Ingabe I-Cancer Lung Izuzwe Ifa?

by ULynne Eldridge, MD

Uma Umuntu Emndenini Wami Engenayo I-Cancer Lung, Ingabe Nginokuthi Ngikuthole?

Kuyaziwa ukuthi ezinye ze-cancer, ezifana nomdlavuza we-ovarian nomdlavuza we-colon, ugijime emindenini. Ngisho noma indima yokuzalwa emdlalweni wamaphaphu engaziwa kahle, ukuba nomlando womndeni womdlavuza wamaphaphu kwandisa ingozi yethu ngezinga elithile. Umdlavuza wamaphaphu we-Hereditary uphakeme kakhulu kwabesifazane, abangabonisi futhi nalabo abanomdlavuza wamaphaphu ekuqaleni (umdlavuza wamaphaphu okwenzeka ngaphambi kweminyaka engama-60).

Konke, kulinganiselwa ukuthi amaphesenti angu-1.7 wamanqamu wamaphaphu kuze kube neminyaka engu-68 ayifa. Izici eziningana zihlobene nomdlavuza we-lung we-lung, okufaka:

Yeka ukuthi ilunga lomndeni lihlobene kangakanani

Ukuba nelunga lomndeni wokuqala (umzali, umntakwethu noma ingane) ngomdlavuza wamaphaphu cishe kabili ingozi yokuthuthukisa umdlavuza wamaphaphu. Le ngozi ingaphezulu kwabesifazane futhi encane kumadoda futhi inamandla kulabo abangabonisi ngaphezu kokubhema. Ukuba nesihlobo sesibili (unina, umalume, umshana noma umshana) ngomdlavuza wamaphaphu uphakamisa ingozi yakho ngamaphesenti angaba ngu- 30 .

Isimo sokubhema, i-Cancer Lung, ne-Heredity

Ababhemayo abahlakulela umdlavuza wamaphaphu abanamathuba okuba nomlando womndeni kunabangaboni abangakha umdlavuza wamaphaphu. Nokho, lokho kusho labo abanesifo somdlavuza emaphashini, ukubhema kubonakala kukwandisa leyo ngozi.

I-Cancer Lung ku-Non-Smokers

Uhlobo lwe-Cancer Lung ne-Heredity

Izifundo ziyahlukahluka ezinhlobonhlobo zamanqamu emaphaphu anesici esikhulu kakhulu, kepha labo abanamdlavuza wamaphaphu angenalutho , ikakhulukazi emaphasheni adenocarcinoma cishe banomlando womndeni womdlavuza wamaphaphu kunelawo amancane angama-cancer wamaphaphu amancane .

Ukuthola kwamuva ukuthi abangewona abokubhema abanomdlavuza we-cell wamaphaphu okungewona omncane abanezinambuzane ezine- EGFR mutation cishe amathuba okuba nomlando womndeni womdlavuza wamaphaphu kunelabo abane- ALK rearrangement noma i-KRAS mutation.

I-Genetic Cancer Gene (BRCA2) kanye neengozi ye-Cancer Cancer

Muva nje itholakale ukuthi abantu abanokuguqulwa kwe-BRCA2 - enye yezinguquko ezitholakala kubantu abanomdlavuza webele we-genetic - zisengozini enkulu yokuthuthukisa umdlavuza wamaphaphu.

Lokhu kuguqulwa kutholakala kumaphesenti angu-2 wabantu baseYurophu abazalwa futhi bazuze njengefa elikulo mkhuba ovelele we-autosomal. Ngaphandle kokwandisa ingozi yomdlavuza wesifuba nomdlavuza we-ovarian (phakathi kwabanye,) ukubhema nokuguqulwa kwatholakala ukuthi cishe cishe kabili amathuba okuba nomdlavuza wamaphaphu. (Ingozi yomdlavuza wamaphaphu yayiphakeme kunalabo ababhemayo abanokuguqulwa komzimba.) Ababhemayo abathwala lolu daba kubonakala sengathi banomngcipheko okhulayo ikakhulukazi emdlalweni wesifo somdlavuza wesifo samaphaphu , uhlobo lomdlavuza ongasona omncane wamaphaphu. Ngalesi sikhathi, azikho izincomo ezithile eziphathelene nokuhlola abantu abanezimo eziguquguqukayo, kodwa labo abathintekayo bangase bafise ukukhuluma nodokotela babo mayelana nokuhlolwa kwe-CT yomdlavuza wamaphaphu.

I-Cancer Lung ixhunywe ne-Genetic Cancer Gene (BRCA2)

Umjaho, i-Cancer Cancer, ne-Heredity

Abomnyama abanezihlobo ze-first-degree banengozi enkulu yomdlavuza wamaphaphu kuqala kunabamhlophe. Le nengozi ikhuphuka kubantu ababhemayo.

Amanye ama-Cancers neHereditary Lung Cancer

Ngokuvamile, ukuba nomlando womndeni wama-khansa ngaphandle komdlavuza wamaphaphu akubonakali ukwandisa ingozi yokuthi uzokwakha umdlavuza wamaphaphu. Ngakolunye uhlangothi lwe-equation, noma kunjalo, labo abahlakulela umdlavuza wamaphaphu oyinhloko kakhulu kunamathuba amaningi kakhulu okuba nesifo somdlavuza esiba nomdlavuza wabo.

Yini Okufanele Ngiyenze Uma Nginomlando Womndeni Wengculaza Yengculazi?

Ukuhlolwa kwe-CT yomdlavuza wamaphaphu kuyindlela yokhetho kwabanye abantu, nakuba okwamanje kunconywa kuphela kulabo bantu abaneminyaka engama-55 no-74 ubudala, ababhema noma abayekile eminyakeni engu-15 edlule, futhi banomlando weminyaka engu-30 wamapaki ukubhema. Kuye ngezici zakho zobungozi, wena nodokotela wakho bangakhetha ukukhetha ukuhlola ngaphandle kwalezi zimingcele. Ngaphambi kokuba sithembeke ngalezi zakhi zofuzo ezinikezwe umama nobaba, kudingeka sikhumbule ukuthi izimbangela eziningi zomdlavuza wamaphaphu zivinjelwa. Ukuyeka ukubhema (uma ubhema), ukuhlola ikhaya lakho nge- radon , ukudla ukudla okunempilo , ukuzivocavoca nokuqapha ukugwema izimbangela zomsebenzi kungasiza ekunciphiseni ingozi yokuba nomdlavuza wamaphaphu noma unomlando womndeni noma cha.

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