Akuyona impendulo ye-slam dunk, kodwa ochwepheshe abaningi bancike ku-NSAID
Uma ukhuthazelela izinhlungu zekhanda ngezikhathi ezithile, ungase uzibuze ukuthi yiliphi ibhodlela lepilisi elizolifinyelela etafuleni lakho ledeskithophu noma ekhomishini yezokwelapha ekuqaleni kokuhlaselwa.
Ngamanye amazwi, kufanele ufinyelele ibhodlela le-Tylenol (acetaminophen) noma ibhodlela le-Advil noma le-Motrin (ibuprofen)? Ingabe enye iyasebenza nakakhulu kunomunye?
Ake siphenye lo mbuzo ngokuqhubekayo.
Ukwelashwa Kwezintambo-Thayipha Izinhliziyo
Ngokujwayelekile, abantu abanezinkinga zokukhanda ngamathumbu baphatha imishanguzo engaphezu kwemithi kanye neminye imithi engeyona yezokwelapha njengokulala, ukuzivocavoca, amanzi, ne-caffeine.
Abantu bavame ukuya emtholampilo kadokotela uma kuphela ikhanda labo lingavumelani nalezi zindlela zokwelapha, noma uma bezwa ezinye izimpawu ngaphezu kwamakhanda abo, njengokushintshwa okubukwayo kusuka e- aura- empeleni kubonisa ukuxilongwa kwe- migraine hhayi ubuhlungu bekhanda .
Izibonelo zakudala zemithi ephezulu kakhulu ye-counter-the-counter yilezi:
- I-Tylenol (i-acetaminophen)
- Ama-anti-inflammatories, noma i- NSAID njenge-Aleve (i-Naproxen Sodium), i-Motrin / Advil (Ibuprofen)
Okushiwo Ucwaningo Ngo-Ibuprofen ngokumelene noTylenol
Ngabe ibhodlela lithathaphi ikhabhinethi yezokwelapha noma ideskithodi? Yebo, cishe kungenzeka ukuthi isebenze, nakuba ibuprofen ingaba ngempumelelo kakhulu.
Esifundweni esidala, ku- Journal of Clinical Pharmacology , abantu abangaphezu kuka-450 abanezinkinga zokukhanda ikhanda babengenakulinganiswa ukuthola i-ibuprofen engama 400mg, 1000mg we-Tylenol, noma i-placebo. Imiphumela yabonisa ukuthi kokubili ibuprofen noTylenol babephumelela kakhulu kune-placebo ekunciphiseni ikhanda, futhi ibuprofen itholakala ukuthi iphumelela kakhulu kune-acetaminophen.
Lokho kuthiwa, ezinye izifundo azitholanga umehluko phakathi kukaTylenol ne-NSAID ekunciphiseni ubuhlungu bekhanda lokuhlukunyezwa kwekhanda.
Isibonelo, isifundo sokubuyekeza ku- Pain sitholile kokubili i-Tylenol (umthamo we-1000mg) ne-ibuprofen (i-400mg dose) ukuthi ibe ngcono kune-placebo ekunciphiseni ngokulinganisela ukuya ezinhlokweni ezinzima zobuhlungu bezinkinga (usebenzisa ipharamitha yezinhlungu ezimbili emva kokuthatha imithi) .
Akutholakalanga ukuthi iphumelele kakhulu kunomunye.
Ucwaningo lubuye lathola ukuthi inani labantu abadinga ukuthatha iTylenol noma ibubuprofen ukuthola ukukhululeka kwekhanda emahoreni amabili cishe cishe ayisishiyagalolunye kokubili. Lokhu kungcono kakhulu futhi kusho ukuthi kusenabantu abaningi abangatholi ukukhululeka okufanele-okuncane komzwelo wokungaxhunyiwe.
Impendulo: Ibuprofen Versus Tylenol
Ngakho impendulo yukuthi iTylenol noma i- NSAID iyindlela ekhethekileyo yokuqala yokukhetha ukunciphisa ikhanda lakho lekhanda lokukhathazeka. Ngokomthamo, i-ibuprofen ingu-200 noma 400mg isilinganiso esivamile. Uma uthatha i-naproxen sodium (i-Aleve), umthamo owodwa ojwayelekile ungama-220 noma u-550mg.
Khumbula-ke ukuthi ama-NSAID anemiphumela eminingana engalungile futhi kufanele agwenywe ngabanye abantu, ikakhulukazi labo abanomlando wesisu lokuphuma kwegazi, isifo sezinso, kanye nesifo senhliziyo. Abantu abanomlando we-asthma kufanele futhi baqaphe ngokuthatha ama-NSAID.
Ngaphezu kwalokho, uma ukhulelwe, i-acetaminophen ngokuvamile ikhetha ukhetho lwekhanda lokuhlukunyezwa, nakuba uqiniseke ukuthi uqinisekisa nesibhedlela sakho. Ngokuvamile, kubalulekile ukuthi uhlale ukhuluma nomhlinzeki wakho wezempilo ngaphambi kokuba uthathe noma yimiphi imithi, kuhlanganise nalabo abangaphezu kwe-counter, ukuqinisekisa ukuthi iphephile kuwe.
Okokugcina, uma unezinkinga zezinkinga ezivamile noma ezingapheli, akusihle ukuthatha njalo ama-analgesics ukulawula ubuhlungu. Lokhu kungaba empeleni ukubuyisela emuva futhi kubangele ukukhanda ikhanda , okungaba nzima ukuhlukanisa izinkinga zokuhlukunyezwa okuvamile-ukukhuluma okubili.
Lapho iTylenol noma i-Ibuprofen ihluleka
Uma ungatholi ukukhululeka kwekhanda kumthamo we-Tylenol noma i-NSAID, ukukhetha okulandelayo kuzoba ukucubungula umthamo we-tablet we-caffeine ohlangene nokukhulula ubuhlungu, njenge-Excedrin Extra Strength (equkethe i-acetaminophen 250mg, i-aspirin 250mg , ne-caffeine 65mg).
Eqinisweni, ukuqala nge-analgesic kanye ne-caffeine inhlanganisela kungase kube ngcono ekunciphiseni i-headache-type headache-type elula kune-analgesic (njenge-Tylenol noma ibuprofen). Lokho kusho ukuthi ungase ube nemiphumela emibi kakhulu, njengokungathi ukhathazekile ngesisu noma isizungu (nakuba, ngokuvamile kubumnene futhi kuphila isikhathi esifushane).
Izwi elivela
Ekugcineni, uma unezinkinga zezinhlungu ze-episodic futhi ufuna ukuthatha imithi yoku-over-the-counter, ibuprofen noma i-Tylenol kuyisinqumo esinengqondo. Ungathola inzuzo eyengeziwe ku-ibuprofen, kodwa lokhu akuwona umthetho onzima futhi okusheshayo. Njengoba njalo, khuluma nodokotela wakho ngaphambi kokuba uthathe noma yimiphi imithi.
> Imithombo:
> Diener HC. Inhloko: ukuqonda, ukuqonda, ukwelashwa nokuphathwa kweziguli. I-Int J Clin Pract Suppl. 2013 Jan; (178): 33-6.
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> Lipton RB, Diener HC, Robbins MS, Garas SY, Patel K. Caffeine ekulawuleni iziguli ezinezinwele. I-J Headache Pain. 2017; 18 (1): 107.
> Moore RA, Derry S, Wiffen PJ, Straube S, Bendtsen L. Ubufakazi bokusebenza kahle kokwelashwa okunzima kwe-episodic-type headache-type headache: ukuhlaziya indlela yokwelashwa okungahleliwe ukuze uthole ukwelashwa ngomlomo. Ubuhlungu . 2014 Nov; 155 (11): 2220-8.
> Taylor FR. (2017). Inhlobonhlobo yezintambo ezinhlobonhlobo kubantu abadala: Ukwelashwa okunamandla. U-Swanson JW, u-ed. Kusesikhathini. Waltham, MA: UpToDate Inc.