Imithi ye-Antispasmodic yokuqothulwa-i-IBS ebaluleke kakhulu
I-bentyl (i-dicyclomine) imithi yokwelashwa kwesifo sofuba esiswini (IBS). I-bentyl ibhalwe ngokuthi imithi ye-antispasmodic futhi ngakho-ke kucatshangwa ukuthi iyasiza ekunciphiseni ukuphazamiseka kwamathumbu emathunjini angabangela ubuhlungu besisu kanye nezinkinga ze-motility ezikhomba izimpawu ze-IBS. Kodwa-ke, ngenxa yobungozi bokuqothulwa, i-Bentyl kungenzeka ukuthi ingalungile kubantu abanokuqothulwa-IBS (IBS-C) enkulu kakhulu.
Futhi ngenxa yephrofayela yayo yethinta, i-Bentyl ayisekho njalo.
I-Bentyl ihlukaniswa njengemithi elwa ne- anticholinergic ngoba iyanciphisa umphumela we- neurotransmitter acetylcholine ngaphakathi komzimba. Isenzo esinciphile se-acetylcholine siphumelela ekunciphiseni kwe-muscle spasms nokucinwa kwe- mucus . Ngeshwa, ngaphezu kokuletha impumuzo ye-IBS, umphumela we-Bentyl esenzweni se-acetylcholine nawo ungaletha wonke umphumela wemiphumela emibi engafuneki.
Imiphumela emibi yezinkulungwane eziningi
Umphumela we-anticholinergic we-Bentyl ungathinta izinhlelo kuwo wonke umzimba. Imiphumela emibi kakhulu ebikiwe ihlanganisa:
- Umbono ophundlekile
- Ukuqokwa
- Yehlisa ukujuluka
- Ukunciphisa ukuchama
- Isizungu
- Umlomo omile
Ezinye imiphumela emibi ingase ihlanganise ukulahlekelwa ukudla, ukugubha, ukukhanda ikhanda, ukulala noma ubuthakathaka.
I-Bentyl ingabangela nemiphumela emibi kakhulu, njengokudideka noma ukuwa. Kungabangela imizwa engalungile kanye nokubona okubonakalayo noma okuzwakalayo, kanye nemiphumela emibi yesikhumba efana nemifantu noma i-itching.
Uma uhlangabezana nanoma yikuphi okungavamile noma okuphathelene nemiphumela emibi, xhumana nodokotela wakho. Uma uhlangabezana nanoma yimiphi imiphumela emibi, funa ukwelashwa ngokushesha.
Abantu asebekhulile bayacwayiswa ukuthi amaBentyl angase angafaneleki kubo.
Ingabe Iphumelele Kangcono?
Nakuba i-Bentyl imishanguzo ejwayelekile ye-IBS, kunesidingo esikhulu sokucwaninga mayelana nokusebenza kwayo.
Ukuhlolwa kocwaningo, kuhlanganise ne-American College of Gastroenterology ngo-2014, kutholwe isifundo esisodwa semitholampilo esihlolisise ukusebenza kweBentyl ekunciphiseni izimpawu . Lolu cwaningo lwaluqala ngo-1981, lubonisa ukuthi kuncane kangakanani ucwaningo olwenziwa ekuqinisekiseni ukuthi lesi sidakamizwa siphumelele yini. Imiphumela yabonisa ukuthi i-Bentyl yayiphakeme kune- placebo ekunciphiseni ubuhlungu besisu nangesisa, nokuthuthukisa ukusebenza kwezimpawu kanye nezimpawu ze-IBS jikelele. Ukukhathazeka ukuthi cishe amaphesenti angu-68 alaba bantu ahlangabezana nemiphumela emibi ye-anticholinergic.
Ukubuyekezwa kuka-2014 kuphawulwe ukuthi ngama-antispasmodics, i-peppermint oil ifunde kahle futhi ithola ukuthi isebenza kahle futhi ibekezelela kahle imiphumela embalwa emibi. Nokho, ngokungafani ne-Bentyl, ayilawulwa yi-FDA njengoba ithengiswa njengesengezo.
Indlela Yokuthatha Abaningi
Eziningi ziza ngezindlela eziningi-njenge-capsule, tablet noma isiraphu. Kuhlale kuthathwa ngomlomo. Qinisekisa ukuthi ulandela imiyalelo kadokotela wakho ngokucophelela ngokuthi ungayithatha nini. Udokotela wakho angakuqala esenzweni esincane futhi kancane kancane ukwandise umthamo wakho.
Ngokuvamile, i-Bentyl kufanele ithathwe izikhathi eziningana phakathi nosuku ngezikhathi ezihlukene. Udokotela wakho angancoma ukuthi uthathe amaminithi angama-30 kuya kwangu-60 ngaphambi kokudla.
> Imithombo:
> Dicyclomine. I-MedlinePlus. https://medlineplus.gov/druginfo/meds/a684007.html.
> Ford A, et.al. I-American College ye-Gastroenterology Monograph ekuphathweni kwe-Irritable Bowel Syndrome ne-Chronic Idiopathic Constipation . I-American Journal of Gastroenterology 2014 109: S2-S26.
> Ikhasi J, Dirnberger G. "Ukwelashwa kwesifo sofuba esilusizi ngeBentyl (dicyclomine hydrochloride). Journal of Clinical Gastroenterology 1981 3: 153-156.
> Trinkley K, Nahata M. Imithi Yokuphathwa Kwe-Irritable Bowel Syndrome. Ukugonywa ngo- 2014 89: 253-267.