Indlela yokuvuselela ubuchopho ithatha isithembiso sokuphatha izici ze-autism
Umcwaningi uthi "Uthole i-Pathology of Autism"
UDkt. Manuel Casanova ubamba isihlalo esiphezulu eNyuvesi yaseKentucky. Wabhalwa amaphepha amaningi okubuyekezwa kontanga, futhi uthola izimali ezivela eNational Institutes of Health. UDkt. Casanova uqhuba ucwaningo ngobuchopho be-autistic - futhi, ngokusho kwakhe: "Ngicabanga ukuthi sithole ukukhubazeka kwe-autism.
... Ichaza okuningi, konke kuyaqondakala. "
UDkt. Casanova akakholelwa nje ukuthi uthola ukukhubazeka kwe-autism, kodwa futhi usebenza ekwelapheni okungenzeka kube namandla okunciphisa izimpawu ze-autistic ze-hypersensitivity ngaphandle kokuyekethisa ubuciko kanye namakhono afanele okwenza abantu base-autistic bavelele ngendlela engavamile.
Ama-Minicolum ku-Autistic Brain: Izindaba Ezinhle Nezindaba Ezimbi
Ingxenye yangaphandle yobuchopho ibizwa ngokuthi i-neocortex. Phakathi kwe-neocortex kukhona amaqembu amangqamuzana okuthiwa ama-minicolumns. Lezi zingu-minicolumns iyunithi encane kunazo zonke yamaseli akwazi ukucubungula ulwazi. Ngokuvamile, amaminithi amancane ahlanganisa amangqamuzana amancane, okuthiwa ama-neurons, avumela ukukhulumisana hhayi kuphela ngaphakathi kweminicolumn eyodwa kodwa futhi phakathi kwezinhlangothi ezahlukene zobuchopho.
Ama-minicolns kubantu abane-autism bancane futhi baningi kunokuvamile. Ngaphezu kwalokho, i-neurons ngaphakathi kweminithi ngayinye iyancishiswa ngosayizi.
Lokhu kungaba kokubili okuhle nokubi, kusho i-Casanova: "Njengoba ukusebenza kahle kwama-neurons kuyisisindo sesayizi yamaseli, ukutholakala kwama-neurons amancane ebuchosheni beziguli ze-autistic kunomthelela omkhulu endleleni izingxenye ezahlukene zobuchopho sebenzisana nomunye nomunye. Imisebenzi yobuchopho edinga ukuhlolwa okude (isib. ulimi) lungase lukhubazeke kuyilapho lezo ezincike ekuxhumaneni okufishane (isib. ukuphathwa kwemathematika) kungagcinwa noma kuqiniswe. "
Ngamanye amazwi, abantu abane-autism bahle kakhulu kunoma yini engacubungulwa endaweni eyodwa yobuchopho - njengokucwaswa kwezibalo nokubukwa. Kodwa-ke, kukhona okubi kakhulu kunoma yini edinga ukusebenzisana phakathi kwezinhlangothi ezihlukahlukene zobuchopho - njengamakhono omphakathi , ulimi, nokubhekwa komuntu.
Ukungena Okubi Phakathi KwaMinicolumns Kungase Kubangele Izinkinga Ezisemqoka
Ngokusho kweCasanova, umphumela owodwa ohlangothini lwama-minicolum angeziwe ngamaseli athile amancane "ama-stimuli awasekho ngaphakathi kwamaminithi amancane, kodwa kunalokho aphuluke emigodini yamaminithi eseduzane ngaleyo ndlela anikeze umphumela we-amplifier. Lokhu kungachaza ukucindezeleka kweziguli ezithile ze-autistic kanye ukuhlukunyezwa. "
I-Casanova ifanisa lokhu namanzi aqukethe eshaweni. "Izindwangu ezivimbelayo zisebenza ngendlela efanelana nesendwangu sokugeza. Uma usebenza ngokufanele futhi uguqula ngokugcwele ibhawende isendwangu sokugeza igimbela amanzi ekuchitheni phansi." Abantu abane-autism banezindwangu zokugeza ezivulekile.
Ukwandisa Ukwandiswa Kwangathi Kungase Kufundwe Izinkinga Nezimpendulo Ezingaqondakali Ngaphandle Kokunciphisa Ukudala
UDkt. Casanova ukholelwa ukuthi kungenzeka ukwandisa "ukugxila" okuzungezile amaminithi amancane, ngaleyo ndlela ukunciphisa ukucindezeleka okuzwakalayo kanye namathuba okubamba.
Ubuhle bemfundiso yakhe yilezi, imiphumela emibi ingabhekiswa ngaphandle kokuthinta ikhono labantu abane-autism ukucabanga, ukuqonda nokudala ngaphandle kwebhokisi.
Nakhu ukuthi kusebenza kanjani: Ngokusho kwe-Casanova, "impahla eyinhloko yalezi [amaminithi amancane] nokuhlola ukuthi ama-degree angama-90 kuya phezulu kwe-cortex." Yilawo kuphela amaseli enza kanjalo. " I-Casanova ichaza ukuthi ukugqugquzelwa kwamandla kagesi (TMS) kungahle "ifinyelele insimu yamagnetic ku-cortex," ngaleyo ndlela igcizelela ukugxilwa okuzungeze amaminithi amancane. Lokhu ukwelashwa kungaba (ngokusho kocwaningo olukhona) kube nemiphumela emibi kakhulu.
Okubaluleke kakhulu, ngeke kube nomthelela ohlangothini wokuguqula ubuntu noma izinqubo zokucabanga zomuntu ophathwayo.
Ingabe i-TMS ingaba yi "Isenzo sangempela?"
Lo mbono awuyinto engavamile njengoba kungase kuzwakale. Eqinisweni, i-TMS isivele ibonakale iwusizo ekwelapheni izifo zengqondo ezifana nesifo schizophrenia nokucindezeleka. Izivivinyo zemitholampilo ziyaqhubeka ngokusebenzisa i-NIH ukuhlola ukusetjenziswa kwe-TMS ekwelapheni amazwi ahlosiweko. Phakathi neminyaka eminingana, izinhlangano ezihlukahlukene zenze izilingo ze-TMS - kodwa kuze kube manje akukho ukuvumelana mayelana nemiphumela. Nakuba izivivinyo eHarvard nakwezinye izindawo kubonakala sengathi zinezithembiso, futhi izihloko ezisezincwadini ezifana ne-Newsweek zinezindlela ezinhle, i-TMS ihlala yindlela yokwelapha engakakulungeli ukusetshenziswa jikelele.
Izinkomba:
Ingxoxo yocingo noDkt. Manuel Casanova. September, 2006.
I-Casanova MF, i-Kooten IAJ van, i-Switala AE, i-Engeland H van, u-Heinsen H, i-Steinbusch HWM, i-Hof PR, i-Schmitz C. Ukungahleleki kwe-cortical minicolumnar inhlangano ye-prefrontal lobes yeziguli ze-autistic. Ucwaningo lwezokwelapha lwe-Neuroscience 2006; 6 (3-4), 127-133.
Casanova MF, Kooten IAJ van, Switala AE, Engeland H van, Heinsen H, Steinbusch HWM, Hof PR, Trippe J, Stone J, Schmitz C. Okuncane okungekho emthethweni ku-autism. I-Acta Neuropathologica 2006; 112 (3), 287-303.
I-Casanova MF, Ukungahleleki Kwezingxenye ZamaCortical In The Brains Of Autistic Individuals. Kuthulwe kwi-All Wales Autism Resource (AWARES) International Conference, 2006.
Chae, JH, Nahas, Z., Wassermann, E., Li, X., Sethuraman, G., Gilbert, D., et al. (2004). Ucwaningo lokuphepha lomshayeli we-stimulant magnetic stimulation (rTMS) ephindaphinda e-Tourette's syndrome. I-Neurology Engqondweni Neziciko, 17 (2), 109-117.
Mantovani, A., Lisanby, SH, Pieraccini, F., Ulivelli, M., Castrogiovanni, P., & Rossi, S. (2006). Ukuvuselela ukuvuselela kwe-magnetic (rTMS) okuphindaphindiwe ekwelapheni ukuphazamiseka okucindezelayo (OCD) kanye ne-Tourette's syndrome (TS). I-International Journal ye-Neuropsychopharmacology, 9 (1), 95-100.