Amakhemikhali asebenzayo kanye nokuphendula kungathinta isikhumba sakho
Ukuhlwitha ebusweni kuyisimo sokwemvelo esingasetshenziswa ngezimbangela eziningi. Isibonelo, izimbangela ezifana nokuphuza utshwala , ukushisa umzimba, ukuzivocavoca, imizwelo, ukuvuvukala, noma ukugula okunye kungenxa yezizathu zobuso obomvu obomvu nezinye izindawo zomzimba.
Ezimweni ezingavamile, ukuqhuma kwesisu kungaba yisibonakaliso senkinga enkulu kakhulu, kuhlanganise nokuba uphawu olukhulu lwe-carcinoid syndrome.
I-carcinoid syndrome yiqembu lezibonakaliso nezimpawu ezihlobene nezicubu zamangqamuzana e-enterochromaffin.
Uma izicubu ezinomdlavuza ezingavamile zibizwa ngokuthi izicubu ze- carcinoid zivikela amanye amakhemikhali nama-hormone egazini lakho, zibangele izimpawu ezihlukahlukene. Lezi zicubu zomdlavuza zingatholakala emathunjini, isithasiselo, i-rectum, amaphaphu, isisu, i-pancreas, ne-thyroid.
Ukuhlwitha ebusweni obangelwa yi-carcinoid syndrome kuyahluka nendawo yesikhumba.
Izimpawu Nezibonakaliso Ze-Carcinoid Syndrome
I-carcinoid syndrome ngokuvamile ivela kubantu abanezikhumba ze-carcinoid eziphambili. Izibonakaliso nezimpawu ze-carcinoid syndrome zizohlukahluka kuye ngokuthi amakhemikhali abekwe engxenyeni yakho yegazi. Ezinye zezibonakaliso ezivame kakhulu zihlanganisa:
Ukushisa ebusweni. Isikhumba sakho singase sishise futhi sishintshe umbala uma sibhekene nokugwinya kwesibuso, okungabangela ukucindezeleka, ukuzivocavoca noma utshwala, noma ungenaso isizathu esicacile nhlobo. Intamo yakho kanye nesifuba esingaphezulu kungase kuhileleke futhi lesi sibonakaliso singadlulela emaminithini ambalwa kuya emahoreni ambalwa noma ngaphezulu.
- Izilonda zesikhumba ebusweni. Ama-Welts, izivunguvungu ezinjenge-spider, kanye nezindawo ezihlukanisiwe ze-purplish, zingase zivele ekhaleni nasemlonyeni ophezulu.
- Uhudo . Amagundane omzimba, kanye nokuvakashela njalo endlini yokugezela, kungenzeka kubantu abanesifo se-carcinoid.
- Izinkinga Zokuphefumula. Ukuphefumula nokuphefumula kungase kwenzeke ngenkathi kwenzeka ukuqhuma ebusweni.
- Ukukhubazeka Kwezinhliziyo. Izinkinga eziphuthumayo zenhliziyo noma ze- valve kungaba uphawu lwe-carcinoid syndrome.
Indlela i-Carcinoid Syndrome ibangelwa ukuxubha ebusweni nokuxilonga
Ukukhuluma ngokwemvelo, kwanda ukwanda kwegazi ngaphansi kwesikhumba esibangela ukuqhuma. Izindawo ezinjengobuso, izindlebe, intamo, isifuba esingaphezulu kanye nezandla ezingaphezulu zinemithwalo yegazi engaphansi kwesikhumba, futhi ukuqhuma kokugeleza kwegazi kungabangela ukuba le mithambo yegazi ikhule futhi igcwaliswe ngegazi (okubizwa ngokuthi i-vasodilation, ephumela ekuphumuleni wezingqamuzana zomzimba ezibushelelezi ngaphakathi kwezindonga zamanzi ezitsheni).
Endabeni ye-carcinoid syndrome, ukuqhuma kubangelwa ukukhishwa kungazelelwe kwamakhemikhali e-vasodilator akhiqizwa amangqamuzana e-enterochromaffin. Ezinye zamakhemikhali ziyi-serotonin, i-5-hydroxytryptamine (5-HT), i-substance P, i-histamine, ne-catecholamines.
I-carcinoid syndrome itholakala ngokuhlolwa okukhethekile komchamo okukala amakhemikhali okuthiwa i-5-HIAA.
Ukwelapha Ukucubungela Ubuso Nge-Carcinoid Syndrome
Ukugwinya kwesifo se-carcinoid syndrome kuphathwa ngokususwa kwesisu futhi kuhlinzekwe imithi ebizwa ngokuthi i-octreotide ehlose ukunciphisa ukufihla kwamakhemikhali e-vasodilating. Ama-antihistamine wendabuko kanye nama-H2-blockers afana ne-cimetidine ne-ranitidine asetshenziselwa ukwelapha i- acid reflux nawo ayesebenzayo ekuphulukiseni ukuqhuma kwesisu kwe-carcinoid syndrome.
Ukwelashwa kwe-carcinoid syndrome ngokuvamile kuhilela ukuphatha umdlavuza. Kodwa-ke, ngenxa yokuthi izicubu eziningi ze-carcinoid azibangeli i-carcinoid syndrome baze baqhubekele phambili, ukwelashwa kungenzeka ukuthi akunakwenzeka. Kulezo zimo, imithi inganciphisa izimpawu zakho ze-carcinoid syndrome futhi yenza ukhululeke ngokwengeziwe.
Umthombo:
I-Carcininoid Cancer Foundation. Ukubuyekezwa kweCarcinoid Cancer.