Ukuxhuma phakathi kwegciwane lakho kanye nemigraines yakho
I-irritable bowel syndrome (IBS) kanye ne- migraines kunezifo ezimbili ezihlobene nobuhlungu obuhlukile, kodwa nokho zihlanganyela ezinye izici. Lokhu kusikisela ukuthi kungenzeka amagatsha avamile anjengokuqala okuvela emthini ovela emthonjeni ovamile.
Eqinisweni, kuvamile ukuthi abantu abane-IBS nabo babe nemigraines futhi ngokufanayo. Ngokuvamile abantu babona okuningi ngesifo esisodwa, ngokuvamile esibuhlungu kakhulu noma esibucayi.
I-IBS ne-Migraines njenge-Syndromous Central Senensity
Ochwepheshe abaningi basikisela ukuthi kokubili imithi ye-migraines ne-irritable isifo sofuba yi-syndromes yokuzwela okuphakathi.
"Ephakathi" kubhekisela ebuhlungu obuvela ekuguqulweni kwesistimu yezinzwa zomphakathi, okuhlanganisa ubuchopho nomgogodla.
"Ukuzwela" kubhekisela ekubeni abantu abane-migraines ne-IBS banokuzwela okukhulu kokubili okudingekayo futhi akumele kubangele ukulimala, okusho ukuthi bazizwa bezinga eliphezulu lobuhlungu kunokuba evamile ngokubamba inaliti ( hyperlagesia ) noma ngisho nokungahambi kahle ( allodynia ).
Ukuzwela okuphakathi kwe-Migraines
Ngesikhathi sokuhlasela kwe-migraine, ososayensi bakholelwa ukuthi izitsha zegazi ezizungeze ubuchopho ziyaphuma. Lokhu kuguqulwa komthambo noma ukukhulisa kuvuselela i-trigeminal nerve (i- nerve cranial ) ukukhulula i-peptides njenge -peptide ehlobene ne-calcitonin ye-gene (i-CGRP) , ekhuthaza ukuvuvukala futhi idlulisele izibonakaliso zobuhlungu ebuchosheni-lokhu kubizwa ngokuthi yi-trigeminovascular pain path pathway.
Ekugcineni, ubuchopho buyaqondiswa izimbangela, okusho ukuthi amangqamuzana omgogodla ebuchosheni angathumela kalula imiyalezo ngokusebenzisa indlela yokubuhlungu ye-trigeminovascular ngoba eyenzile ngaphambili. Lokhu kuthiwa ukuzwela phakathi komphakathi futhi kungabangela ukuhlaselwa kwe-migraine ukuphakama kalula ngokuvezwa kwento efanayo.
Ukuzwela okuphakathi kwe-IBS
Okuphawulekayo kwe-IBS yi-visceral hypersensitivity, okusho ukuthi izitho zangaphakathi zomuntu (isb., Amathumbu, isisu, isisu) kubangele ukwanda kokuzwa ubuhlungu. Yingakho ukuvuvukala kwesisu noma ukuhlukanisa komuntu kungabangela kakhulu futhi kunciphise umuntu onokubambisana ne-IBS.
Ochwepheshe bakholelwa ukuthi i-visceral hypersensitivity ye-IBS ekugcineni iholela ekuzweleni ngaphakathi kwesistimu yenzwa yomphakathi. Lokhu kuzochaza ukuthi kungani abantu abaningi abane-IBS behlushwa izimpawu ezihlobene nobuhlungu (isib. Imilenze ye-migraines, ihlangene, neyomzimba) kanti abanye abenzi.
Amanye ama-syndromes wokuzwela okuphakathi
Okunye ukuphazamiseka okuvame ukuhlukaniswa njenge-central senitivity syndromes kufaka:
- i-fibromyalgia
- isifo esingapheliyo sokukhathala
- ubuhlungu obukhulu obungunaphakade
- i-cystitis yangaphakathi
Njengalezi ezinye izifo, i-IBS kanye ne-migraines itholakala yizibonakaliso zabo, okusho ukuthi akukho nebhu noma ukuhlolwa kwe-imaging ukuyiqinisekisa. Kunalokho kunezinqubo odokotela abazisebenzisayo ukunquma ukuthi isiguli sibhekene naso-uhlobo olufana nohlu lokuhlola, kodwa okunye okuningiliziwe.
I-Estrogen Link: i-IBS ne-Migraines
Ngaphandle kokuzwela okuphakathi okukhulu, kokubili i-IBS kanye ne-migraines zivame kakhulu kwabesifazane. Lokhu kusikisela ukuthi ama-hormone ocansi, ikakhulukazi i-estrogen, ithonya lezi zifo ezibuhlungu.
I-IBS ne-Estrogen
Ku-IBS, i-estrogen ayitholi kuphela ukuhlunga ubuhlungu nokuphendula kokucindezeleka ebuchosheni, kodwa futhi kuyathinta ubuzwe besisu sakho ebuhlungu, i-motility yezinto ezisemathunjini akho, ngisho nohlobo lwebhaktheriya elikhula emathunjini akho.
Lokhu kuthiwa, indima ye-estrogen ku-IBS iyinkimbinkimbi. Yingakho izifundo ziphikisana ngokuthi ngabe izigaba ezithile ezithinta i-hormone empilweni yowesifazane ziyasiza noma zibuhlungu kakhulu izimpawu zayo ze-IBS. Isibonelo, ucwaningo lubonisa ukuthi izigameko ze-IBS ziyancipha emva kokuya esikhathini , uma amazinga e-estrogen emzimbeni ephansi kakhulu. Lokho kuthiwa, abanye besifazane babika ukuthi bebuhlungu kakhulu izimpawu ze-GI, ikakhulukazi ukuqotshwa nokuqedwa, emva kokuya esikhathini.
I-Migraines ne-Estrogen
Emagraines, abesifazane ngokuvamile baphuthuka emigraini yabo ngesikhathi sesibili nesithathu sesisu sokukhulelwa lapho amazinga e-estrogen awo ephakeme. Ngokufanayo, ukuhamba esikhathini sokuya esikhathini kuvamile kuma-migraineurs abesifazane futhi bakholelwa ukuthi kubangelwa ukudonsa kwe-estrogen, okwenzeka ngaphambi nje kokugaya.
Ngomfanekiso ofanayo, abesifazane abaningi bahlangabezana nemigraines xaxa lapho beya esikhathini sokuya esikhathini, lapho umsebenzi wabo wokuphuma ovini uqala ukwehla kanye namazinga e-estrogen emzimbeni aqala ukuwa. Lokhu kuthiwa, imishanguzo yabo ibonakala ithuthukisa emva kokuya esikhathini sokuya esikhathini-isithombe esithile sokudideka, esikisela ukuthi kunezinto eziningi ezithandwayo.
Ezinye Izici Ezivamile ze-IBS ne-Migraines
Kuvamile ukukhathazeka kwengqondo okufana nokucindezeleka, ukukhathazeka, kanye / noma ukucindezeleka kokucindezeleka okulandela ngemuva kokubambisana ne-IBS kanye ne-migraines. Ukuba nesifo sengqondo ngaphezu kwesifo esibuhlungu kungumjikelezo onzima wokubangela omunye. Kuvame ukulukhuni ukuthola ukuthi yikuphi okufika kuqala, inkolelo ye "inkukhu ngokumelene neqanda". Kungakhathaliseki, ukuhlanganiswa kobuhlungu bomzimba kanye nokuphazanyiswa kwengqondo kungalimaza izinga lomuntu lokuphila nokusebenza kwansuku zonke.
Ngaphezu kwalokho, isayensi manje ivela ukuthi abantu abane-IBS kanye ne-migraines bangabelana ngezakhi zofuzo ezivamile, ikakhulukazi lezo ezihlobene ne-serotonin. Lokhu kusixhumanisi kuyathakazelisa ngoba kungasiza ososayensi ukudala ukwelashwa okuhlosiwe kokubili kwe-IBS kanye ne-migraines.
Ukwelapha i-IBS yakho ne-Migraines
Ukuze uphathe izimo zombili zombili, odokotela bavame ukuphakamisa inhlanganisela yezokwelapha ezibandakanya imithi kanye nemithi yokwelapha, njenge-biofeedback noma ukwelashwa kwengqondo-yokuziphatha. Ngaphezu kwalokho, izindlela zokwelapha ezihambisanayo, njenge- acupuncture , zivame ukusetshenziswa iziguli ukuze zithuthukise ukukhululeka kwabo ubuhlungu.
Ososayensi nabo babheka izindlela zokwelashwa ezilodwa ezingasiza zombili izimo, enye yokwelashwa kokudla. Esifundweni esisodwa esincane se-2013 esihlokweni sezinhloko, abahlanganyeli bobabili i-migraines ne-IBS banokudla kokuqeda, ngokusekelwe kumazinga aphezulu e-IgG egazini labo lapho evezwa kokudla okuthile. I-IgG i-antibody ne-marker yokuvuvukala emzimbeni. Ukudla kunciphisa kokubili izimpawu ze-IBS kanye nemigraines kulabo ababambiqhaza.
Ngaphansi
Ukuxhuma phakathi kwezinkinga ezimbili akusho ukuthi omunye ubangela enye, noma ukuthi ngeyodwa kusho ukuthi uzogcina omunye. Kusho nje ukuthi kukhona isixhumanisi.
Ukufunda izixhumanisi phakathi kwe-IBS kanye ne-migraines kusiza ososayensi ukuba baqonde kangcono ukuthi kungani lezi zinkinga ezibuhlungu zikhula futhi ukuthi odokotela bangabephatha kanjani kangcono-inqubo encane efuna ukuhumusha nokucwaninga okucophelelayo nokucishe.
Imithombo:
I-Aydinlar El et al. I-IgG-Based Elimination Emination Diet ku-Migraine Plus Irritable Bowel Syndrome. Izinwele . 2013; 53 (3): 514-25.
Chang FY, Lu CL. I-Irritable Bowel Syndrome ne-Migraine: Abaphikisi noma Abalingani? J Neurogastroenterol Motil. 2013; 19 (3): 301-11.
I-Moshiree B, i-Zhou Q, i-Price DD, I-Verne GN. Ukuzwela okuphakathi kwe-Visceral Pain Disorders. Gut . 2006; 55 (7): 905-8.
UMulak A, Taché Y, Larauche M. Sex Hormones ekuguquleni kwe-Irritable Bowel Syndrome. I-World J Gastroenterol . 2014; 20 (10): 2433-48.
Uluduz D et al. Isixhumanisi Phakathi Kwe-Migraine, Intukuthelo Uhlobo Lwezinyosi Ne-Irritable Bowel Syndrome: Izinkomba Zomtholampilo Nezofuzo. I-Neurology . 2016; 86 (16) IsongezoP4.120.