I-Pigmentation ye-Colon ne-Rectum
I-melanosis coli yinkinga lapho kukhishwa khona izinambuzane ezihlanganisa uboloni (amathumbu amakhulu) kanye ne-rectum. Lesi simo sivame ukukhonjwa ngesikhathi se- colonoscopy .
Ngokuvamile, i-melanosis coli iveza ngokwayo umbala omnyama noma omnyama. Ukuguqulwa kombala akubonwanga ngokufanayo kuwo wonke amakoloni, kodwa kunalokho kubonakala kubonakala ngokwengeziwe ezingxenyeni zokuqala nezingaphakathi.
Ngezinye izikhathi, izinguquko ze-pigment nazo zingabonakala emathunjini amancane , isimo esibizwa ngokuthi i-melanosis ilei.
I-Melanosis coli ibizo layo ngoba kwakucatshangwa ukuthi ukushintsha kombala kwakuwumphumela we-pigment melanin. Ucwaningo oluthile lwamanje lukhomba i-lipofuscin njengoba i-pigment-ikhiqiza umbala omnyama.
Izimbangela
Odokotela ngokuvamile babona i-melanosis coli ezigulini ezibhekene nokuqashwa okungapheli . Lokhu kuye kwaholela ekuqinisekiseni isixhumanisi esiqinile phakathi kokusetshenziswa kwama- herbal laxatives aqukethe ama- anthraquinones nokubonakala kwe-melanosis coli. I-Melanosis coli ingase ibonakale ezinyangeni ezine ngemuva kokusebenzisa njalo ama-herbal laxatives, kodwa izophela phakathi nezinyanga eziyisithupha kuya kwezingu-12 ngemuva kokusetshenziswa kokukhipha isisu.
Ama-laxatives ane-anthraquinone ahlanganisa:
- I-Aloe latex
- I-Cascara sagrada
- I-Frangula
- I-Rhubarb (i-Rhuem)
- Senna
Akukaziwa nje ukuthi kungani lezi zinhlayiya zenza izinguquko ze-pigment of melanosis coli.
Ezinye izazi ze-theorists ziphakamisa ukuthi imiphumela yokuhlanza ye-laxatives ibangela ukushona kwamaseli e-epithelial emgqeni wekoloni. Ngakho-ke, izinsalela zala maseli zihlelwe ukuthi zenziwe amanye amaseli, ngenxa yalokho okwakhiwa kwezinto ezibonakalayo ezinobunzima obubomvu obufaka amathumbu emathumbu emathunjini.
Ngokuthakazelisayo, ezimweni ezingavamile, i-melanosis coli ingabonakala ezigulini ezingenayo ukuqashwa noma zingasebenzisi laxatives ngenhla.
I-Melanosis Coli ne-Cancer Risk
Abaningi be- gastroenterologists bacabangela ukuthi i-melanosis coli ayiyona ingozi. Izifundo azitholanga inhlangano phakathi kwe-melanosis coli kanye nengozi eyengeziwe yokwelashwa kombala . Lokhu akusho ukuthi ayikho enye, nje ukuthi kunzima ukuthola inhlangano enjalo.
Isizathu sokuntula okucacile kulesi sihloko sithinta ubudlelwane obungabonakali bokuqothulwa nomdlavuza. Izifundo zibonise ubudlelwane phakathi kokuqothulwa nomdlavuza wekoloni, kodwa aziwa ukuthi kungani. Abanye bacabanga ukuthi kungenxa ye- motility kancane yokuqothulwa okubangelwa ukuthi ama-carcinogens abe nokuxhumana isikhathi eside ngamaseli emathumbu. Noma, kungenzeka ukuthi izici ezanikele ekuqotheni ngokwabo, njengokudla okuncane fiber , yisona isizathu esenza lokhu kubungozi.
Ukwelapha
Ayikho inqubo eqondile yokuqeda i-melanosis coli. Ngokuvamile, isincomo singcono ekuphathweni okuthuthukisiwe kokuqunjelwa ngokwayo, kanye nesincoma sokuyeka ukusebenzisa amakhemikhali ane-anthraquinone. Uma lezi zinxanxathela ziphelile, kungenzeka ukuthi isimo sizobe sinciphise ngokuphelele noma kancane.
> Imithombo:
> Biernacka-Wawrzonek D, Stępka M, Tomaszewska A, et al. I-melanosis coli ezigulini zomdlavuza wekoloni. Ukubuyekezwa kwe-Gastroenterology . 2017; 1: 22-27. doi: 10.5114 / pg.2016.64844.
> Freeman, H. "Melanosis" emathunjini amancane nezinkulu World Journal of Gastroenterology 2008 14: 4296-4299.
> Li X, et. al. I-hertopathology ye-melanosis coli nokuzimisela kwezakhi zofuzo ezihlotshaniswa ngokuhlaziywa kokuqhathaniswa kwe-microarrays Imibiko Yezokwelapha Ze-Molecular 2015 12: 5807-5815.