Kubantu abathile abane-MS yokubuyisela kabusha, kuyisinqumo esingcono kakhulu
I-Copaxone (i-glatiramer acetate) yisisetshenziswa esishintsha isifo sokwelapha ukulahla kabusha -ukulungisa i-multiple-sclerosis (i-RRMS), uhlobo lwe-multiple sclerosis lapho izimpawu ziyeza khona kunokuhamba kancane kancane. Ekucwaningweni kweCopaxone kuboniswe ukuthi kusebenza ngokukhethekile ekuvimbeleni ukuqhubekela phambili kwe-RRMS-okungcono kunezinye izindlela zokwelashwa, empeleni.
Akucaci ukuthi i-Copaxone igcina kanjani i-MS iphinde ibuyele emuva nakuba enye inkolelo isekelwe ukuthi imithi yamakhemikhali efana nezidakamizwa ifana ne-myelin sheath ejikeleza amangqamuzana omgogodla futhi isisombululo sempendulo yesimiso sokuzivikela komzimba esihlasela futhi siyayichitha. Amasosha omzimba akhohliswa ekuhlaseleni imithi esikhundleni se-myelin.
Esinye isizathu sokuthi i-Copaxone ivele phakathi kwemithi ye-RRMS ukuthi ayikwenziwa nge-interferon (iprotheni evimbela amagciwane ukuba angaphindaphindi). Izidakamizwa ezisekelwe e-Interferon zinezinye izimo ezimbi ezenza kube ukukhetha okungalungile kwabanye abantu. Nazi ezinye izinto ozokwazi mayelana neCopaxone uma wena nodokotela wakho nicabangela ukungeza kuloluhlobo lwezokwelapha lwe-RRMS.
Isikhumba Sesikhumba kanye Neminye Imiphumela Emibi
I-Copaxone ivela emathinjeni ayethandayo futhi inikezwa umjovo usebenzisa inaliti encane encane eyifakwe ngaphansi kwesigqila-ibe yincinjana ye-2 intshi yesikhumba.
Izingosi ezivame kakhulu izijoka ziyisisu, ingemuva kwengalo, ngemuva kwe-hip, ngemuva, noma phakathi kwethanga. Kungumqondo omuhle ukushintshanisa lapho kudutshulwa khona ngoba kungabangela ama-welts noma ama-welts abuhlungu okuthatha izinsuku eziyisihlanu ukuhamba. Lezi zindlela zokuphendula ngomjovo ngokuvamile ziyancipha ngemva kwezinyanga ezintathu ukuya kwezidakamizwa.
Ukushintshanisa lapho kukhishwa amabhamu nakho kusiza ukuvimbela i-lipoatrophy, ukubhujiswa kwamaseli amafutha ashiya ukucindezeleka okungapheli esikhumbeni nasezikhungweni ezingaphansi. Iningi labantu lizinikela ngamagciwane ngaphandle kwezindawo ezinzima ukuzifinyelela. I-Copaxone shot ingahlaba, kodwa imizuzu embalwa kuphela.
Omunye umphumela ohlangothini lweCopaxone okufanele uwazi ngakho awuvamile kepha uyesabeka: ukuhlaselwa okumangalisayo kwe-panic-type. Lezi zindlela zingabangela ukuqhuma, ukuhlunguzeka kwesifuba, ukushaya inhliziyo, ukukhathazeka, ukucindezeleka komphimbo kanye / noma inkinga yokuphefumula. Lezi zimpawu zenzeka zingakapheli amaminithi womjovo, okwedlule cishe imizuzu engu-15, futhi zihamba zodwa. Abantu abangamaphesenti angu-10 bathatha isipiliyoni se-Copaxone lokhu okungenani kanye, ngokuvamile ngemva kwezinyanga ezimbalwa belashwa.
Ubani ongafanelanga ukuthatha i-Copaxone
I-Copaxone iphephile kubantu abaningi. Abantu kuphela okufanele bangayithathi yilabo abazwela ukukhanya kwe-acetate noma i-mannitol (ishukela utshwala). Azikho ukuxhumana okungaziwa neminye imithi.
Uma ukhulelwe noma ukondla, cishe kuphephile ukuthatha i-Copaxone. Akutholakali ukulimaza ekuthuthukiseni amathumbu ekufundeni kwesilwane, kodwa akubangakho ucwaningo ekukhulelweni kwabantu, ngakho-ke uma ulindele wena nodokotela wakho kuzodingeka uhlole ingozi encane ngaphambi kokuba uqale ukuthatha i-Copaxone.
Kuzo zonke izidakamizwa eziguqula izifo ze- MS, i-Copaxone cishe iyisiphephelo esingasetshenziswa ngesikhathi sokuncelisa. Ayikho idatha eshicilelwe, kodwa noma yikuphi i-Copaxone ebelethweni cishe ibhujiswe emgqatsheni wamathumbu wengane kunokuba ithathwe. Okuhlukile okungahle kube kubantwana abasha.
I-Copaxone ifika ngamandla amabili: Izibhamu ezingamatshumi amahlanu-milligram zonikezwa nsuku zonke futhi izijovo ezingama-40-milligram ezinikezwa kathathu ngesonto. Izindleko zegama le-Copaxone libiza phakathi kuka- $ 6,000 kuya ku-$ 7,500 ngenyanga kodwa kunezifomu ezijwayelekile ezivame ukungabi namanani aphansi. I-Copaxone kanye namafomu ayo ajwayelekile ahlanganiswa nomshuwalense omkhulu wezokwelapha futhi, ngakho uma kuba yisisulu sakho semithi yokwelapha se-MS kufanele ube nenkinga encane yokuyifaka.
> Imithombo:
> Guillermo Izquierdo, uNauri Garcia-Agua Soler, uMacarena Rus, no-Antonio Jose Garcia-Ruiz, "Ukuphumelela kwe-Acetate ye-Glatiramer Uma kuqhathaniswa nezinye izindlela eziningi zokwelapha izifo ze-sclerosis." I-Brain Behav . 2015 Jun; 5 (6): e00337.
> National Multiple Sclerosis Society. "I-Copaxone."
> Ukuphathwa Kwezokudla Nezidakamizwa zase-US. "I-FDA ivumela i-Copaxone yokuqala yokukhiqiza i-Copaxone Yokuphatha I-Multiple Sclerosis." Ngo-Apr 16, 2015.