Amapulazi Akho Awona Amalungu Ezimba Zodwa Ezihlupheka
Ukubhema ugwayi kuthinta zonke izingxenye zomzimba, kubandakanya uhlelo lokugaya . Lokhu kulimaza ikakhulukazi ngoba uhlelo lokugaya lusebenzisa ukudla esikudla kuwo izinto ezidingekayo ukuze umzimba usebenze kahle. Ngokuyinhloko, abantu abanesifo sikaCrohn (uhlobo olulodwa lwesifo sofuba , noma i-IBD) basengozini yokuthi isifo sabo sibi nakakhulu uma bebhema.
Izifo zika Crohn
Ukubhema ugwayi kunomthelela omubi kwisifo sikaCrohn. Abantu ababhema, noma ababhemayo esikhathini esidlule, baye baboniswa ukuthi banengozi ephakeme yokuthuthukisa isifo sikaCrohn kunabantu abangabhemi. Abantu abanesifo sikaCrohn ababhemayo banenombolo ephindaphindiwe yokubuyela emuva (ukuhlaselwa) futhi baphinde bahlinzekwe, kanye nesidingo esikhulu sokwelashwa nokuhlukunyezwa ngezidakamizwa ezibizwa ngokuthi imithi yokuzivikela.
Akekho owaziyo ukuthi kungani ukubhema kuphazamisa inkinga yesifo sikaCrohn. Kuthiwa ukuthi ukubhema kunganciphisa ukugeleza kwegazi emathunjini noma ukuthi kungabangela impendulo kwisistimu yomzimba. Ngisho nangemva kokuyeka ukubhema, lowo owayekade ebhema naye usengozini yokuthuthukisa isifo sikaCrohn. Nokho, kunenzuzo kubantu abane-Crohn's disease abayeka ukubhema. Unyaka ngemva kokuyeka ukubhema, ababhemayo ababenesifo sikaCrohn bangase babe nesimo esibucayi sesifo.
Ukuguquka kwenhliziyo
Ukuphuza isisu kungabangelwa nokubhema. I-valve ekupheleni kwesifo (i-sphincter engaphansi, noma i-LES) ihlale igcina isisu se-acids ukuze ibuye iphinde iphinde ibe khona. I-LES ibuthakathaka ngokubhema, okubangela ukuthi isisu se-acid sikwazi ukufaka isisu futhi kubangele ukuqubuka kwenhliziyo.
Ukubhema kubuye kubonakale kukulimaza ngokuqondile, okuvimbela ikhono layo lokulwa nomonakalo. Ukwengeza, ukubhema kuphazamisa ukuhamba kwama-salts e-bile. Amanoni ahamba ngamathumbu asuka emathunjini kuya esiswini. Uma lokhu kungenzeki (isifo esibizwa ngokuthi i-reflux ye-duodenogastric) isisu se-isisu siyaba namandla futhi singalimaza kakhulu umgogodla.
Izifo zesibindi
Esinye isici emgudleni wokugaya okungathinteka kakhulu ukubhema yisibindi . Isibindi siyilungu ebalulekile elihlunga ubuthi emzimbeni. Lezi zinhlayizi zihlanganisa imithi neziphuzo ezidakayo. Umsebenzi wesibindi ungavinjelwa umusi wesigayi. Uma kwenzeka lokhu, kudingeka umthamo ohlukile wemithi ukuze ufinyelele umphumela oyifunayo ekuguleni noma ngesifo. Ukubhema kungabuye kukhulise izifo zesibindi ezikhona ngenxa yokudakwa ngokweqile.
Abantu abane-IBD nabo bangengozi enkulu yezifo ezithile zesibindi, njenge- primary sclerosing cholangitis (etholakala ngokuyinhloko kulabo abane-ulcerative colitis), i-autoimmune hepatitis, kanye ne-primary cirrhosis ye-biliary. Ingozi engaba khona yesifo sebindi yisinye isizathu esenza abantu abane-IBD bangabhemi.
Ulcer Peptic
Ababhemayo banethuba eliphakeme lokuthuthukisa isilonda (umgodi esiswini).
Uma umuntu obhemayo ethola isilonda, ngokuvamile kuthatha isikhathi eside ukuphulukisa futhi unethuba elikhulu lokubulala kunabangaboni. Akekho oqiniseka ukuthi kungani kunjalo, kodwa kungenzeka ngenxa yezimo ezihlukahlukene zokubhema kupheshana lokugaya. Ukubhema kunciphisa inani le-bicarbonate ye-sodium eyenziwa yi-pancreas. Ngaphandle kwalo, isisu se-asidi asikhiphi emzimbeni we-duodenum (ingxenye yokuqala yomathumbu amancane ). Lokhu kungabangela izilonda ezenza i-duodenum. Futhi, ukubhema kungabangela ukwanda kwesisindo se-esiswini esigeleza ku-duodenum.
Izwi elivela
Ukubhema kubangela ukulimala okungathí sina futhi ngezinye izikhathi ezingenakuguqulwa kwindlela yokugaya.
Kulinganiselwa ukuthi abantu abangu-400 000 bafa ngonyaka ngamunye ngenxa yokubhema ugwayi. Lezi zokufa, nokuhlupheka okuphambi kwazo, ziyakwazi ukuvimbela ngokuphelele izinhlelo zokuqeda ukubhema.
I-IBD nokubhema kunobungane obuseduze, futhi abantu abane-Crohn's disease ikakhulukazi kufanele bayeke ukubhema ukuze bavimbele isifo sabo ukuba singabi sína futhi sibangele ukucindezeleka. Abanye abantu ababengenayo izinkinga ngenkathi bebhema baba nesifo socansi emva kokuyeka ukubhema. Kodwa lokho akusho ukuthi kuphephile ukuqala ukubhema futhi. Ukulimala empilweni okubangelwa ukubhema kuzohlale kukhulu kakhulu kunoma yikuphi okukhona "izinzuzo." Abantu, ngokujwayelekile, akufanele bashunqe, kodwa abantu abane-IBD kufanele baqaphele ikakhulukazi izinkinga zokugaya ukudla okuzobangela.
Imithombo:
UJohnson GJ, Cosnes J, uMansfield JC. "Isihloko sokubukeza: ukuyeka ukubhema njengokwelapha okuyisisekelo ukushintsha inkinga yesifo sikaCrohn." Ukudla Pharmacol Ther. 2005 Apr 15; 21: 921-931.
Cosnes J, Beaugerie L, uCarbonnel F, uGendre JP. Ukuyeka ukubhema kanye nenqubo yesifo sikaCrohn: isifundo sokungenelela. "I- Gastroenterology Apr 2001.
I-National Digestive Diseases Information Clearinghouse. "Ukubhema Nendlela Yakho Yokugaya." Isikhungo Sikazwelonke Sesifo Sikashukela Nesifo Sezinyosi Nezinso 14 Septhemba 2013.
I-Yamamoto T. "Izinto ezithinta ukuphindaphinda ngemuva kokuhlinzwa kwesifo sikaCrohn." World J Gastroenterol 14 Jul 2005.