Yini Ongayithola Ngokuthatha i-Amitriptyline yokuvimbela iMigraines
I-Amitriptyline (Elavil), i-tricyclic anti-depressant, isetshenziselwa ukuvimbela imigraines . Masifunde kabanzi mayelana nale mithi, kuhlanganise nemiphumela yaso engenzeka.
Ingabe i-Amitriptyline iphumelela ekuvimbeleni i-Migraines?
Kubonakala sengathi i- amitriptyline iyasebenza, nakuba kunezifundo ezimbalwa zesayensi eziqhathanise i-amitriptyline ne-placebo.
Ucwaningo olulodwa luka-2011 eNhloko ye-Headache , lithole ukuthi i-amitriptyline yayiphumelele ekuvimbeleni i-migraines uma iqhathaniswa ne-placebo emavikini ayisishiyagalombili wokusetshenziswa, kepha hhayi emavikini angu-20.
Kwesinye isifundo se-2009 ku- Clinical Therapeutics , kokubili i-Topamax ne-amitriptyline zitholakale zifana nokusebenza kahle ekuvikeleni imithi ye-episodic migraines. I-Topamax i-FDA-ivunyiwe njengemithi yokuvimbela i-migraine kanti i-amitriptyline ayilona - iyasetshenziswa ngaphandle kwelebuli.
Iyini i-Downside ye-Amitriptyline ekuvimbeleni i-Migraines?
Ukuphazamiseka ukuthi i-amitriptyline ibangela ezinye imiphumela emibi ukuthi ngezinye izikhathi ibangela abantu ukuba bayeke. Lezi zingabandakanya: umlomo owomile , ukukhathala , ukungahlali kahle , ukuzuza isisindo , isizungu , ukuqotshwa , isifo se- orthostatic hypotension - ukwehla komfutho wegazi lapho umuntu ehamba esuka endaweni yokubeka noma ehlezi endaweni yokuma.
I-Amitriptyline ingase futhi ikhulise ingozi yomuntu yokwehla kwamathambo , futhi ibangele ukwehla kwenani lamaseli egazi, nakuba lokhu kungavamile.
U-Amitriptyline angabuye ahlanganyele nemithi eminingi - ngakho-ke qiniseka ukuthi uyazisa udokotela wakho yonke imithi, izithako ezingaphezu kwe-counter, kanye namavithamini.
Ngaphezu kwalokho, sicela uzise udokotela wakho wonke umlando wezokwelapha. I-Amitriptyline kufanele igwenywe noma isetshenziswe ngokuqapha kubantu abanomlando wesifo senhliziyo, inhliziyo noma isigqebhezana esingavamile, isifo sikashukela, isibindi noma ukukhubazeka kwezinso, ukuphazamiseka kwe-bipolar, i-seizure disorder, i-angle-angle-angle glaucoma, amehlo anomile noma izinkinga zombono, wehla ubunqunu bomzimba, ukugcinwa kwe-urinary noma i-prostate ekhulisiwe.
Okokugcina, njengamanye ama-anti-depressants, i-amitriptyline ingathuthukisa imicabango yokuzibulala noma ukuziphatha. Qinisekisa ukuthi uxhumane nodokotela wakho ngokushesha lapho kukhona nemiphumela emibi, ngisho nalawo ongakhulumanga, ayaphazamisa noma aphikelela. Shayela u-911 esimweni esiphuthumayo.
Okunye ukuqapha nge-Amitriptyline:
- Kubaluleke kakhulu ukuthi udokotela wakho ahlole inqubekelaphambili yakho ngokuvakashelwa njalo ukuvumela ukulungiswa kwesilinganiso kanye nokusiza ukunciphisa imiphumela emibi.
- Lo muthi uzokwengeza emiphumeleni yotshwala nezinye izidakamizwa ze-CNS.
- Lo muthi ungabangela ubuthongo. Uma lokhu kwenzeka, ungadlulisi, sebenzisa imishini, noma wenze noma yini enye engaba yingozi uma ungaqaphile.
- Ama-anti-depressants e-Tricyclic angabangela isikhumba sakho ukuba sithandeke kakhulu ekukhanyeni kwelanga.
- Ungayeki ukuthatha le mithi ngaphandle kokuhlola kuqala nodokotela wakho.
- Imiphumela yalo muthi ingadlulela izinsuku ezintathu kuya kwezingu-7 ngemuva kokuyeka ukuyithatha.
Lokho Kusho Ngami?
I-Amitriptyline iyinqubo ephumelelayo yokuphulukisa imithi yabantu abaningi. Lokhu kuthiwa, kuwukuhlakanipha nokukwazi ukuthola imiphumela emibi, njengalezo zonke izidakamizwa. Ngale ndlela ungaqiniseka ukuthi uyayithatha ngokuphepha. Njengoba njalo, qiniseka ukuthi uxoxisana nazo zonke izikhathazo nemibuzo nodokotela wakho.
Imithombo:
I-Couch JR & Amitriptyline Versus Studybo Group Group. Izinwele . 2011 Jan; 51 (1): 33-51.
I-Dodick DW et al. I-Topiramate ngokumelene ne-amitriptyine ekuvimbeleni kwe-migraine: isonto eli-26, eliningi, elingahleliwe, eliphindwe kabili-eliyimpumputhe, eliphindwe kabili-i-double-dummy, le-parallel-group trial non-feriority ku-migraineurs yabantu abadala. I-Clin Ther. 2009 Mar; 31 (3): 542-59.
Lexicomp Online. Amitriptyline. Ibuyiselwe ngo-Novemba 25th 2015.
Shamliyan TA et al. Imithi yokwelapha evikelayo ye-epradic migraine kubantu abadala. J Gen Intern Med . 2013 Sep; 28 (9): 125-37.
Ukuziphendulela: Izinto ezikuleli khasi zenzelwe izinjongo zokwaziswa kuphela, futhi akufanele zithathwe njengeseluleko sezokwelapha. Njalo thintana nodokotela wakho mayelana nemithi.