Ukucwaninga Ngendlela Izithako Zokudla Zithinta Ngayo Ama-IBD Okungavumelani
Kulokhu kube khona inani elikhulu lokucabangela elizungeze ukuthi ukudla okunengi kuthinta kanjani ukuthuthukiswa kanye nenkambo yezifo zesifo sofuba (IBD) . Kubonakala kunengqondo ukuthi ukudla kuzoba nethonya kwisifo esibangela izimpawu ezitholakala emgodini wokugaya ukudla, kodwa kuze kube manje awukho ubufakazi obunamandla bokuthi kungani lokhu kungenzeka noma ukuthi kwenzekani nakanjani.
Ukudla kuyinkinga ekhangayo, futhi abantu abanesifo sikaCrohn kanye nesifo sokulonda kwesilonda bavame ukutshala izimali ngendlela yokudla okungase kungathinteki noma kungathinti izimpawu zabo. Njengoba ubudlelwane obuphakathi kokudla kanye ne-IBD bufundwa ngokuqhubekayo, ucwaningo oluthile ngesihloko luvame ukudala kancane inzwa lapho lishicilelwa.
Ubuhlobo phakathi kwe-colitis (ukuvuvukala emgqonyeni) kanye nesithako sokudla esibizwa nge-titanium dioxide yinkinga eyodwa enjalo. Okwamanje akukhona ubufakazi obuningi obukhomba ukuxhumana phakathi kwe-IBD ne-titanium dioxide. Kodwa-ke, kukhona ucwaningo lwesigaba sokuqala olungase luholele ekutadisheni okwengeziwe kuze kube nokuqonda kangcono ukuthi lezi zinhlobo zezidakamizwa zokudla, ezingase zikhulunywe ngokuthi njenge-nanoparticles noma ama-microparticles, zingase zihlanganyele ne-IBD. Njengamanje, azikho izincomo ezibanzi kubantu abane-IBD ukugwema izithasiselo zokudla, futhi abantu abane-IBD abanezinkinga kufanele bacele udokotela wabo ngezincomo zokudla.
Iyini i-Titanium Dioxide?
I-Titanium dioxide (TiO2) iyi-nanoparticle eyinhlanganisela esetshenziselwa ukudla, imithi, imikhiqizo yabathengi, nemikhiqizo yokunakekelwa yomuntu, njengezimonyo. Kuyinto into emhlophe engenza imikhiqizo ibonakale icacile noma imhlophe, njengezithunzi zamehlo, i-powder okuxekethile, iphepha, noma ngisho ne-cake frostings.
I-Titanium dioxide isetshenziselwa ukuhlunga i- UV (ultraviolet) emasimini e-sunscreen ukuze ivikele isikhumba ekushiseni kwelanga. Ngakho-ke, lo ngumkhiqizo odliwa ngabantu ekudleni noma ngemithi futhi ubeke emzimbeni futhi ungene esikhumbeni, njengezimonyo noma ama-sunscreen.
Uma i-titanium dioxide isetshenziselwa imithi, isithako esingasebenzi , futhi ngezinye izikhathi sibizwa ngokuthi i-excipient. Isithako esingasebenzi esingasetshenziswa emithi ngezizathu ezihlukahlukene, noma "ukusiza" isithako esisebenzayo noma ukwenza ukubukeka kwemithi noma ukunambitha kangcono. Isetshenziselwa ngoba akufanele kube nesenzo emzimbeni.
I-titanium dioxide ivela ngokwemvelo kepha ibuye idale umuntu. Incazelo yokubunjwa kwamakhemikhali we-titanium dioxide ingathola ubuchwepheshe obukhulu ngoba kunezinhlobo ezahlukene. Abakhiqizi abadingeki ukuba babhale uhlobo lwe-titanium dioxide esetshenziselwa imikhiqizo, futhi linamagama amaningi okuhweba.
Iphephile kangakanani i-Titanium Dioxide?
I-Titanium dioxide ivunyelwe ukusetshenziswa kokudla, imithi, nezimonyo, ngakho kubhekwa njengokuphephile izinhlangano zikahulumeni ezivumile ukusetshenziswa kwazo. Inani elisetshenziselwa imikhiqizo lizohluka, kepha ngokuvamile alikhulu. Ukusetshenziswa kwayo emhlabeni jikelele kuye kwanda eminyakeni yamuva, ikakhulukazi e-United States, futhi kuhloswe ukuba kungabizi kakhulu.
Kulinganiselwa ukuthi abantu abadala e-United States bangase bavezwe ku-1 mg we-titanium dioxide ngekhilimu yesisindo somzimba ngosuku. Ngomuntu olinganisa, isibonelo, ama-150 lbs, okungaba ngu-68 mg wokuchayeka ngosuku.
Kodwa-ke, kuchazwe yi-World Health Organization (WHO) ngokuthi "isifo sobuthakathaka obuthakathaka" futhi "mhlawumbe i-carcinogenic kubantu" ngoba, ngokulinganisa okukhulu kakhulu, izifundo zibonise ukuthi zenze umdlavuza emagundini. Kubalulekile ukuqaphela ukuthi ukukhathazeka okuyinhloko kwesigaba se-WHO ukuvikela abasebenzi ezitshalweni lapho i-titanium dioxide yenziwa khona.
Abasebenzi bazokwehliswa ngemali ephakeme, mhlawumbe bayayithokozisa, ngesikhathi semisebenzi yabo.
Lezo zisebenzi zidinga ukuvikelwa emiphumeleni eyingozi, ikakhulu lapho isebenza nezinto ezifana ne-titanium dioxide ngezikhathi eziningana. Nokho, abukho ubufakazi bokuthi ukusetshenziswa kwe-titanium dioxide ngamanani amancane, njenge-cake frosting noma imithi, kubeka abantu engozini enkulu yomdlavuza.
Ucwaningo lwe-Titanium Dioxide ne-IBD
Ucwaningo olulodwa lwabheka kokubili imiphumela ye-titanium dioxide eyayinezinkoma ezixoshwa nge-colitis. Abacwaningi basebenzisa amakhemikhali emagundeni ukuze bakhule i-colitis, ekhomba ukuvuvukala emgqeni futhi akufani neze nokulonda kwe-ulcerative njengoba yaziwa kubantu. Ukwehlisa amagundane nge-colitis kuvame ukwenza kulezi zinhlobo zezifundo zokuqala, ukubona ukuthi kungaba yini isizathu sokuqhubekela phambili kwizifundo ezinkulu noma ukuqhubeka ucwaningo.
Okutholakala kulezi zinhlanzi kwakuwukuthi lapho benesifo sochungechunge futhi banikwe inani eliphakeme le-titanium dioxide nsuku zonke emanzini abo (noma ama-50 mg noma 500 mg kilogram ngayinye yesisindo somzimba), ubuchopho bubuhlungu. Amagundane ayengenayo i-colitis futhi eyanikezwa i-titanium dioxide ayengenayo izinguquko kumakholoni awo. Ngakho-ke, abacwaningi baphetha ngokuthi i-titanium dioxide ingase ibe yingozi kuphela uma sekukhona ukuvuvukala ekoloni.
Ucwaningo olufanayo lwaba nesakhi somuntu, futhi abantu abane-Crohn's disease kanye nesifo sokulonda kwesilonda bahlolisiswa. Lokho abacwaningi abathola ukuthi abantu abane-ulcerative colitis e- flare-up babenezibalo eziningi ze-titanium egazini labo. Abacwaningi baphetha ngokuthi ukuvuvukala ekoloni kwakusho ukuthi i-titanium engaphezulu yayithathwe lapho futhi yenze indlela yayo egazini. Ukuzicabangela lokhu, kanye nemiphumela yalokho okwenzeke kumagundane, abalobi besifundo bathi imiphumela yabo kufanele isenze sicabangele "ukusetshenziswa okuqapha kwalezi zinhlayiya."
Kube nezinye izilingo kubantu abanesifo sikaCrohn, esasifunda ukudla okungazange kube ne-nanoparticles. Isifundo sokuqala senziwa ezigulini ezingu-20 ezinezifo ezisebenzayo futhi zahamba izinyanga ezingu-4. Iziguli ezisezingeni eliphansi lokudla izinhlayiyana zazijwayele ukwenza kangcono kunezo ezingekho ekudleni. Isiphetho ukuthi ukusika izithasiselo zokudla nezinye izinto eziqukethe ama-microparticles noma ama-nanoparticles, kungenzeka ukuthi asize.
Okwesibili, isifundo esifanayo senziwa ngeziguli ezingu-83. Ukudla okufanayo kwakusetshenziselwa, kepha abacwaningi abazange bafinyelele esiphethweni esifanayo: iziguli ezidliwayo azizange zenze okungcono kunezo ezazingekho ekudleni. Lokhu kusho ukuthi akukho bufakazi obuhle bokuthi ukusika izinto ezifana nezithasiselo zokudla kunomthelela wesifo sikaCrohn. Kuyinto 'yokubuyela ebhodini lokudweba' kubacwaningi.
Ukuvuselela i-Sigma ehambisana nokudla
Kubantu abane-IBD, kunenhlamba ehambisana nokudla. Abangane, umndeni, kanye nozakwethu bangase babheke ukubuza lokho umuntu one-IBD adla futhi enze izahlulelo mayelana nokudla kokusebenza kunempawu . Abantu abane-IBD bavame ukwazi ukuthi yini ukudla okuvame ukuba yinkinga kakhulu futhi kwezinye izimo, kungenzeka kube nokudla okukhawulelwe okwesikhashana. Labo abaye bahlinzwa emathunjini abo ukuphatha i-IBD yabo futhi abajwayele ukuthuthukisa ukuvinjelwa kungadinga ukugwema ukudla okuthile noma amaqembu okudla ngokuphelele.
Ucwaningo alubonwanga, noma kunjalo, ukuthi ukudla kubangelwa noma kubangela i-IBD. Iziguli zikhuthazwa ukuba zidle njengokudla okunempilo ngangokunokwenzeka, okufaka izithelo nemifino. Ukusebenza nomhlengikazi onokuhlangenwe nakho ekwelapheni abantu abane-IBD kuyasiza ukuze udle ukudla okungeyona nje kuphela enobungane ku-IBD kodwa futhi kuqukethe amavithamini namaminerali abanezidingo ze-IBD . Ngesikhathi sokuphazamiseka, abantu abaningi abane-IBD banciphisa ukudla, okwamanje ama-calories ayadingeka ngalesi sikhathi, hhayi okuncane.
Izwi elivela
Lapho izifundo mayelana ne-IBD ziphuma ukuthi inselele lokho esikuqonda njengamanje ukuthi kuyiqiniso, ingashukumisa ukwamukela kwethu konke okuhlobene nalezi zifo. Lokhu kuyiqiniso ikakhulukazi ngokucwaninga ngokudla, futhi abezindaba-abangeke babe nokuqonda okujulile kwe-IBD-bathambekele ekubambeni kubo. Ucwaningo mayelana ne-titanium dioxide alukakabonakali ukuthi kufanele noma akufanele sikhathazeke ngalesi sengezo sokudla. Ukudla okunamnandi nokudla okuncane okucutshungulwa ngokuvamile kungumqondo omuhle. Ngaphambi kokusika ukudla ngokuphelele, noma kunjalo, umqondo omuhle ukukhuluma nodokotela wakho we-gastroenterologist kanye / noma isazi sezilwane mayelana nezinketho eziphephile, ezinomsoco, futhi ezisebenzayo.
> Imithombo:
> I-IARC Ukusebenza Iqembu Ekuhlolisweni Kweengozi Ze-Carcinogenic kubantu. "I-carbon emnyama, i-titanium dioxide, ne-talc. I-IARC i-monographs ekuhloleni izingozi ze-carcinogen kubantu." I-World Health Organization, i-International Agency for Research on Cancer, Vol 93, 2010.
> Lomer MC, Grainger SL, Ede R, et al. "Ukungabi nokusebenza kokunciphisa ukudla kwe-microparticle ekuhlolweni okugxilwe kwamaningi kweziguli ezine-Crohn's disease esebenzayo." I-Eur J Gastroenterol Hepatol. 2005; 17: 377-384.
> Lomer MC, uHarvey RS, u-Evans SM, et al. "Ukusebenza nokubekezelelana kokudla okuncane okuyi-microparticle ku-double blind blind, randomized, pilot study in the Crohn's disease." Eur J Gastroenterol Hepatol 2001; 13: 101-106.
> Ruiz PA, uMorón B, u-Becker HM, et al. "I-Titanium dioxide nanoparticles ivusa ukwanda kwe-DSS-induced-colitis: indima ye-NLRP3 inflammasome." Umhlaka 2017 Jul; 66: 1216-1224.
> Weir A, Westerhoff P, Fabricius L, Hristovski K, von Goetz N. "Titanium dioxide nanoparticles ekudleni nemikhiqizo yokunakekelwa komuntu siqu." NgokweSci Technol 2012. Feb 21; 46: 2242-2250.