Ucwaningo lwamuva luveze ukuthi izidakamizwa ze-statin zingandisa kakhulu ingozi yokuthuthukisa izidakamizwa . Abacwaningi eSoot Antonio Military Medical Centre eTexas baqhube isifundo esasihlanganisa ama-6972 amabili wabasebenzisi base-statin nabasebenzisi abangewona abakwa-statin. Bathola ukuthi ukuthuthukiswa kwe-cataract kwakungu-27% ngaphezulu kwabasebenzisi basebenzi. Abacwaningi bakhombise ukuthi ukutadisha akuphelelanga futhi akukho ndlela ekhombisa ubudlelwane obangela imbangela.
Kodwa-ke, abacwaningi bathi ukusetshenziswa kwe-statin kubonakala sengathi kuhloswe ingozi yokuthuthukisa i-cataract.
I-statin izidakamizwa zenza kanjani ukubola?
Kuyaziwa ukuthi ukulimala okwenziwe nge-oxidative kunomthwalo owodwa ekuthuthukiseni i-cataracts. Izitatimende zinomthelela owenziwe nge-bidirectional ngezinqubo ze-oxidative ezingase zenze ingozi ye-cataract ikhule. Ezinye izifundo ziye zathintela ukuthi i-cholesterol ephakeme idinga ngaphakathi kwamaseli akhula ngaphakathi kwe-lens futhi kuyadingeka ukuze kugcinwe ukukhanya. Ngenxa yalokho, ama-statins angavimbela le nqubo eyenza i-cataract ithuthuke. Kuye kwaphawulwa ukuthi abantu nezilwane ezinesifo se-cholesterol eyinzalo banomngcipheko okhulayo wokuba ne-cataracts.
Ucwaningo oluningi luyafaneleka. Nakuba izifundo eziningi ezibandakanya ukusetshenziswa kwe-statin kanye ne-cataracts ziqaphele ukuhlunga izici eziyinkimbinkimbi ezingathonya isifundo, izici ezifana nesifo sikashukela zingase zifake imiphumela.
Iziguli eziningi zesifo sikashukela nazo zinezifo zenhliziyo futhi zithatha imithi yesimiso. Iziguli zesifo sikashukela zivele zengozi yokuthuthukisa izifo ezingapheli nezingaphezu kakhudlwana kunabantu abangenaso isifo sikashukela. Ukucindezela isithombe nakakhulu, sekukhona izifundo ezithile esikhathini esedlule ezibonisa ukuthi izitembu zinganciphisa ukuthuthukiswa kwezidakamizwa.
Yiziphi Izidakamizwa Ze-Statin?
I-statin yisigaba semithi esetshenziswa ikakhulukazi ekunciphiseni amazinga e-cholesterol emzimbeni. Izidakamizwa ze-Statin zisebenza ngokuvimbela isenzo samakhemikhali atholakala esibindi esenza i-cholesterol. Sonke sidinga izinga elithile le-cholesterol emizimbeni yethu. I-cholesterol iyadingeka ukuze amaseli ethu asebenze kahle. Noma kunjalo, amazinga angavamile we-cholesterol angabangela ukutholakala kwe-atherosclerosis. Ukwehla kwesifo sofuba kubangelwa yi-cholesterol plaques eyakha emithanjeni yethu yegazi futhi ivimbele ukugeleza kwegazi okujwayelekile. I-statin inganciphisa i-cholesterol ebeka phansi ingozi yokuhlasela kwenhliziyo nokushaywa yisifo. Izibonelo zama-statins yiLimpitor, Pravachol, Crestor, Zocor, Lescol noVytorin.
Iyini i-Cataracts?
I-cataract i-clouding ye- lens yeso . I-cataract yiyona imbangela ehamba phambili yobumpumputhe phakathi kwabantu asebekhulile kunama-55. Iningi labantu asebekhulile banezinga elithile le-lens clouding, okuyingxenye evamile yokuguga. I-lens itholakala ngemuva kwe-iris. Inesibopho sokugxila ekukhanyeni kwe-retina, nokukhiqiza izithombe ezicacile, ezibukhali. I-lens inamandla okuguqula isimo, eyaziwa ngokuthi indawo yokuhlala. Njengoba i-eye iso, noma kunjalo, i-lens inzima futhi ilahlekelwe ikhono layo lokuhlala. Amaseli afile noma amangqamuzana ashintshwe ngamakhemikhali aqoqa lens, okwenza i-lensi ibe kancane.
Ukukhanya okuvame ukuba kugxilwe yi-lens kuhlakazeke nxazonke ngenxa ye-Cloudiness, ngakho umbono awusekho ocacile futhi obukhali.
Ama-cataracts ngokuvamile awabuhlungu. Ngokuvamile baqala njengendawo encane, opaque bese bekhula kancane kancane. Umbono awuvame ukuthintwa kuze kube yilapho indawo enkulu yelensi iphenduka. Izimpawu ezilandelayo zingenzeka nge-cataracts:
- Umbono ophundlekile
- Ukuzwela okukhanya
- I-Halos izibani eziseduze
- Umbono wobusuku obunzima
- Ukuphuka noma ukuqubuka kombala wombala
- Umbono kabili
- Izinguquko emehlo zigqoka izidakamizwa
Okufanele Ukwazi
Kubalulekile ukuveza ukuthi kungase kungabi ukuhlakanipha ukuyeka ukuthatha imithi yakho ye-cholesterol ngoba nje ukwandisa ingozi yezinkinga zengozi.
Ukwelashwa kwe-Cataract ngokuvamile kuyinkambiso ephumelelayo kakhulu, futhi inakekelwa kahle, kuyilapho i-cholesterol ephakeme ingandisa kakhulu ingozi yokuhlasela kwenhliziyo, ukushaya isifo nokufa. Udokotela wakho kufanele akhulume nawe ukuthi ukuthatha izitembu kukhonjiswe kwezinye izifundo ukuze ukwandise ingozi yokuthuthukisa i-cataracts.
> Imithombo:
> Leuschen, uJessica ND. Uhlobo lwe-Statin Lokusetshenziswa Nge-Cataracts: I-Propensity Score-Ukulinganisa Okufanisiwe. I-JAMA Ophthalmology, 2013.