Izidakamizwa Ezasetshenziselwa Ukwelapha I-Chemotherapy-I-Anemia Ekhulelwe
Ngenkathi uphethwe i- chemotherapy , uzobe uhlolwe futhi uhlolwe nganoma yiziphi izinkinga. Isivivinyo esisodwa esivamile yi-Complete Blood Count (CBC), esinika udokotela wakho ulwazi olubalulekile mayelana nezinhlobo namanani amangqamuzana egazini lakho. Uma ukuhlola kwakho kwe- CBC kubonisa ukuthi inani lakho elibomvu seligcini legazi liphansi, ungase ube ne- anemic .
I-Link Between Cancer Breast, Chemotherapy, ne-Anemia
I-anemia ingenza ukulwa nomdlavuza webele kunzima nakakhulu kuwe; ungase uzizwe ubuthakathaka, udangele, udizizi noma udinwe.
Ungase ukulimaze kalula noma ube nezindwangu ze-noseble. I-anemia ingenza buthakathaka umzimba wakho kanye nesimiso somzimba sokuzivikela, okwenza kube nzima ngomzimba wakho ukulwa nezifo nokutheleleka.
Uma udokotela wakho ethola ukuthi une-anemia ngenxa ye-chemotherapy, angakunikeza imithi ukukusiza ukuthi ukhiqize amanye amangqamuzana egazi abomvu. I-Aranesp (i-darbepoetin alfa) ne-Propress (i-epoetin alfa) yizidakamizwa ezimbili ezivame ukusetshenziswa kule njongo. Ukukhululwa noma ngomjovo noma ngokusebenzisa ukumnika okufakwe ngaphakathi (IV), bangakwazi ukukhulisa ukukhiqizwa kwegazi elibomvu futhi kungakusiza ukuba ugweme ukudinga ukumpontshelwa igazi.
Yeka ukuthi lezi zidakamizwa zisebenza kanjani njengeziphuthumayo ze-Red Blood Cell
Igazi lenziwe emnothweni wakho, izicubu ezithambile, ezipanjiwe ezingxenyeni zamathambo akho. Amangqamuzana omnyoba ama-cell amangqamuzana ahlukanisa ngokushesha, aphethwe yi-chemotherapy. Amaseli omnyo omnyo ambalwa asho ambalwa amangqamuzana egazi. I-CBC yakho ingabonisa ukuthi inani lakho legazi elibomvu liphansi, futhi une-anemic.
Ngokuvamile, izinso zakho ziveza i-erythropoietin, iphrotheni ekhuthaza ukukhiqizwa kwamaseli abomvu egazi.
Kodwa ngesikhathi se-chemo ngomdlavuza webele, izinso zakho kungenzeka zingenzi i-erythropoietin eyanele. Ukunyatheliswa kanye ne-Aranesp yizinto ezifakwe ngabantu ezenziwe nge-erythropoietin, kanti umthamo ofanele lo muthi uzokuthuthukisa ukukhiqizwa kwamaseli akho abomvu egazi.
Imiphumela emibi yokubhalisa
Ukunyatheliswa yisidakamizwa esiphephile kakhulu, futhi iziguli eziningi azizwa nemiphumela emibi. Ezinye iziguli zingase zihlakulele umkhuhlane. Unethuba elingaphansi kwezingu-22% lokuba nalezi zenzo:
- Uhudo
- I-nausea
- Ukuvota
- Ukugcinwa kwe-Fluid (i-edema)
- Ukukhathala
Shayela Udokotela Wakho Uma Unayo Lezi Izimpawu:
- Ukusabela okweqile (izimpande, ukuphefumula kwezinkinga, ukuvuvukala kobuso, izindebe, ulimi noma umphimbo)
- Ubuhlungu besifuba
- Ukuphelelwa umoya
- Ukuzizwa ngokungazelelwe kokungabi namandla noma ubuthakathaka (ikakhulukazi obuthakathaka)
- Ubuhlungu noma ukuvuvukala emilenzeni yakho, izinyawo, noma ama-ankles
- Umfutho wegazi ophezulu
- Ukukhanya okukhanyayo (ukuzonda, ukuphelelwa amandla)
Imiphumela emibi ye-Aranesp
U-Aranesp unemiphumela emibi kakhulu, ngakho-ke qiniseka ukuthi uxoxa ngezingozi ezingenzeka ngodokotela wakho. Uzosebenza nawe ukucacisa umthamo ophansi kunazo zonke ukulawula isibalo sakho se-cell ngenkathi ulawula izingozi ezingenzeka. Kuziguli ezine nomdlavuza wesifuba, lesi sifo singakhula ngokushesha futhi kukhona amathuba okufa ngokushesha uma uthatha i-Aranesp.
Kungabangela izinkinga ezinzulu zenhliziyo, kuhlanganise nokuhlaselwa kwenhliziyo, ukuhluleka kwenhliziyo, nokushaywa yisifo. Ama-clots egazi abuye abikwe ngenkathi ephathwa ngophahla ne-Aranesp. Shayela umhlinzeki wakho wezempilo ngokushesha uma unayo yalezi zimpawu:
- Ubuhlungu besifuba
- Ukuphefumula noma ukuphefumula
- Ubuhlungu noma ukuvuvukala emilenzeni yakho
- Ingalo noma imilenze epholile noma emlenze
- Ukudideka okungazelelwe, ukukhathazeka ukukhuluma noma ubunzima ukuqonda abanye
- Ubuthakathaka ebusweni bakho, izingalo, imilenze noma ohlangothini olulodwa lomzimba wakho
- Ukukhathazeka okungazelelwe
- Inkathazo engazelelwe
- Ukulahlekelwa kokwazi
I-Aranesp ineminye imiphumela emibi kakhulu, kuhlanganise nokucindezelwa kwegazi eliphezulu, ukugubha, ukulwa namagciwane ku-Aranesp, okusho ukuthi umzimba wakho ungavimbela i-Aranesp futhi ukhulise i-anemia nokuphendula okukhulu kwe-allergenic.
Izincomo Ngesikhathi Ukwelashwa
Ngaphambi kwe-Aranesp yakho yokuqala noma ukwelashwa okubhalisiwe, udokotela wakho uzoyala i- CBC ukuthola amazinga amangqamuzana akho abomvu egazi, i- hemoglobin , i- hematocrit , neyensimbi.
Njengoba ukwelashwa kuqhubekela phambili, uzoba nokuhlolwa okuningi kwegazi ukuhlola ukusebenza komuthi futhi uqiniseke ukuthi uthola isilinganiso esifanele.
Ngaphambi kokuqala noma yikuphi ukwelashwa, khuluma nodokotela wakho mayelana nesidingo sakho kanye nezingozi ezingase zibe khona kanye nemiphumela emibi.
Imithombo:
UkuPhatha nokuPhathwa kwezidakamizwa. "I-Aranesp Ukuchaza Ulwazi." Kubuyekeziwe ngo-2015.
UkuPhatha nokuPhathwa kwezidakamizwa. "Ukubhalisa Ukuchaza Ulwazi," kubuyekezwe 2013.
"I-Araspen Labeling Review." I-FDA Postmarket Ulwazi Lokuphepha Kwezidakamizwa Kwabagulako Nodokotela, ngo-2013.
Muller, R., Baribeault, D. "Izilinganiso ezithengisiwe-izikhathi zamaphesenti ama-erythropoietic agents e-anemia ekhishwa ngamakhemikhali". I-American Journal of Health-System Pharmacy , 2007, 2547-2556.