Ukungenwa kwe-Eosinophilic
I-Eosinophilic esophagitis (EE) isifo esivezwe ukuvuvukala kwesifo (ingxenye yomzimba ehlangene nomphimbo nesisu) obangelwa i-white blood cell, i- eosinophil . Izimpawu ze-EE zingabhekana nokukhwabanisa okukhulu, kunzima ukugwinya, ukuphazamiseka kokudla endaweni, isicanucanu, ukuhlanza nokulahlekelwa isisindo. Kubonakala sengathi kunezinye izinkinga ezihlobene neminyaka ubudala, nezingane ezincane ezinezimpawu eziningi zokulahlekelwa isisindo, kanye nezingane ezindala kanye nabantu abadala abakuthola ukudla kanye nobunzima bokugwinya.
Akucaci ukuthi yiziphi izimbangela ze-EE, nakuba lesi sifo singase sihlobene nezinye izifo ezithathelisayo, ikakhulukazi isifuba somoya . Abantu abane-EE kaningi banomlando womuntu siqu noma womndeni wezinye izifo ezithathelisayo ezifana ne-hay fever, ukungezwani kokudla, nesifo se-asthma. Muva nje, kuye kwaba nezifundo ezibonisa ukuhlangana phakathi kokudla kanye nokudla kwemvelo kanye ne-EE.
Yisiphi Isifo Sobungozi Esivame Ukwenza I-EE?
Ucwaningo oluhlukahlukene luye lwabonisa ukuthi iziguli ezine-EE zinemizamo emihle yokuzivivinya umzimba ekudleni okuhlukahlukene nokuthi ukugwema lokhu kudla kwaholela ekusombulweni kwezimpawu ze-EE. Ukudla okubikwe ukuthi imbangela ye-EE ifakiwe ubisi, amaqanda, amantongomane, i-shellfish, i-peas, inyama yenkomo, inkukhu, inhlanzi, i-rye, ummbila, ubhontshisi, amazambane, ama-oats, utamatisi, nokolo. Kulezi, izifo ezivame kakhulu zokudla kukhona ubisi, amaqanda, ukolweni, i-rye, kanye nenkomo.
Izifo eziphilayo, ezifana ne-pollens, isikhunta, i-cat, inja kanye no-dust mite allergens nazo zingabandakanyeka ekuthuthukiseni i-EE.
I-EE ihlolwe kanjani?
Ukuxilongwa kwe-EE kuvamise kwenziwa ngokwenza i-biopsy ye-esophagus, nobufakazi bokuthi i-eosinophils ingena emathisini. I-biopsy yenziwa nge-endoscopy (ikhamera efakwe ngaphakathi kwendawo), ngokuvamile i-gastroenterologist. Kunezinye izifo eziningi ezingabangela ama-eosinophil ezicubu zesifo, kuhlanganise nesifo se-reflux se-gastroesophageal (GERD), ukutheleleka kwe-parasitic, ukutheleleka kwe-fungal, isifo sofuba esishubile, amanyevuza, ukuhlanza okuvamile kanye nabanye.
Lezi zifo kudingeka zikhishwe ngaphambi kokuba i-EE ingatholakaliswa.
Uma i-EE itholakale, i-allergenist ngokuvamile izokwenza ukuhlolwa kokunciphisa umzimba, okubandakanya ukufuna ukudla okunomsoco nokudla kwemvelo, njengalezo ezibalwe ngenhla.
I-EE iphatheke kanjani?
Isivivinyo sokugwema ukudla lapho umuntu enesifo sokuvivinya umzimba ngokuqondile kuyindlela yokuqala yokwelapha ye-EE. Uma umuntu enemizamo eminingi yokuvivinya umzimba, kungase kubalulekile ukuthi ushintshe ekudleni okubandakanya i-formulaal elemental (amaprotheni aphule phansi ezakhiweni eziyisisekelo, okuthiwa ama-amino acids).
I-Corticosteroids ijwayele ukusetshenziselwa ukwelapha i-EE uma ukugwema izifo eziqeda ukwelashwa kungaphumeleli kahle izimpawu. I-Steroids ingasetshenziswa njengamaphilisi, njenge-prednisone, noma njengendlela yokwelapha, njengokusebenzisa i-steroids engathintiwe (isibonelo, i-Flovent) ngokujwayelekile isetshenziselwa i-asthma, ngaphandle kokuthi imithi igxotshiwe, ingagxilwanga. Lokhu kubangela ukulethwa kwemithi ngokuqondile kuleso sikhungo. Ngokuvamile, imithi ye-GERD nayo inikezwa iziguli ezine-EE.
Ufuna ukuqhubeka ufunda? Thola mayelana ne- Food Protein-Induced Enterocolitis Syndrome , isifo esilinganisa ukudla kokudla ezinganeni ezincane.
> Imithombo:
> Norvell JM, Venarske D, Hummell DS. I-Eosinophilic Esophagitis: Indlela Yokuthola I-Allergist. Ann Ukuzivocavoca Isifo Somoya Immunol. 2007; 98: 207-215.
> Rothenberg ME. Ukuphazamiseka Kwezinsipho Eosinophilic. J Allergy Clin Immunol. 2004; 113: 11-28.