Odokotela Ngezinye Izikhathi Bhala Anticonvulsants for Management Pain
Uma ngabe uhlushwa yizinhlobo ezithile zobuhlungu obungapheli , ungase umangale uma uthola ukuthi imithi yokulwa nokuthumba ingasiza ekunciphiseni ubuhlungu bakho.
Ama-anticonvulsants, noma imithi yokulwa ne-anti-seizure, isebenza njengama- analgesics adjuvant . Lokhu kusho ukuthi bangakwazi ukuphatha ezinye izinhlobo zobuhlungu obungapheliyo nakuba zingaklanyelwe leyo njongo.
Ngesikhathi ukusetshenziswa okuyisisekelo kwemithi yokulwa nokuthunjwa kuvimbela ukugwinya, ama-anticonvulsants abonakala ephumelela ekuphatheni izinhlobo ezithile zobuhlungu obungapheliyo.
Lezi zihlanganisa ubuhlungu be-neuropathic , njenge-peripheral neuropathy, nezinsizwa ezinesihlungu ezingapheli , njenge-migraines.
Ingabe Imithi Elwa Nama-Anti-Seizure Isiza Ubuhlungu Besikhathi Esivamile?
Izifundo zenziwa ngokuphumelelayo kwemithi yokulwa nokuthunjwa yokuhlunguphazeka okungapheli.
Ucwaningo oluthile luphakamisa ukuthi ezinye izinhlobo zokwelashwa kwezidakamizwa zobuhlungu kufanele ziphenywe ngaphambi kokuba imithi yokulwa ne-anti-seizure imiselwe ukwelapha okungapheli , kanti abanye bathi i-anticonvulsants iyindlela yokwelashwa okuyisisekelo futhi inomthelela wokuba nemiphumela emibi yesikhathi eside.
Imithi embalwa yokulwa nokuthunjwa yi-FDA evunyelwe ukwelashwa okungapheliyo, okufaka i-carbamazepine (ye- trigeminal neuralgia ) ne-gabapentin (ye- neuralgia yangemva kwesikhathi , noma ubuhlungu be-shingles).
Ukusebenzisa imishanguzo yokulwa nokuthunjelwa kwezinye izinhlobo zobuhlungu obungapheli kubhekwa "ukusetshenziswa kwelebuli," njengoba kube nezifundo ezimbalwa zokuphenya ukusebenza kwazo ekuphatheni ubuhlungu obungapheli isikhathi eside.
Imithi Ejwayelekile Yokusetshenziswa Yokulwa Nezifo Zokuhlukunyezwa Okungapheli
Nakhu eminye imishanguzo yokulwa nokuthunjwa evame ukusetshenziselwa ukuphathwa ubuhlungu:
I-Gabapentin (Neurontin) . I-Gabapentin ivunyelwe ukwelashwa kwe-neuralgia yama-postherpic ehlala njalo. Kubuye futhi kuphumelele ekwelapheni ukwelashwa kwesifo sikashukela.
I-Carbamazepine (i-Tegretol) .
I-Carbamazepine yayivame ukwelashwa okunamandla okulwa nokuqothulwa kobuhlungu be-neuropathic, ikakhulukazi ekwelapheni i-neuralgia ye-trigeminal (okuyinto i-FDA evunyelwe yona). Ibuye iphumelele ekuhluphekeni kwesifo sikashukela kanye ne-neuralgia ye-postherpic.
I-Pregabalin (i-Lyrica) . I-Pregabalin iyimithi emisha yokulwa nokuthunjwa esetshenziselwa ubuhlungu obungapheli, ubuhlungu obuhambisana ne-postherpic neuralgia kanye ne-neuropathy yesifo sikashukela.
I-Tiagabine (Gabitril) . I-Tiagabine iyi-anti-seizure imithi esetshenziselwa ubuhlungu be-neuropathic ehambisana nokulimala kwenzwa, njengokuhlukunyezwa kwesilwane se-phantom .
I-Topiramate (i-Topomax) . I-Topiramate iyi-anti-seizure imithi evame ukusetshenziswa njengendlela yokwelapha i-prophylactic migraine. I-Prophylactics ithathwa ukuvimbela ubuhlungu kunokuba ilawule uma iqala.
I-Valproic Acid (i-Depakote) . I-Valproic acid iyi-anti-seizure imithi esetshenziselwa ubuhlungu be-migraine futhi ingase iphumelele ekwelapheni ezinye izinhlobo zobuhlungu benzwa.
I-Lamotrigene (i-Lamictal) . I-Lamotrigene ingasetshenziselwa ukwelapha ubuhlungu obuhlobene neuralgia ye-trigeminal kanye nama-syndromes obuhlungu obuphakathi, noma ubuhlungu obuhlobene nesifo sohlangothi.
Eminye Imithi Yokulwa Nezifo kanye Nokuhlupheka Okungapheli
Ngenxa yendlela abayisebenzisayo ngayo isimiso sezinzwa, imishanguzo elandelayo yokulwa nokuthunjwa ingase ibe usizo ekwelapheni ubuhlungu obungapheli.
Ukuphumelela kwabo ekulawuleni ubuhlungu obungapheli, noma kunjalo, akukafundwanga kahle:
- Phenytoin
- I-Phenobarbitol
- I-Clonazepam
- Oxcarbazepine
- I-Zonisamide
- Levetiracetam
Imiphumela emibi engenzeka
Imishanguzo yokulwa ne-anti-seizure ine-side effects uma iqhathaniswa nezinye izidakamizwa zesikhathi eside zokusebenzisa imithi, nakuba kubalulekile ukubalula.
Imiphumela emibi kakhulu ihlanganisa:
- ukulala
- isiyezi
- ukukhathala
Imishanguzo yokulwa ne-Anti-seizure ingase ibangele nemiphumela emibi elandelayo:
- ukuqotshwa
- isiyaluyalu
- ukudideka noma inkathazo yokugxila
- ukulahlekelwa ibhalansi noma inkathazo ngokusebenzisana
- umbono kabili
- inkulumo ehlehlisiwe
- ukuhlukumeza
- ukulahlekelwa ukudla
- umlomo owomile
Khumbula: Imithi iyathinta wonke umuntu ngokuhlukile. Okuhlangenwe nakho kwakho kuzoba okuhlukile. Uma unenkinga ngokuthatha imishanguzo yokuhlukunyezwa yokuhlunguphazeka okungapheli, khuluma nomhlinzeki wakho wezokunakekela impilo ngokushesha ngangokunokwenzeka.
Imithombo:
I-American Chronic Pain Association. Imishanguzo ye-APCA kanye nobuhlungu obungapheli: Isongezo 2007 .
I-Tremont-Lukats, i-IW, i-Megeff, i-C., no-Backonja, i-MM Anticonvulsants ye-Neuropathic Pain Syndromes: Izindlela Zokusebenza Nezindawo Ezikwelapha. Izidakamizwa. 2000 Nov; 60 (5): 1029-52.
Wiffen, PJ, Collins, S., McQuay, HJ, et al. Izidakamizwa ze-Anticonvulsant for Pain Acute and Chronic. Database Cochrane Yokuhlolwa Okuhlelekile 2005, Issue 2.