I-Thyroglobulin, eyaziwa nangokuthi i-Tg, iyiprotheni ekhiqizwa kwi-thyroid eguqulwa ibe ama-hormone e-thyroid T3 no-T4, okusiza umzimba ukulawula umzimba. I-Thyroglobulin yenziwa ngamangqamuzana e-follicular we-gland yegciwane, elitholakala engxenyeni engezansi engaphansi kwentamo yakho. Ikhishwa ngamaseli ajwayelekile ajwayelekile futhi anomdlavuza.
Uma igciwane lakho le-thyroid lisuswa ku- thyroidectomy , awukwazi ukwenza i-thyroglobulin. Lokhu kusho ukuthi ukutholakala kwayo kungasetshenziswa njengendlela yokumisa izifo ezithile zomdlavuza wegciwane le-papillary nomdlavuza we-follicular we-thyroid. Uma itholakala, kusho ukuthi ezinye izicubu ze-thyroid noma i-tumor ihlala noma ibuyile.
I-Thyroglobulin ihlaselwa yi-autoantibodies kwezinye izifo ezibangelwa yi-autoimmune, eziholela ezimweni ze -roid ezingabangela ukuthi i-thyroid engasebenzi kakhulu (i- hyperthyroidism ) noma i-thyroid engasebenzi ( hypothyroidism ).
Ukuhlolwa kokuxilongwa
Kuyinto evamile ukuba ne-thyroglobulin encane itholwe egazini, kepha ukuhlushwa okuphezulu kungakhomba izimo ezihlukahlukene zezifo, hhayi konke okubangelwa umdlavuza.
Udokotela wakho angase avivinye i-thyroglobulin uma ecabanga ukuthi i-thyroid yezinkinga eziphazamisayo ezifana ne-hyperthyroidism, i-Graves isifo noma i-thyroiditis. Uma uphathwa ngemithi yokwelashwa, angase alandele amazinga akho we-thyroglobulin ukuze abone ukuthi aphumelele noma adinga ukulungiswa.
Sebenzisa njengoMakaki we-Tumor
Isizathu esivamile sokuhlola i-thyroglobulin sisemdlavuza wegciwane. Isivivinyo se-thyroglobulin asisetshenziselwa ukuthola noma ukuhlolisisa umdlavuza ngokwawo, kodwa sisetshenziselwa ukufaka uphawu lwe-tumor ngemuva kokuthola ukuthi yi-biopsy. Uma amazinga aphakeme ngaphambi kokuba isifo segciwane sisuswe, cishe kungenzeka ngenxa yamangqamuzana omdlavuza okhiqiza ngokweqile.
Ngemuva kokuthi igciwane lisuswe, amazinga we-thyroglobulin alinganiswa ngezikhathi ukuqinisekisa ukuthi liwela futhi kufanele ekugcineni lingabonakali.
Uma izivivinyo zakho zokulandelela ziqala ukuthola i-thyroglobulin futhi futhi ukuhlushwa kukhula, kungase kusho ukuthi umdlavuza ubuyile. Uma kukhona ezinye izicubu ze-thyroid ezisebenzayo noma isisu esiqhubeka nokukhiqiza i-thyroglobulin, udokotela angenza izivivinyo ezihlanganisa ukuskena kwe-iodine ye-radioactive, i-PET noma ezinye izikrini. Ukwelashwa okuqhubekayo njengokuhlinza, iodine e-radioactive noma i-radiation kungenziwa ukubulala amaseli asele.
Ukuhlolwa kwe-thyroglobulin ukuhlolwa kwegazi okwenziwe ngesampula segazi esivela emthonjeni. Kuthunyelwa ku-laboratory ukuhlolwa nokubika.
Ukuhlolwa kwe-Antibody
Ngezinye izikhathi umzimba wenza ama-antibodies ku-thyroglobulin, eyaziwa njenge-Tg antibodies. Lezi zinhlobo ze-autoantibodies zihlasela i-thyroglobulin futhi zibhubhise igciwane lakho le-thyroid. Ukuhlolwa kwe-thyroglobulin antibody kukusiza ukuxilonga izinkinga ze-thyroiditis kuhlanganise ne- Hashimoto's thyroiditis , isifo se-Graves nesifo se-autoimmune-kokubili izimo ze-hypothyroid nezimo ze-hyperthyroid. Uma kusolakala ukuthi unesifo se-thyroid, udokotela wakho uzokuthatha lolu hlelo. Kuyinto yokuhlolwa kwegazi eyenziwe egazini elidonsa kusuka emithanjeni yakho futhi ithunyelwe ebhokisatri.
Uma kungekho-antibodies e-thyroglobulin egazini lakho, imiphumela yokuhlolwa iyoba yinto engalungile. Isivivinyo esihle sisho ukuthi ama-antibodies e-thyroglobulin akhona egazini lakho. Lokhu kubonisa ukuthi ungase ube nenkinga nge-gland yakho yegciwane. Kungase futhi kusho ukuthi ukuhlolwa akulungile nokuthi kungadingeka ukuthi kuphindwe. Uma unemithi ye-hormone ye-thyroid , ingathinta imiphumela yokuhlolwa.
Imithombo:
I-Thyroglobulin, i-LabTestsOnline.org, i-American Association for Clinical Chemistry, ngoFebhuwari 24, 2015.
I-Antibodies ye-Thyroid, i-LabTestsOnline.org, i-American Association ye-Chemistry Clinical, ngo-February 26, 2016.