I-Neutropenia Enamandla Ebandayo

I-neutropenia engavamile yokubeletha ichaza lesi simo ngokuphelele. Kuyinto yokuzalwa (okusho ukuthi uzalwa nayo) isimo ne- neutropenia eqinile (echazwe ngokuthi inani le-neutrophil

Ziyini Izimpawu?

Izimpawu ngokuvamile ziqala maduzane ngemva kokuzalwa.

I-neutrophils yimihlobo yegazi elimhlophe elibhekene ne-bacterial infections. Ukubala okunamandla kakhulu kwe-neutrophil kwandisa ingozi yakho yokutheleleka kwebhaktheriya. Umkhuhlane uyisifo esivamile, kodwa lokhu kungenxa yokutheleleka akuyona i-neutropenia. Ukukhubazeka kokuzalwa ngokuvamile akubonwanga.

• I-Otitis media (izifo zendlebe)
• Cellulitis (ukutheleleka kwesikhumba)
• Izilonda zomlomo
• I-Gingivitis (ukuvuvukala kwe-gum)

Utholakala kanjani?

Kungenzeka ukuthi ngesikhathi esisodwa salezi zifo, udokotela wakho uzothola inani eliphelele legazi (CBC) . I-neutropenia enamandla (

Uma ngabe i-neutropenia eqinile ikhonjisiwe, udokotela wakho angase acabange ekubhekisela ku-hematologist, udokotela onguchwepheshe wezifo zegazi.

Okokuqala ungase ube ne-CBC ekhishwe izikhathi ezingu-2 kuya kwezi-3 ngeviki ukulawula i-neutropenia ye-cyclic (isimo esibi kakhulu) njengesizathu.

Isinyathelo esilandelayo yi-bone marrow biopsy. Lokhu kuhlolwa kuhilela ukukhipha ucezu oluthile lwesithambo esivela esikhwameni sakho ukuze uhlole umongo wesithambo, indawo lapho amangqamuzana egazi amhlophe enza khona.

E-neutropenia ekhulelwe engakazalwa, amangqamuzana akwenziwa ngokuvamile kodwa ekuqaleni abuye afe ngaphambi kokukhululwa.

Uma umnkantsha wakho uhambisana ne-neutropenia ebanga kakhulu, udokotela wakho cishe uzothumela ukuhlolwa kofuzo ukuze anqume ukushintsha okuthile okukhona. Lokhu kubalulekile njengoba kuzokwenquma ukuthi ungayidlulisela kanjani lesi sifo noma izingane zakho.

Yiziphi Izindlela zokwelapha?

• Isici se-Granulocyte Colony Stimulating (G-CSF noma i-filgrastim): I-G-SCF inikezwa njengama-subcutaneous (ngaphansi kwesikhumba) imijovo nsuku zonke. Le mithi ivuselela ukukhiqizwa komnkantsha we-bone kanye nokuvuthwa kwe-neutrophils. Umgomo ukuletha inani le-neutrophil ngokujwayelekile ukuze kuvinjelwe ukutheleleka.
• Ukufakelwa kwe-bone lomnkantsha: Ukufakelwa komnyosa we-bone kungaba ukwelapha. Lokhu kuvame ukubhekwa kubantu abanempendulo embi ku-G-CSF. Uma uthola ukufakelwa komnyofu wesibhakabhaka kumntakwethu, kubalulekile ukuqinisekisa ukuthi awunayo ifomu elibi le-neutropenia engavamile.
• Ama-antibiotics: Uma une-neutropenia ebanga kakhulu futhi uthuthukise umkhuhlane, kufanele ufune usizo lwezempilo ngokushesha. I-fever ingase ibe yodwa uphawu lwe-infection enkulu. Umsebenzi wegazi kufanele uthunyelwe ukuze ubone ukuthi kungenzeka yini imbangela yokutheleleka. Phakathi nalesi sikhathi uzobekwa kwi-IV (nge-vein) antibiotics uma unesifo.

Ingabe Kukhona Ukukhathazeka Kwesikhathi Eside?

Ngokwelashwa okungcono, isikhathi sokuphila kwabantu abane-neutropenia engakazalwa esisanda kukhula kakhulu. Njengoba uneminyaka ekhulayo, usengozini enkulu ye- myelodysplastic syndrome (i-MDS) ne-leukemia (ikakhulukazi i-lemonemic leukemia ephawulekayo) eqhathaniswa nomphakathi jikelele. Le ngozi yayicatshangwa ukuthi iyesibili ekwelapheni kwe-G-CSF kodwa ibonakala iyinkinga yalesi simo.

Ukwelashwa nge-G-CSF kungaholela ekutheni i-splenomegaly (ukukhuliswa kwesipere). Ngezinye izikhathi lokhu kukwanda kobukhulu be-spleen kuzobangela inani leplatelet eliphansi (thrombocytopenia). Uma i-thrombocytopenia inzima, ungadinga i-splenectomy.