-24.
I-Drugs.com incoma ukuthatha u-440 mg ngomlomo ngehora lokuqala njengoba kudingeka, bese u-220 mg ngomlomo njalo amahora angu-8 kuya kwangu-12, futhi, njengoba kudingeka. Bathi futhi isilinganiso esiphezulu akumele sibe ngaphezu kuka-440 mg kunoma yisiphi isikhathi sehora lesishiyagalombili kuya ku-12, noma 660 kunoma iyiphi ihora le-24.
Izinto zishintsha uma udokotela wakho ebeka naproxen ngentamo noma emhlane. Kulokho, i-Drugs.com ithi i-naproxen yokuqala ye-naproxen ephakanyisiwe ingaba phakathi kuka-500 no-1000 mg, kuye ngokuthi ithebhulethi iyisikhulu esivela ngokushesha noma uhlobo olulawulwayo lokukhululwa. Bathi futhi amaphilisi okulibala okulibala alikhuthazwa ubuhlungu obukhulu.
Ngemuva kwalolo dolobha lokuqala (kodwa ngosuku lokuqala) isincomo sithathe 275 mg we-tablet yokukhululwa ngokushesha ngomlomo njalo ngamahora ayisithupha kuya kwangu-8, noma ama-550 ngomlomo njalo ngamahora angu-12 njengoba kudingekile ukuthambisa izimpawu. Kodwa khumbula ukuthi umthamo omkhulu we-tablet yokukhululwa ngokushesha owathathwa ngosuku lokuqala ngu 1375 mg. Ezinsukwini ezilandelayo, ngu-1100 mg.
Amathebhulethi alawulwa ngosuku lokuqala (ngemuva kwesilinganiso sokuqala), ungakhula kufika ku-1500mg. Kodwa ngezinsuku ezilandelayo, isincomo siwuletha umthamo phansi kuze kube ngu-1000mg noma ngezansi.
Qaphela ukuthi umthamo owodwa we-Aleve uqukethe i-napmx 200mg ne-sodium engu-20mg.
Ulwazi lwe-Naproxen Dosage Information for Arthritis Related Spine Conditions
I-osteo kanye / noma i- arthritis evuthayo, amanani we-naproxen anconyiwe aphansi.
Uma kuziwa amaphilisi okukhululwa ngokushesha, i-Drugs.com ithi ithathe phakathi kuka-250 no-500mg ngomlomo kabili ngosuku. Khona-ke, kusukela ngosuku lwesibini, ungakwazi ukwandisa umthamo ube ngu-1500mg ngomlomo. Kukhona isixwayiso kwezinye iziguli-le mali yesilinganiso ingaphephile kuphela ezinyangeni eziyisithupha.
Ingabe uthatha (noma ucabange ukuthatha) naproxen for spondylitis ankylosing? Uma kunjalo, umthamo ophakanyisiwe we-750mg kuya ku-1000mg ngomlomo kanye ngosuku, noma ku-375 kuya ku-500mg ngomlomo kabili ngosuku.
Futhi ngenxa ye-osteoarthritis, isincomo siphakathi kuka-750mg kuya ku-1000mg ngomlomo kanye ngosuku.
Ukukhohlwa ukuthatha i-Naproxen
Uma ulahlekelwa umthamo, thatha owodwa ngokushesha uma ukhumbule. Okungafani kuyoba yilapho sekusele isikhathi esilandelayo. Uma kunjalo, vele ulinde kuze kube yisikhathi sokuyithatha futhi. Hlala usondelene nesimiso sakho sokulinda njalo futhi ungalokothi wenze umthamo ophindwe kabili lomuthi.
Ukugcina i-Naproxen
Gcina ngokuvikelekile i-naproxen yakho ngokuyigcina ivalwe ngokuqinile kulesi sitsha, ngaphandle kokushisa nokuswakama. Lokhu kusho ukuthi awuyikugcina endlini yokugezela. Futhi, i-naproxen kufanele igcinwe ekamelweni lokushisa. Yilahle uma iphelelwe yisikhathi, noma awusayidingi.
Ungabuza umuthi wakho wemithi indlela engcono kakhulu yokwenza lokho. Gcina naproxen ekufinyeleleni kwezingane.
Mechanism Action Action kaNaproxen
Yonke imithi eklasini le-NSAID, kufaka hlangana ne-naproxen, umsebenzi ikakhulu ngokuvimbela ukwakheka kwamakhemikhali emzimbeni owaziwa ngokuthi i- prostaglandins . Lena indlela eyinhloko umuthi oletha ukukhululeka. (Uma kwenzeka unesithakazelo, i-prostaglandin yizinto ezibangela, phakathi kwezinye izinto, ukukhiqiza ukuvuvukala nobuhlungu obuphumela kulo.)
Ukucatshangelwa kokuphepha kwe-Naproxen
Iningi labantu-kuhlanganise nabaningi bezempilo abanezensifiketi-banomqondo wokuthi ukuthatha i-naproxen ngokuvamile kuphephile.
Kungakhathaliseki ukuthi uyayibona noma cha, noma kunjalo, isithako esisebenzayo ku-naproxen asifanele wonke umuntu. I-Naproxen iye yahlotshaniswa ne-GI tract, futhi isifo esibi kakhulu, ngisho nesifo esibulalayo, nezinkinga zenhliziyo. (Sizokhuluma ngokujulile ngalokhu ngezansi.)
Ngenxa yokuthi imiphumela emibi ehlobene nalesi sidakamizwa sobuhlungu ngokuvamile ibuhlungu ngokwemvelo, kungcono ukuthatha kuphela inani elidingekayo, ngoba isikhathi esifushane kunesidingo.
Udokotela wakho ungumuntu ongcono kakhulu ukukusiza ukuthi unqume ukuthi ungakanani nokuthi uthatha kangakanani (njengokunye nanoma yisiphi isidakamizwa). Uma engatholakali ukukhuluma nawe, landela imiyalelo ephaketheni ngokucophelela, futhi / noma ubuze umuthi wakho wezemithi. Kodwa ungathathi okungaphezulu kunani eliphakanyisiwe, bese unamathela kumvamisa ophakanyisiwe.
Izingozi ezingasese ezimbi kakhulu
Njengoba ubuhlungu obukhulu obukhulu bokuphumula nobuhlungu obuvuvukalayo, i-naproxen ingase ibe nengozi enkulu kakhulu empilweni yakho.
Okokuqala, kukhona amandla okuba nomphumela wokuziphikisa. Lokhu kungaboniswa njengama-hives, ukuvuvukala komzimba, isifuba somoya, ukuqhuma kwesikhumba, izibhansela, noma ukushaqeka. Uma ngisho neyodwa yalezi zimpawu zenzeka, yeka ukuthatha naproxen futhi ufune usizo lwezokwelapha oluphuthumayo.
Okulandelayo ngumphumela owaziwa kakhulu futhi ojulile wesisu sokuphuma kwegazi. Kubalulekile ukuhlala uqaphele-uma uthola izimpawu noma izimpawu zokuphuma kwegazi, funa ukwelashwa ngokushesha. Ukwenza kanjalo kungasindisa impilo yakho.
Okwesithathu yiphrofayili engozini yempilo yenhliziyo yokuthatha noma iyiphi i-NSAID. Ngokusho kukaGregory Curfman, MD, uMhleli oyiNtloko, iHarvard Health Publications, siye sabona, eminyakeni engaba ngu-12 edlule, ubufakazi obusukayo bokuthi ukuthatha ama-NSAID bubeka ingozi esimisweni sakho senhliziyo. Izingozi zezempilo azibhekisela kuzo zihlanganisa ukuhlasela kwenhliziyo, ukwehluleka kwenhliziyo nokushaya; ingozi ehlobene nayo yaphakamisa umfutho wegazi.
Ngokusekelwe ekutholeni ucwaningo, i-FDA, ngo-2015, idinga abakhiqizi ukuba baqinise izixwayiso zabo mayelana nalezi zingozi zezempilo ze-CV kumaPhakheji we-NSAID nokubhala. Ukubhaliwe manje kufanele kukutshele ukuthi ingozi yakho yokuhlaselwa inhliziyo kanye nokushaya isifo kungakhula, noma ngabe usebenzisa ama-NSAID kuphela amasonto ambalwa, nokuthi ukuphakama okuphezulu okuthathwe isikhathi eside kungase kube inkinga.
U-Curfman uphinde ubike ukuthi iziguli ezitholakale zinezifo zenhliziyo, ukuthatha naproxen cishe akuwona umbono omuhle. Lokhu kungase kwande, uthi, labo abangenayo isifo senhliziyo esaziwayo.
Lokho kusho ukuthi ngenkathi isifundo seDanishi sika-2016 sathola ukuhlangana phakathi kwe-ibuprofen yesikhathi esifushane noma ukwelashwa kwe-diclofenac kanye nengozi yokuqala yomcimbi we-cardiovascular, abazange bakwazi ukubona noma yikuphi ubudlelwane phakathi kwe naproxen kanye nemicimbi. I-aspirin isabhekwa njengengozi ephansi yeNSAID.
Izimpawu okumele zibheke lokho zingase zibonise umcimbi we-cardiovascular zihlanganisa ukusakazwa noma ukuzwa okuhlobene nenhliziyo yakho, njengobuhlungu besifuba, ubuthakathaka, ukuphefumula, inkulumo ehlelekile noma izinkinga noma ibhalansi. Ukugcinwa kwe-Fluid esinye isibonakaliso udinga ukwelashwa okusheshayo ngokushesha.
Ezinye Imiphumela Ezingenzeka Ezingenzeka
Ukulimala kwesibindi kungenye inkinga engaba khona yokuthatha i-naproxen noma enye i-NSAID. Izimpawu zenkinga yesibindi zibandakanya ukunxanxathela, ukuhlanza, ukulahlekelwa ukudla, ukuchiza, ukuphuza isikhumba kanye / noma amehlo, izimpawu ezifana nomkhuhlane kanye nomchamo omnyama. Uma unezinye zazo, yeka ukuthatha naproxen futhi ufune ukwelashwa ngokushesha.
Futhi ekugcineni, nansi uhlu lweminye imiphumela emibi engase ibe yinto engavamile noma engaphezulu kakhulu kunelabo esiye sakhuluma ngenhla. (Qaphela ukuthi uhlu aluphelelanga, ngakho-ke uma ufuna ulwazi oluthe xaxa hlola i-Drugs.com.) Khuluma nodokotela wakho ngokushesha uma ungazikwazi uma ngabe enye yalezi zimpawu isebenza kuwe:
- ukuqotshwa , isifo sohudo noma igesi
- izilonda emlonyeni
- usomile kakhulu
- ikhanda
- i-dizzy noma ikhanda elincane
- belele
- izinkinga zokulala
- ukushisa noma ukugubungula ezandleni noma emilenzeni
- uzizwa sengathi unomkhuhlane
- ukukhala ezindlebeni noma ezinye izinkinga zokuzwa.
Ingabe Kufanele Uthathe I-Naproxen?
Kungaba sobala manje ukuthi ngenxa yesithombe sakho sezempilo jikelele kanye nocwaningo olusha kumaNSAIDs naproxen akuyona indlela yakho engcono kakhulu yokuphumula kobuhlungu.
Yiqiniso, uma usuvele unezimo ezishiwo ngaphambilini (isifo senhliziyo, isifo, izinkinga zamathunjini, izinkinga zesibindi) ukuthatha i-naproxen cishe akuwona umbono omuhle nhlobo, ngoba uzophakamisa ingozi yokufa okuhlobene. Kodwa nansi ezinye izinto ezimbalwa.
Ingabe ukhulelwe noma uhlela ukukhulelwa? Uma kunjalo, kufanele ukhulume nodokotela wakho ngaphambi kokuba uthathe naproxen. Lesi sidakamizwa singabangela ukukhubazeka kokuzalwa uma kuthathwa ku-trimester yokugcina yokukhulelwa. Kungase kudlule ubisi lwebele kumntwana okhulelwe futhi kwenze umonakalo.
Kule migqa, ukunikeza i-naproxen kwengane engaphansi kweminyaka engu-2 akukhuthazwa, ngaphandle kokuqondiswa udokotela wakho.
Ngokusobala uma unomlando wezinkinga zenhliziyo, ama-blood clots, ukucindezela kwegazi eliphezulu, isifo sohlangothi, izinkinga zezinso, ama-clots wegazi noma izilonda zesisu, ukucabanga kabusha nge-naproxen cishe kuyisithakazelo sakho. Nalapha, lokhu kungenxa yokuthi kungaphakamisa ingozi yakho ngomcimbi we-cardiovascular, noma ukufa. (Bheka ngezansi ukuze uthole okunye okucacile.) Futhi ukuthatha noma iyiphi imikhiqizo ye-naproxen ngaphambi noma ngemva kokusebenza kwenhliziyo okungavunyelwe.
Njengoba sikhuluma ngenhla, ama-NSAID afika engozini yezilonda, ukuphuma egazini esiswini nezinye izinkinga ze-GI. Lemiphumela emibi kakhulu kakhulu. Khumbula ukuthi kungenzeka nganoma isiphi isikhathi, futhi kungabonisa ngaphandle kokuxwayiswa kwangaphambilini. Izakhamuzi eziphezulu zingase zibe sezingeni eliphezulu kakhulu. Ngakho-ke uma usuvele unenkinga ye-GI, sebenza nodokotela wakho ukuze uthole isisombululo esifanele sokusiza ubuhlungu.
Futhi, ukuphuza ne-naproxen akuxubeki. Ukusetshenziswa kotshwala ngokuhlanganiswa ne naproxen enye enye indlela yokwandisa ingozi yezinkinga zesisu ne-GI.
Ezinye izimo ezingakwandisa ingozi yokuthi imiphumela emibi yocala ye-naproxen ihlanganisa i-asthma, i-polyps ekhaleni, i-bleeding ne-clotting disorders, ukubhema, isikhumba esibhekene nokukhanya kwelanga, futhi njengoba sekubhekene nezinkinga zezinso nezinso zesibindi noma izinkinga.
Ukusebenzisana kwezidakamizwa nokudlula ngokweqile
Sesivele sitshele kancane mayelana nokuxuba utshwala kanye naproxen; lokho akusikho-cha! Kodwa uma uthatha ezinye izinhlobo zemithi, kungakhathaliseki ukuthi (futhi) izidakamizwa zobuhlungu noma izidakamizwa ezibandayo / ezibangelwa ukuphuza izifo ungaqeda ukudlula ngokweqile. (Imithi eminingi ye-OTC iqukethe ama-NSAID, yize lokho kungewona uhlobo lwesithako esisebenzayo esitholakala kwizikhangisi, noma kuma-shelf ekhemisi.) Ngenxa yalesi sizathu, kubalulekile ukuthi ufunde wonke amalebula wezokwelapha (i-OTC neyemisiwe) ngaphambi kokuwaxuba. Qiniseka ukuthi uthola umthamo owodwa kuphela we-NSAID ngezikhathi ezifanelekile (njengoba kuchazwe ekuqaleni kwalesi sihloko.)
Uma ucabanga ukuthi kungenzeka ukuthi usule ngaphezulu, shayela u-911 noma isikhungo sakho sokulawula ubuthi.
Yikholelwa noma cha, ukuxuba izithako zokudla okunomsoco, amakhambi, izidakamizwa zokuzilibazisa, kanye / noma ikhofi ingaxhumana ne-naproxen futhi ishintshe indlela esebenza ngayo emzimbeni wakho. Khuluma nomhlinzeki wakho wezempilo mayelana nemali yesilinganiso semithi ngayinye kanye / noma enye yokunciphisa ubuhlungu.
Futhi njalo ukhulume nodokotela wakho uma ufuna noma kudingeka uyeke ukuthatha noma yimiphi imithi.
Kanye nezidakamizwa nezinye izinto esivele zixoxwe kulesi sihloko, ngezansi uhlu lwemithi engase ihlanganyele ne naproxen ngendlela engafanele. Qinisekisa ukuthi uthintana nodokotela wakho noma umuthi wemithi uma enye imithi yakho noma kulolu hlu, noma uma uthatha enye imithi noma izidakamizwa:
- utshwala
- i-alendronate, ethathwe ukuvimbela ukulahlekelwa kwethambo
- amanye ama-NSAID, afaka i- aspirin . Uma usebenzisa i-aspirin isikhathi eside, amathuba akho okuphuma kwegazi asanda.
- ezinye izidakamizwa eziphikisayo (njenge- ibuprofen noma i-prednisone)
- i-entecavir, ye-hepatits-B izifo
- i-cidofovir, ethathwe ukutheleleka kweso ezigulini ze- HIV
- i-cyclosporine, eyanikezwa ukufakelwa iziguli
- amaphilisi amanzi (i- diuretics )
- imithi yegazi, njenge-ACE inhibitors
- igazi elincane njengeCoumadin, noma iminye imithi yokuphatha noma yokuvimbela i-blood clots
- methotrexate, i-chemotherapy izidakamizwa
- pemetrexed, imithi ye-chemotherapy
- imikhiqizo yemifino equkethe i-feverfew, i-garlic, i-ginger, noma i- ginkgo biloba
- imithi ye-lithium njenge-Eskolith Lithobid
Izwi elivela
I-Naproxen ingase ibe usizo esimweni sakho, kodwa ukuze usebenzise okungcono udinga ukuyisebenzisa ngokuphepha. Kungakhathaliseki ukuthi uthola i-naproxen yakho phezu kwe-counter noma njengomshwalense ovela kudokotela wakho, qiniseka ukuthi ulandela imiyalelo yokulinganisa futhi uqaphele imiphumela emibi kanye nokusebenzisana. Uma unomuzwa wokuthi okuthile akulungile, xhumana nodokotela wakho.
> Imithombo:
> Curfman, G., MD, Umhleli oyiNhloko. I-FDA iqinisa isixwayiso sokuthi ama-NSAID akhula ukuhlaselwa kwenhliziyo kanye nobungozi bokushaya isifo. I-Harvard yezempilo Publications. I-Harvard Medical School. July 2015. http://www.health.harvard.edu/blog/fda-strengthens-warning-that-nsaids-increase-heart-attack-and-stroke-risk-201507138138
> Naproxen. Iwebhusayithi yeDrugs.com. Kugcine ukubuyekezwa: ngo-Ephreli 2017. https://www.drugs.com/naproxen.html
> Sondergaard KB, Weeke P, Wissenberg M, et al. Ukusetshenziswa kwezidakamizwa ezingezona ukuvuvukala kwezidakamizwa kuhlotshaniswa nengozi eyengeziwe yokuboshwa komzimba ngaphandle kwesibhedlela: isifundo se-case-control-time national. I-European Heart Journal - I-Pharmacotherapy ye-Cardiovascular. Ngomhlaka 2016. https://academic.oup.com/ehjcvp/article/doi/10.1093/ehjcvp/pvw041/2739709/Non-steroidal-anti-inflammatory-drug-use-is