Imbangela Ebonakalayo Yezinhlungu Nezinga Lokushisa Ukuhlukunyezwa ku-Fibromyalgia
Uma uhlala ne- fibromyalgia , cishe uyazi ezinye zezimpikiswano. Akugcini nje kuphela ukuthenga yonke into ngaphandle kwesizathu esicacile, kodwa kubonakala sengathi akekho owazi ukuthi kungani lokhu kwenzeka. Futhi kuze kube yilapho sesiyazi ngempela imbangela yezimpawu, kunzima ukuthola ukwelashwa okuphumelelayo. Lokho kusho ukuthi isifundo se-2013 singase sibhekisele kumbangela omkhulu wobuhlungu obubanzi kanye nezinye izimpawu ezibonisa i-fibromyalgia.
Ukubukeza Okufushane kwe-Fibromyalgia Nezizathu Ezenzekayo
I-Fibromyalgia yisimo esibangela ubuhlungu obubanzi futhi sithinta cishe abantu abayizigidi ezingu-6 e-United States. Ngesikhathi samanje, odokotela kumele benze izibonakaliso nezimpawu ezitholakala emlandweni kanye nokuhlolwa komzimba wedwa okwenza ukuxilongwa . Lesi simo ngokuvamile asiqondwa kahle, futhi ukukhungatheka kokuphila nesimo esingenalo ukuhlolwa okucacile okuhlolisisa ukushiya abantu abaningi abane-fibromyalgia bezwa bodwa futhi bebuzwa yibo abangayiqondi. Ukucwaninga ngokubheka izimbangela ezibangelwa i-fibromyalgia kuye kwaphazamiseka, futhi ngaphandle kwesizathu esaziwayo, ukuhlolwa kokuxilongwa noma ukwelashwa okuhloswe ukushintsha imbangela kuyaphela.
Isizathu Esinokwenzeka Sokuba I-Fibromyalgia: Amantongomane Omningi
Ngemva kokucubungula amathuba avela ku-P kuya kuma-hormone, abacwaningi baye bakhathazeka mayelana nezinqubo eziqondile ezivela kumpawu ze-fibromyalgia.
Kodwa manje basho ukuthi abantu abane-fibromyalgia bangase babe nezinzwa eziningi ezingaphezu kwezinto ezithile ezingxenyeni ezithile ze-circulatory system. Lezi "zinzwa ezengeziwe" zingabangela ubuhlungu obukhulu nobubele obukhulu, ukungcolisa ukugeleza kwegazi, futhi kwenze kube nzima ngomzimba ukulawula ukushisa kwangaphakathi.
Izintambo ze-Arteriole-Venule nokuthi kungani zibalulekile
Nasi isifundo se-anatomy esheshayo ukukusiza ukuthi uqonde lokhu okutholayo.
Kuhlelo lwakho lokujikeleza , unezinhlobo eziningana zemithambo yegazi. Igazi lishiya ohlangothini lwesobunxele lwenhliziyo emithanjeni emikhulu. Leli gatsha liya emithanjeni encane bese i-arterioles. Ama-arterioles athola amancane futhi amancane, njengoba amagatsha omuthi athola amancinci futhi amancane, futhi agcina ama-capillari , amancane kakhulu emithanjeni yegazi lapho ukushintshaniswa kwe-oksijeni nezakhi zomzimba kwenzeka khona. Lapho ephuma ama-capillary, igazi lihamba phakathi kwamagciwane, kuya emithanjeni emikhulu futhi emikhulu, ekugcineni libuyela ngakwesokudla senhliziyo.
Lezi zinhlobo ezimbili zemithambo yegazi esibheka kulo mbono yi-arterioles kanye nama-venules. Ngesinye isikhathi, ngokususelwa ekuguquleni kwegazi okudingekayo endaweni ethile yomzimba, igazi lidlula ama-capillari bese lihamba ngokuqondile kusuka e-arterioles kuya emasongweni. Cabanga ngamapayipi okwesikhashana. Ama-arterioles kanye nama-venules ahlukene ngamapayipi, futhi adinga ama-valve ukuwaxhuma. Lawo ma-valves abizwa ngokuthi ama-arteriole-venule shunts (AVS.)
Ukuvinjwa kwe-venule yokuguqula ukulawula ukuthi ngabe igazi lakho lihlala ezitheni ezinkulu noma ligeleza zibe ezincane ezinama-capillari. Yileyo ndlela umzimba wakho olawula ngayo ukushisa, okuguqulwa emzimbeni wakho ngegazi. I-AVS ivuliwe futhi ivaliwe yizinzwa ezikhethekile, ezibona igazi ligeleza kanye nobuhlungu nokushisa.
(Ungazibona ngokwakho ngokubheka ukuthi umzimba wakho uthola kanjani pink uma ushisayo futhi uguquka uma ubanda.)
Kulesi sifundo, ososayensi bathola ukuthi ababambiqhaza nge-fibromyalgia babe nesiguli sezinzwa ezengeziwe ezigijima ku-AVS. Izisindo ezengeziwe zisho ukungena okunomqondo okwedlulele, futhi ngenxa yalokho ukusabela ngokweqile ezinhlokweni ezifana nobuhlungu nokushisa.
Kusho ukuthini?
Ngakho-ke, kunezindebe ezengeziwe ezithatha ngokweqile ubuhlungu nokushisa, futhi lezi zinzwa zilawula ukuzivikela kwe-arteriole-venule, kodwa lokhu kusho ukuthini? Lapho sicwaninga isimo ezifana ne-fibromyalgia singathola izinguquko zesakhiwo emzimbeni, kodwa lokho kushintshela kanjani ukusebenza.
Futhi lokho kungashintsha kanjani emsebenzini kubangela izimpawu esizizwayo?
Ama-Nerve Extra Extra Mean "Extra Thermostats"
Kulesi sifundo, abacwaningi babheka imizwa nemithambo yegazi esandleni. Asisazi ukuthi lezi zinzwa ezengeziwe ziphezu kwemizimba yethu, kodwa uma kunjalo, kungasiza ukuchaza ukuthi kungani abantu abane-fibromyalgia belimaza yonke indawo. Kungase futhi kuchaze ukuthi kungani izintambo zethu zangaphakathi ziphezu kwendawo .
Izimpikiswano zegazi
Ngaphandle kwezindaba ze-thermostat, yizinkinga zokugeleza kwegazi. Igazi lithwala i-oksijeni nezakhi kumzimba, kodwa uma umzimba unenkinga yokuqondisa ukugeleza kwegazi ngokuphendula, imisipha iyanqatshwa, ngakho-ke ibuthakathaka. I-actic lactic iyakhuphula futhi ibangele ukuzwa okuvuthayo okungenzeka ukuthi ujwayelene nakho.
Ukwengeza, ingabe uke wabona ukuthi izikhonkwane ezibuhlungu-nezinaliti uzizwa lapho unyawo noma isandla ulele? Kubangelwa ukugeleza kwegazi okungenele esifundeni somzimba (okuthiwa yi-ischemia), futhi odokotela baye baba nesikhathi eside bakholelwa ukuthi i-ischemia inomthwalo weminye ubuhlungu be-fibromyalgia .
(Ungase ufise ukubuye ubuyekeze ubuhlobo be- serotonin nokugeleza kwegazi ku-fibromyalgia yombono ohlukile wokuthi kungani ukungena kwegazi kungase kwenzeke.)
Indlela Ukuthola Lokhu Kungabangela Ukuhlolwa Kokuhlola noma Ukwelashwa Kwe-Fibromyalgia
I-Fibromyalgia njengamanje isifo sokuxilongwa kwemithi, okusho ukuthi ayikho ukuhlolwa kwegazi noma isifundo se-radiological esingenziwa ukuze kuqinisekiswe noma kungabandakanyi ukuxilongwa. Esikhundleni salokho, i-fibromyalgia ivame ukuxilongwa ngokuxoshwa ngokusekelwe emlandweni oqaphileyo, ukuhlolwa ngokomzimba, kanye nezimo ezilawulayo esinezivivinyo zokuxilonga.
Abacwaningi kulolu cwaningo bakholelwa ukuthi-njengoba lokhu kutholakala kuyinkinga ecacile-lokhu kutholakala kungabangela ukuhlolwa kocwaningo. Ngaphezu kwalokho, ngoba ukungajwayelekile kuye kwaphawulwa, ukubuka izindlela zokuguqula lokho okungavamile kungaholela ekukhethweni kokwelapha esizayo. Konke okubonakala kubethembisa, kodwa ngakho-ke yenza nezinye izifundo eziningi. Isikhathi sizokutshela.
Ukulinganiselwa Okungenzeka Kule Sifundo
Nansi into okufanele uyikhumbule ngalolu cwaningo: Yayixhaswe ngemikhiqizo emibili ekhiqiza imithi ye-fibromyalgia Cymbalta (duloxetine) no- Savella (milnacipran.) Ukukhululwa komshini ekutholeni okushiwo ukuthi izidakamizwa ezingaphezu kwalokho zingenza ukuthi lezo zidakamizwa ezimbili zisebenze; bangase basize ukuhlenga izinzwa ezingaphezulu. Lokhu okutholayo kuphakamisa ukungabaza mayelana nezindlela ezintsha zokwelapha njengoba izinkampani ezidakamizwa azivame ukuba nomkhuba wokuphishekela izidakamizwa ezintsha uma zingakhuphula ukuthengisa kwalezo ezisemakethe.
Futhi, lokhu kwaba isifundo esincane nabesifazane abangu-24 kuphela. Sidinga ucwaningo oluningi ngaphambi kokuthi singasho, ngaphandle kokungabaza, ukuthi lokhu kwenzeka emzimbeni wethu. Lokhu kuyinkimbinkimbi ezithakazelisayo ezifanele ukutadisha okuqhubekayo, kodwa ngethemba lokuthi abanye abacwaningi bazolandelwa ukunciphisa ukukhathazeka mayelana nokuthanda.
Ngaphansi Kwezimbungulu Eziningi Njengamathuba Asemandleni Ezimpawu Ze-Fibromyalgia
Inkolelo yokuthi izimpawu ze-fibromyalgia zingase zihlotshaniswe nesisindo esidlulele kwi-AV shunts okubangelwa ubuhlungu nokushisa kwezinga lokushisa kuyathakazelisa. Uma kukhona iqiniso kulo mbono, ngeke kukhulume kuphela ukuthi ukuhlolwa kokuhlolwa kwe-fibromyalgia kungahle kuthuthukiswe, kodwa ukuthi ukwelashwa okubhekiswe kulokhu okungajwayelekile kungenziwa futhi. Njengoba kuphawuliwe, ukucwaninga okukhulunywe ngakho lapha kwakuncane kakhulu, futhi ucwaningo olwengeziwe luyadingeka ukuze kutholakale ukuthi kufanelekile ukuphishekela
Kubantu abaphila nokukhungatheka kwesimiso esingenabuhlungu kuphela kodwa esingenaso ukuhlolwa okuqondile kokuhlola, le mbono ingase ihlehlise ukucwasa nokuzihlukanisa okuyizinto eziphawulekayo zokuphila nesifo esingelapheki esingavamile.
> Imithombo:
> Albrecht, P., Hou, Q., Argoff, C., Storey, J., Wymer, J., noF Rice. Ukubhuka okungejwayelekile kwe-Peptidergic Ukutholakala Kokutholakala Kwezingqimba Ze-Cutter Arteriole-Venule (AVS) Esikhumbeni Esimhlophe Sama-Fibromyalgia Iziguli: Umphumela Wezinhlungu Ezijulile Zomzimba Nekhathala. Imithi Yezinhlungu . 2013. 14 (6): 895-915.
> Albrecht, P., no F. Rice. I-Fibromyalgia Syndrome I-Pathology and Environmental Influences on Afflictions Ngezimpawu Ezingaqondakali Zemithi. Ukubuyekeza ku-Environmental Health . 2016. 31 (2): 281-94.
> Sluka, K., noD. Clauw. I-Neurobiology ye-Fibromyalgia Nokuhlupheka Okuvamile. I-neuroscience . 2016. 338: 114-129.