I-aplasia cutis congenita yinkinga yesikhumba ebangela ukuba izingane zizalwe ngesikhumba esingekho. I-aplasia cutis congenita ingase ivele ngokwayo noma ibe uphawu lwezinye izinkinga ezifana ne-Johanson-Blizzard syndrome ne-Adams-Oliver syndrome. I-Aplasia cutis congenita ingahle izuze noma ivele ngaphandle komlando womndeni wesimo. Lesi sifo sithinta kokubili abesilisa nabesifazane bazo zonke izizinda ezihlukahlukene futhi kwenzeka kubalelwa ku-10 000 abazalwa.
Abacwaningi abaqiniseki ukuthi yiziphi izakhi zofuzo ezenza i-aplasia cutis congenita, kodwa bakholelwa ukuthi izakhi zofuzo ezithinta ukukhula kwesikhumba zingashintshwa. Kwezinye izimo, isimo singase sibangelwe ukuvezwa kwe-methimazole, isidakamizwa esisetshenziselwa ukuphatha i- hyperthyroidism . Ezinye izifo zingase zibangelwe igciwane noma ukulimala komntwana ngesikhathi sokukhulelwa. Uma isimo sithathwa njengefa , ngokuvamile sidluliselwa umzali oyedwa.
Izimpawu Nezibonakaliso
Ingane ezalwe nge-aplasia cutis congenita iyolahleka isikhumba sesikhumba, ngokuvamile esikhaleni (amaphesenti angu-70 abantu). Ama-patches alahlekile nawo angase avele esihlahleni, izingalo noma imilenze. Iningi lezingane liphethe isikhumba esisodwa esilahlekile esikhumba; Nokho, ama-patches amaningi angase alahleke. Indawo ethintekile ivame ukumbozwa nge-thin membrane ebonakalayo ecacile, ichazwe kahle, futhi ayifuni. Indawo evulekile ingase ibonakale isilonda noma isilonda esivulekile. Ngezinye izikhathi isikhumba esilahlekile sesikhumba siyaphulukisa ngaphambi kokuba ingane izalwe.
Isigatshana esingekho sivame ukuzungeza kodwa singase sibe se-oval, rectangular, noma sezinkanyezi. Yeka ukuthi i-patch enkulu kangakanani, ihlukahluka.
Uma i-aplasia cutis congenita ivela esikhwameni, kungenzeka kube nesici se-skull ngaphansi kwesigatshana esingekho. Kulesi simo, ngokuvamile kuvame ukuguquka kwezinwele ezungeze isiqephu, esaziwa njengesignesha yezinwele zezinwele.
Uma ithambo lithinteka, kukhona ingozi eyengeziwe yokwelashwa. Uma ithambo lisengozini enkulu, isembozo sobuchopho singase sitholwe futhi ingozi yokuphuma kwegazi isanda.
Ukuthola Ukuxilongwa
I-aplasia cutis congenita itholakale isekelwe ekubukeni kwesikhumba somntwana. Izisindo zingabonwa ngokushesha ngemva kokuzalwa. Uma i-patch ilashwa ngaphambi kokuba ingane izalwe, izinwele zizolahleka endaweni ethintekile. Azikho izivivinyo eziqondile zokuhlola i-laboratory ezidingekayo ukuxilonga lesi simo. Iziphambeko ezinkulu kakhulu ze-scalp, ikakhulukazi lezo ezinesibonakaliso sezinwele zezinwele, kufanele ziphenywe mhlawumbe ezingaphansi kwamathambo noma iziphambeko zesisindo esithambile.
Ukwelapha
Ngokuvamile, ukwelashwa okuphela kuphela okudingekayo ku-aplasia cutis congenital ukuhlanzwa okuncane kwendawo ethintekile nokusetshenziswa kwesiliva sulfadiazine ukuvimbela i-patch ukuba ingabe iphelile. Izindawo eziningi ezithintekile zizozipholisa ngamasonto ambalwa, okuholela ekuthuthukiseni isibazi esingenaswele. Amaphutha amancane amathambo futhi avame ukuvalela eyedwa ngonyaka wokuqala wokuphila. Ngokuvamile ukuhlinzwa kungagwenywa ngaphandle kokuthi indawo elahlekile yesikhumba inkulu, noma izindawo eziningana ze-scalp ziyathinteka.
Imithombo:
Crowe, M. (2005). I-Aplasia cutis congenita. eMedicine
Inhlangano Kazwelonke Yezinkinga Ezinzima. U-Aplasia Cutis Congenita