Yini:
Esinye sezidakamizwa ezisetshenziswa kabanzi ukuphatha izimpawu zesifo se- Alzheimer's . I-Aricept i-FDA-evunyelwe izigaba ezinesizotha, ezilinganiselwe , nezikhulu zesifo.
Indlela Esebenza ngayo:
I-Aricept i- inhibitor ye-cholinesterase evimbela ukwehla kwe- acetylcholine ebuchosheni. I-Acetylcholine idlala indima ebalulekile ememori nasekufundeni; Amazinga aphakeme ebuchosheni asiza amangqamuzana omgogodla ukuxhumana kahle.
Ukusebenza:
Olunye ucwaningo luye lwabona ukuthi i-Aricept ingahle ihlehlise ukuwohloka kwezimpawu ze-Alzheimer ezinyangeni ezingu-6 kuya kwezingu-12 cishe cishe kwesigamu sabantu abayithathayo. Kwabaningi, ukuthuthukiswa akuncane, kodwa kuyadingeka. Ubufakazi be-anecdotal bubonisa ukuthi amaphesenti amancane abantu angazuza ngokuphawulekayo kulo muthi.
Isilinganiso:
I-Aricept iyatholakala kwifomu yethebhulethi noma ifomu lethebhulethi elingahlelekile ngomlomo, futhi livame ukuqala ngo-5 mg ngosuku. Uma kuvunyelwe kahle ngemva kwamaviki angu-4 kuya kwangu-6, umthamo unganyuswa ube ngu-10 mg ngosuku. Uchwepheshe wakho wezokunakekelwa kwezempilo uzonikela isilinganiso esihle kunawe noma othandekayo wakho.
Okuqhamuka uma udla imishanguzo:
Nakuba ngokuvamile kuvunyelwa kahle, imiphumela emibi kakhulu yilezi zinambuzane, isifo sohudo, imvamisa yokunyakaza kokuhamba kwamathumbu, ukuhlanza, ukulimaza, ukuphazamiseka kokulala, ukuhlukunyezwa kwemisipha, ukulahlekelwa ukudla, ukukhathala nokuphelelwa amandla.
Ukubambisana okungenzeka:
Izidakamizwa ezingekho-steroidal anti-inflammatory ( NSAIDs ), njenge-aspirin noma ibuprofen, kufanele zisetshenziswe ngokuqapha ngenkathi ithatha i-Aricept, ngenxa yengozi yokwanda yezilonda zesisu .
Ukuqapha:
Qinisekisa ukuthi utshela udokotela wakho nganoma yimuphi umlando noma izinkinga zamanje ngezilonda zesisu , kufaka phakathi noma yimiphi imithi yamanje ethathwa ngesimo sesisu. Futhi, umuthi unganciphisa izinga lenhliziyo, isimo esaziwa ngokuthi i- bradycardia .
Umkhiqizi:
I-Aricept yasungulwa ngu-Eisai Inc. futhi ivunyiwe yi-FDA ngo-1996.
Njengamanje sisatshalaliswa ngu-Eisai Inc. futhi kuthengiswa yiPfizer Inc.
I-Generic Iyatholakala:
I-Aricept itholakala kufomu elijwayelekile (i-donepezil HCL).
Imithombo:
Mayelana ne-Aricept®. U-Eisai Inc. no-Pfizer Inc. 2007. http://www.aricept.com/about/index.aspx
Imithi ye-Alzheimer's disease ishidi. Isifo se-Alzheimer's Education and Referral Centre, National Institute on Aging. NgoJanuwari 15, 2008. http://www.nia.nih.gov/Alzheimers/Publications/medicationsfs.htm
Imithi elamukelwe yi-FDA ye-Alzheimer's. I-Alzheimer's Association. July 2007. http://www.alz.org/national/documents/topicsheet_treatments.pdf
ScientificWorldJournal. 2013; 2013: 925702. Ukusebenza kwe-Memantine, Donepezil, noma Inhlangano Yabo Ngezifo Ezinzima-I-Alzheimer's Exercise: A Review of Trials Clinic. http://www.ncbi.nlm.nih.gov/pmc/articles/PMC3830825/
-Uhlelwe ngu-Esther Heerema, MSW